Factor V Leiden in patients with venous thrombosis in Slovak population

General Physiology and Biophysics

Volumn 23, Issue 4, 2004, Pages 435-442

  Simkova, M ^a   Batorova, A ^b   Dostalova, K ^a   Pozgayova, S ^a   Simko, F ^a   Kovacs, Laszlo ^a  

^a Faculty of Medicine of Comenius University and University Hospital Bratislava   (Slovakia)

^b UNIVERSITY HOSPITAL BRATISLAVA   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 5 LEIDEN;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; DISEASE CARRIER; FAMILY HISTORY; FEMALE; FREQUENCY ANALYSIS; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; LEG THROMBOSIS; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PATHOLOGICAL ANATOMY; PREVALENCE; RARE DISEASE; RECURRENT DISEASE; SLOVAKIA; THROMBOPHILIA; VEIN THROMBOSIS; VENOUS THROMBOEMBOLISM;

FACTOR V; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HUMANS; MALE; PREVALENCE; SLOVAKIA; VENOUS THROMBOSIS;

EID: 14844347848     PISSN: 02315882     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Arnaldi L. A., Pretti F. A., Zampieri J. P., Ramos C. F., Arruda V. R., Annichino-Bizacchi J. M. (2001): Antithrombin deficiency in Brazilian patients with venous thrombosis: molecular characterisation of a single splice site mutation, an insertion and a de novo point mutation. Thromb. Res. 104, 397-403
2. Arruda V. R., Annichino-Bizacchi J. M., Costa F. F., Reitsma P. H. (1995): Factor V Leiden (FVQ 506) is common in a Brazilian population. Am. J. Hematol. 49, 242-243
3. Bertina R. M., Koeleman B. P., Koster T., Rosendaal F. R., Dirven R. J., de Roude H., van der Velden P. A., Reitsma P. H. (1994): Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 369, 64-67
4. Bucciarelli P., Rosendaal F. R., Tripodi A., Mannucci P. M., De Stefano V., Palareti G., Finazzi G., Baudo F., Quintavalla R. (1999): Risk of venous thromboembolism and clinical manifestations in carriers of antithrombin, protein C, protein S deficiency, or activated protein C resistance; a multicenter collaborative family study. Arterioscler. Thromb. Vasc. Biol. 19, 1026-1033
5. De Stefano V., Finazzi G., Mannucci P. M. (1996): Inherited thrombophilia: pathogenesis, clinical syndromes, and management. Blood 87, 3531-3544
6. Dulicek P., Maly J., Safarova M. (2000): Risk of thrombosis in patients homozygous and heterozygous for factor V Leiden in the East Bohemian region. Clin. Appl. Thromb. Hemost. 6, 87-89
7. Dulicek P., Maly J., Pesuavova L., Pecka M. (2002): Prevalence of inherited thrombophilia in young thrombosis patients from the East Bohemian region. Blood Coagul. Fibrinolysis 13, 569-573
8. Eckman M. H., Singh S. K., Erban J. K., Kao G. (2002): Testing for factor V Leiden in patients with pulmonary or venous thromboembolism: a cost-effectiveness analysis. Med. Decis. Making 22 108-124 (in German)
9. Ehrenforth S., Klinke S., von Depka Prondzinski M., Kreuz W., Ganser A., Scharrer I. (1999): Activated protein C resistance and venous thrombophilia: molecular genetic prevalence study in the German population. Dtsch. Med. Wochenschr. 124, 783-787 (in German)
10. Federman D. G., Moriarty J. P., Kravetz J. D., Kirsner R. S. (2002): Thrombosis: a new culprits in an old disorder. Panminerva Med. 44, 107-113
11. Gardner J. (2003): Factor V Leiden with deep venous thrombosis. Clin. Lab. Sci. 16, 6-9
12. Herrmann F. H., Koesling M., Schroder W., Altman R., Jimenez Bonill R., Lopaciuk S., Perez-Requejo J. L., Singh J. R. (1997): Prevalence of factor V Leiden mutation in various population. Genet. Epidemiol. 14, 403-411
13. Kalafatis M., Simioni P., Tormene D., Beck D. O., Luni S., Girolami A. (2002): Isolation and characterisation of an antifactor V antibody causing activated protein C resistance from a patient with severe thrombotic manifestations. Blood 99, 3985-3992
14. Lane D. A., Mannucci P. M., Bauer K. A., Bertina R. M., Bochkov N. P., Boulyjenkov V., Chandy M., Dahlbck B., Ginter E. K., Miletich J. P., Rosendaal F. R., Seligsohn U. (1996): Inherited trombophilia: Part 1. Thromb. Haemost. 76, 651-662
15. Murray C. J., Lopez A. D. (1997): Mortality by cause for eight regions of the world: global burden of disease study. Lancet 349 1269-1276
16. Nizankowska-Mogilnicka, E., Adamek L., Grzanka P., Domagala T. B., Krzanowsky M., Szczeklik A. (2003): Genetic polymorphisms associated with acute pulmonary embolism and deep venous thrombosis. Eur. Respir. J. 21, 25-30
17. Pabinger I., Brucker S., Kyrle P. A., Schneider B., Korninger H. C., Niessner H., Lechner K. (1992): Hereditary deficiency of antithrombin III, protein C and protein S: prevalence in patients with a history of venous thrombosis and criteria for rational patient screening. Blood Coagul. Fibrinolysis 3, 547-553
18. Paseka J., Unzeitig V., Cibula D., Bulikova A., Matyskova M., Chroust K. (2000): The factor V Leiden mutation in users of hormonal contraceptives. Ceska Gynekol. 65, 156-159 (in Czech)
19. Poort S. R., Rosendaal F. R., Reitsma P. H., Bertina R. M. (1996): A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 88, 3698-3703
20. Press R. D., Bauer K. A., Kujovich J. L., Heit J. A. (2002): Clinical utility of factor V Leiden (R506Q) testing for the diagnosis and management of thromboembolic disorders. Arch. Pathol. Lab. Med. 126 1304-1318
21. Ridker P. M., Hennekens C. H., Lindpaintner K., Stampfer M. J., Eisenberg P. R., Miletich J. P. (1995): Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men. N. Engl. J. Med. 332 912-917
22. Rodeghiero F., Tosetto A. (1999): Activated protein C resistance and factor V Leiden mutation are independent risk factors for venous thromboembolism. Ann. Intern. Med. 130, 643-650
23. Rosendaal F. R., Koster T., Vandenbroucke J. P., Reitsma P. H. (1995): High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance). Blood 85, 1504-1508
24. Sheppard D. R. (2000): Activated protein C resistance: the most common risk factor for venous thromboembolism. J. Am. Board Fam. Pract. 13, 111-115
25. Simkova M., Simko F., Kovacs L. (2001): Resistance to activated protein C - frequent etiologic factor for venous thrombosis. Bratisl. Lek. Listy 102, 240-247
26. Stankovics J., Melegh B., Nagy A., Kis A., Molnar J., Losonczy H., Schuler A., Kosztolanyi G. (1998): Incidence of factor V G1681A (Leiden) mutation in sampling from the Hungarian population. Orv. Hetil. 139, 1161-1163
27. Svensson P. J., Dahlbäck B. (1994): Resistance to activated protein C as a basis for venous thrombosis. N. Engl. J. Med. 330, 517-522