Effects of Guiyuanfang and autologous transplantation of bone marrow stem cells on rats with liver fibrosis

World Journal of Gastroenterology

Volumn 11, Issue 8, 2005, Pages 1155-1160

  Wu, Li Mao ^a   Li, Lian Da ^b   Liu, Hong ^c   Ning, Ke Yong ^b   Li, Yi Kui ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b XIYUAN HOSPITAL   (China)

^c GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Bone marrow stem cells; Guiyuanfang; Liver fibrosis; Transplantation

Indexed keywords

ALCOHOL; AMINOTRANSFERASE; CARBON TETRACHLORIDE; CHINESE DRUG; COLLAGEN; GUIYUANFANG; HYALURONIC ACID; HYDROXYPROLINE; LIPID; PROCOLLAGEN TYPE 3 AMINOPROPEPTIDE; UNCLASSIFIED DRUG; UROKINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; BIOCHEMISTRY; CELL PROLIFERATION; CHINESE MEDICINE; CONTROLLED STUDY; DISEASE MODEL; GRAFT SURVIVAL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIVER FIBROSIS; LIVER FUNCTION; LIVER PARENCHYMA; MEDICAL ASSESSMENT; NONHUMAN; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; RAT; SCORING SYSTEM; TREATMENT OUTCOME;

EID: 14844361718     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i8.1155     Document Type: Article

References (21)

1. Schuppan D, Jia JD, Brinkhaus B, Hahn EG. Herbal products for liver diseases: A therapeutic challenge for the new millennium. Hepatology 1999; 30: 1099-1104
2. Slehria S, Rajvanshi P, Ito Y, Sokhi RP, Bhargava KK, Palestro CJ, McCuskey RS, Gupta S. Hepatic Sinusoidal vasodilators improve transplanted cell engraftment and ameliorate microcirculatory perturbations in the liver. Hepatology 2002; 35: 1320-1328
3. Kobayashi N, Ito M, Nakamura J, Cai J, Gao C, Hammel JM, Fox IJ. Hepatocyte transplantation in rats with decompensated cirrhosis. Hepatology 2000; 31: 851-857
4. Gagandeep S, Rajvanshi P, Sokhi RP, Slehria S, Palestro CJ, Bhargava KK, Gupta S. Transplanted hepatocytes engraft, survive, and proliferate in the liver of rats with carbon tetrachloride-induced cirrhosis. J Pathol 2000; 191: 78-85
5. Chinzei R, Tanaka Y, Shimizu-Saito K, Hara Y, Kakinuma S, Watanabe M, Teramoto K, Arii S, Takase K, Sato C, Terada N, Teraoka H. Embryoid-body cells derived from a mouse embryonic stem cell line show differentiation into functional hepatocytes. Hepatology 2002; 36 22-29
6. Guha C, Parashar B, Deb NJ, Garg M, Gorla GR, Singh A, Roy-Chowdhury N, Vikram B, Roy-Chowdhury J. Normal hepatocytes correct serum bilirubin after repopulation of gunn rat liver subjected to irradiation/partial resection. Hepatology 2002; 36: 354-362
7. Fox IJ, Chowdhury JR, Kaufman SS, Goertzen TC, Chowdhury NR, Warkentin PI, Dorko K, Sauter BV, Strom SC. Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation. N Engl J Med 1998; 388: 1422-1426
8. Strom SC, Fisher RA, Thompson MT, Sanyal AJ, Cole PE, Ham JM, Posner MP. Hepatocyte transplantation as a bridge to orthotopic liver transplantation in terminal liver failure. Transplantation 1997; 63: 559-569
9. Ott M, Schmidt HH, Cichon G, Manns MP. Emerging therapies in hepatology: Liver-directed gene transfer and hepatocyte transplantation. Cells Tissues Organs 2000; 167: 81-87
10. Dorshkind K. Multilineage development from adult bone marrow cells. Nat Immunol 2002; 3: 311-313
11. Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, Reyes M, Lenvik T, Lund T, Blackstad M, Du J, Aldrich S, Lisberg A, Low WC, Largaespada DA, Verfaillie CM. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418: 41-49
12. Krause DS, Theise ND, Collector MI, Henegariu O, Hwang S, Gardner R, Neutzel S, Sharkis SJ. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 2001; 105: 369-377
13. Brunt EM. Grading and staging the Histopathological lesions of chronic hepatitis: The knodell histology activity index and beyond. Hepatology 2000; 31: 241-246
14. Fox IJ. Transplantation into and inside the liver. Hepatology 2002; 36: 249-251
15. Alison MR, Poulsom R, Jeffery R, Dhillon AP, Quaglia A, Jacob J, Novelli M, Prentice G, Williamson J, Wright NA. Hepatocytes from nonhepatic adult stem cells. Nature 2000; 406: 257
16. Theise ND, Nimmakayalu M, Gardner R, Illei PB, Morgan G, Teperman L, Henegariu O, Krause DS. Liver from bone marrow in humans. Hepatology 2000; 32: 11-16
17. Lagasse E, Connors H, Al-Dhalimy M, Reitsma M, Dohse M, Osborne L, Wang X, Finegold M, Weissman IL, Grompe M. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000; 6: 1229-1234
18. Schwartz RE, Reyes M, Koodie L, Jiang Y, Blackstad M, Lund T, Lenvik T, Johnson S, Hu WS, Verfaillie CM. Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells. J Clin Invest 2002; 109: 1291-1302
19. Laconi S, Pillai S, Porcu PP, Shafritz DA, Pani P, Laconi E. Massive liver replacement by transplanted hepatocytes in the absence of exogenous growth stimuli in rats treated with retrorsine. Am J Pathol 2001; 158: 771-777
20. Miyazaki M, Akiyama I, Sakaguchi M, Nakashima E, Okada M, Kataoka K, Huh N. Improved conditions to induce hepatocytes from rat bone marrow cells in culture. Biochem Biophys Res Commun 2002; 298: 24-30
21. Mallet VO, Mitchell C, Mezey E, Fabre M, Guidotti JE, Renia L, Coulombel L, Kahn A, Gilgenkrantz H. Bone marrow transplantation in mice leads to a minor population of hepatocytes that can be selectively amplified in vivo. Hepatology 2002; 35: 799-804