Prevalence of inherited thrombophilia in young thrombosis patients from the East Bohemian region

Blood Coagulation and Fibrinolysis

Volumn 13, Issue 6, 2002, Pages 569-573

  Dulíček, Petr ^a   Maly J ^a   Pesavova L ^a   Pecka, M ^a  

^a UNIVERSITY HOSPITAL HRADEC KRALOVE   (Czech Republic)

Author keywords

Anticoagulation treatment; Factor V Leiden; Inherited thrombophilia; Venous thromboembolism

Indexed keywords

ANTITHROMBIN III; BLOOD CLOTTING FACTOR 5; LUPUS ANTICOAGULANT; PROTEIN C; PROTEIN S; PROTHROMBIN;

ADULT; ANTICOAGULATION; ANTITHROMBIN III DEFICIENCY; ARTICLE; BLOOD CLOTTING FACTOR 5 DEFICIENCY; CZECH REPUBLIC; FEMALE; HUMAN; HYPERCOAGULABILITY; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; PROTEIN C DEFICIENCY; PROTEIN DEFICIENCY; PROTEIN S DEFICIENCY; PROTHROMBIN DEFICIENCY; THROMBOEMBOLISM; THROMBOPHILIA; THROMBOSIS; VEIN THROMBOSIS; ADOLESCENT; ANTIPHOSPHOLIPID SYNDROME; BLOOD; FAMILY HEALTH; GENETIC PREDISPOSITION; GENETICS; ONSET AGE; RECURRENT DISEASE; RISK FACTOR;

ADOLESCENT; ADULT; AGE OF ONSET; ANTIPHOSPHOLIPID SYNDROME; ANTITHROMBIN III DEFICIENCY; CZECH REPUBLIC; FAMILY HEALTH; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; PREVALENCE; PROTEIN C DEFICIENCY; PROTEIN S DEFICIENCY; PROTHROMBIN; RECURRENCE; RISK FACTORS; THROMBOPHILIA; THROMBOSIS;

EID: 0036742102     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001721-200209000-00013     Document Type: Article

References (15)

1. Nordström M, Lindblad B, Berqvist D, Kjellström T. A prospective study of the incidence of deep-vein thrombosis within a defined urban population. J Intern Med 1992; 232: 155-160.
2. Egeberg O. Inherited antithrombin deficiency causing thrombophilia. Thromb Diath Haemorrh 1965; 13: 516-530.
3. Griffin JH, Evatt B, Zimmerman TS, Kleiss AJ, Wideman C. Deficiency of protein C in congenital thrombotic disease. J Clin Invest 1981; 68: 1370-1373.
4. Comp PC, Esmon CT. Recurrent venous thromboembolism in patients with a partial deficiency of protein S. N Engl J Med 1984; 311: 1525-1528.
5. Schwarz MP, Fisher A, Hopmeier P, Batard MA, Griffin JH. Plasma protein S deficiency in familial thrombotic disease. Blood 1984; 64: 1297-1300.
6. Dalhbäck B, Carlsson M, Svensson PJ. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C; prediction of a cofactor to activated protein C. Proc Natl Scad Sci USA 1993; 90: 1004-1008.
7. Bertina RM, Koeleman BPC, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, et al. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994; 369: 64-67.
8. Rees DC, Cox M, Clegg JB. World distribution of factor V Leiden. Lancet 1995; 346: 1133-1134.
9. Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an in venous thrombosis. Blood 1996; 88: 3698-3703.
10. Brandt JT, Triplett DA, Alving B, Scharrer I. Criteria for the diagnosis of lupus anticoagulant: an update. Thromb Haemost 1995; 74: 1185-1190.
11. Koster T, Rosendaal FR, de Ronde H, Briet E, Vandenbroucke JP, Bertina RM. Venous thrombosis due to a poor anticoagulant response to activated protein C. Leiden Thrombophilia Study. Lancet 1993; 342: 1503-1506.
12. Rosendaal FR, Koster T, Vandenbroucke JP, Reitsma PH. High risk of thrombosis in patients homozygous for FV Leiden (activated protein C resistance). Blood 1995; 85: 1504-1508.
13. Kearon C. Epidemiology of venous thromboembolism. Semin Vasc Med 2001; 1: 7-25.
14. De Moerloose P, Alhenc-Gelas M, Boehlen F, Bounameaux H, Aiach M. Deep vein thrombosis and thrombophilia: indications and clinical implications. Semin Vasc Med 2001; 1: 89-95.
15. Walker ID, Greaves M, Preston FE. Guideline: investigation and management of heritable thrombophilia. Br J Haematol 2001; 114: 512-528.