Hepatitis B virus genotypes and precore mutations in Scottish blood donors

Vox Sanguinis

Volumn 88, Issue 2, 2005, Pages 87-92

  Davidson, Fiona ^a,c   Lycett, C ^a   Sablon, E ^b   Petrik, J ^a   Dow, B C ^c  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b INNOGENETICS   (Belgium)

^c SCOTTISH NATIONAL BLOOD TRANSFUSION SERVICE   (United Kingdom)

Author keywords

Core promoter mutations; HBV genotypes; Line probe assay; Precore mutations

Indexed keywords

CORE PROTEIN; HEPATITIS B SURFACE ANTIBODY; HEPATITIS B SURFACE ANTIGEN; NUCLEOTIDE;

ADULT; AGED; ARTICLE; ASSAY; BLOOD DONOR; CONTROLLED STUDY; DEMOGRAPHY; DIAGNOSTIC KIT; FEMALE; GENETIC VARIABILITY; GENOTYPE; HEPATITIS B VIRUS; HUMAN; LINE PROBE ASSAY; MAJOR CLINICAL STUDY; MALE; MUTATION RATE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE ANALYSIS; SEROLOGY; UNITED KINGDOM; VIRUS MUTATION;

BLOOD DONORS; DNA MUTATIONAL ANALYSIS; GENE FREQUENCY; GENOTYPE; HEPATITIS B; HEPATITIS B ANTIGENS; HEPATITIS B E ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HUMANS; MUTATION; PREVALENCE; PROMOTER REGIONS (GENETICS); SCOTLAND; SEROLOGIC TESTS; VARIATION (GENETICS);

EID: 14944350622     PISSN: 00429007     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1423-0410.2005.00597.x     Document Type: Article

References (21)

1. Fattovich G: Natural history of hepatitis B. J Hepatol 2003; 39:S50-S58
2. Bruix J, Llovet JM: Hepatitis B virus and hepatocellular carcinoma. J Hepatol 2003; 39:S59-S63
3. Miyakawa Y, Mizokami M: Classifying hepatitis B virus genotypes. Intervirology 2003; 46:329-338
4. Stuyver L, De Gendt S, Van Geyt C, Zoulim F, Fried M, Schinazi RF, Rossau R: A new genotype of hepatitis B virus: complete genome and phylogenetic relatedness. J Gen Virol 2000; 81:67-74
5. Rodriguez-Frias F, Buti M, Jardi R, Cotrina M, Viladomiu L, Esteban R, Guardia J: Hepatitis B virus infection: precore mutants and its relation to viral genotypes and core mutations. Hepatology 1995; 22:1641-1647
6. Raimondo G, Pollicino T, Squadrito G: Clinical virology of hepatitis B virus infection. J Hepatol 2003; 39:S26-S30
7. Tong SP, Li JS, Vitvitski L, Kay A, Treepo C: Evidence for a base-paired region of hepatitis B virus pregenome encapsidation signal which influences the patterns of precore mutations abolishing HBe protein expression. J Virol 1993; 67:5651-5655
8. Lopez JL, Mbayed VA, Telenta PF, Gonzalez JE, Campos RH: 'Hbe minus' mutants of hepatitis B virus. Molecular characterization and its relation to viral genotypes. Virus Res 2002; 87:41-49
9. Sung JJ, Chan HL, Wong ML, Tse CH, Yuen SC, Tam JS, Leung NW: Relationship of clinical and virological factors with hepatitis activity in hepatitis B e antigen-negative chronic hepatitis B virus-infected patients. J Viral Hepat 2002; 9:229-234
10. Alestig E, Hannoun C, Horal P, Lindh M: Phylogenetic origin of hepatitis B virus strains with precore C-1858 variant. J Clin Microbiol 2001; 39:3200-3203
11. Ballard AL, Boxall EH: Epidemiology of precore mutants of hepatitis B in the United Kingdom. J Med Virol 2000; 62:463-470
12. Grandjacques C, Pradat P, Stuyver L, Chevallier M, Chevallier P, Pichoud C, Maisonnas M, Trepo C, Zoulim F: Rapid detection of genotypes and mutations in the pre-core promoter and the pre-core region of hepatitis B virus genome: correlation with viral persistence and disease severity. J Hepatol 2000; 33:430-439
13. Zarski JP, Marcellin P, Cohard M, Lutz JM, Bouche C, Rais A: Comparison of anti-HBe-positive and HBe-antigen-positive chronic hepatitis B in France. French Multicentre Group. J Hepatol 1994; 20:636-640
14. Fukuda R, Mohammad R, Hamamoto S, Ishimura N, Ishihara S, Akagi S, Watanabe M, Kinosha Y: Clinical relevance of precore and basal core promoter variants of hepatitis B virus during natural hepatitis B e antigen seroconversion may be overstated. J Pediatr Gastroenterol Nutr 2001; 33:301-306
15. Bozdayi AM, Bozkaya H, Turkyilmaz AR, Saryodlu M, Cetinkaya H, Karayalcin S, Yurdaydin C, Uzunalimoglu O: Nucleotide divergences in the core promoter and precore region of genotype D hepatitis B virus in patients with persistently elevated or normal ALT levels. J Clin Virol 2001; 21:91-101
16. Chen WN, Oon CJ: Mutations and deletions in core promoter and precore stop codon in relation to viral replication and liver damage in Singaporean hepatitis B virus carriers. Eur J Clin Invest 2000; 30:787-792
17. Schlager F, Schaefer S, Metzler M, Gratzki N, Lampert F, Gerlich WH, Repp R: Quantitative DNA fragment analysis for detecting low amounts of hepatitis B virus deletion mutants in highly viremic carriers. Hepatology 2000; 32:1096-1105
18. Fattovich G: Natural history and prognosis of hepatitis B. Semin Liver Dis 2003; 23:47-58
19. Bonino F, Brunetto MR: Chronic hepatitis B e antigen (HBeAg) negative, anti-HBe positive hepatitis B. an overview. J Hepatol 2003; 39:S160-S163
20. Kane M: Global programme for control of hepatitis B infection. Vaccine 1995; 13:S47-S49
21. Imamura T, Yokosuka O, Kurihara T, Kanda T, Fukai K, Imazeki F, Saisho H: Distribution of hepatitis B viral genotypes and mutations in the core promoter and precore regions in acute forms of liver disease in patients from Chiba. Japan Gut 2003; 52:1630-1637