Development and characterization of rat monoclonal antibodies to denatured mouse angiotensin-converting enzyme

Tissue Antigens

Volumn 65, Issue 3, 2005, Pages 240-251

  Balyasnikova, I V ^a   Metzger, R ^b   Sun, Z L ^a   Berestetskaya, Y V ^a,c   Albrecht II, R F ^a   Danilov, Sergei M ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF MUNICH   (Germany)

^c POCARD Ltd   (Russian Federation)

Author keywords

Angiotensin converting enzyme; CD143; Immunohistochemistry; Monoclonal antibody; Mouse; Paraffin section; Western blotting

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 4G6; MONOCLONAL ANTIBODY 5C4; MONOCLONAL ANTIBODY B12; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ANTIBODY DETECTION; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; EMBEDDING; ENDOTHELIUM CELL; ENZYME DENATURATION; EPIDIDYMIS; EPITHELIUM CELL; EPITOPE MAPPING; INTESTINE; KIDNEY PROXIMAL TUBULE; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEOMICS; RAT; SENSITIVITY ANALYSIS; SPECIES IDENTIFICATION; SPERMATID; SPERMATOZOON; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; CATTLE; CROSS REACTIONS; EPITOPE MAPPING; HUMANS; HYBRIDOMAS; MICE; MOLECULAR SEQUENCE DATA; PEPTIDYL-DIPEPTIDASE A; PROTEIN DENATURATION; PROTEIN STRUCTURE, TERTIARY; RABBITS; RATS; TISSUE DISTRIBUTION;

ANIMALIA; BOVINAE; ORYCTOLAGUS CUNICULUS;

EID: 14844309723     PISSN: 00012815     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-0039.2005.00364.x     Document Type: Article

References (48)

1. Corvol P, Williams TA, Soubrier F. Dipeptidyl dipeptidase: angiotensin-converting enzyme. Methods Enzymol 1995: 248: 283-305.
2. Dzau VJ, Bernstein K, Celermajer D et al. The relevance of tissue angiotensin-converting enzyme: manifestations in mechanistic and endpoint data. Am J Cardiol 2001: 88: 1L-20L.
3. Fuchs S, Frenzel K, Xiao HD et al. Newly recognized physiologic and pathophysiologic actions of tissue angiotensin-converting enzyme. Curr Hypertens Rep 2004: 6: 124-8.
4. Soubrier F, Alhenc-Gelas F, Hubert C et al. Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning. Proc Natl Acad Sci USA 1988: 85: 9386-90.
5. Sibony M, Gasc JM, Soubrier F, Alhenc-Gelas F, Corvol P. Gene expression and tissue localization of the two isoforms of angiotensin I converting enzyme. Hypertension 1993: 21: 827-35.
6. Langford KG, Zhou Y, Russel LD, Wilcox JN, Bernstein KE. Regulated expression of testis angiotensin-converting enzyme during spermatogenesis in mice. Biol Reprod 1993: 48: 1210-8.
7. Pauls K, Fink L, Franke FE. Angiotensin-converting enzyme (CD 143) in neoplastic germ cells. Lab Invest 1999: 79: 1425-35.
8. Pauls K, Metzger R, Steger K, Klonisch T, Danilov S, Franke FE Isoforms of angiotensin I-converting enzyme in the development and differentiation of human testis and epididymis. Andrologia 2003: 35: 32-42.
9. Danilov SM, Franke FE, Erdos EG. Angiotensin-converting enzyme (CD143). In: Kishimoto T et al., eds. Leucocyte Typing VI: White Cell Differentiation Antigens. New York: Garland Publishing Inc., 1997: 746-9.
10. Franke FE, Metzger R, Bohle R-M, Kerkman L, Alhenc-Gelas F, Danilov SM. Angiotensin I-converting enzyme (CD 143) on endothelial cells in normal and in pathological conditions. In: Kishimoto T et al., eds. Leucocyte Typing VI: White Cell Differentiation Antigens. New York: Garland Publishing Inc. 1997: 749-51.
11. Silverstein E, Pertschuk LP, Friedland J. Immunofluorescent localization of angiotensin converting enzyme in epithelioid and giant-cells of sarcoidosis granulomas. Proc Natl Acad Sci USA 1979: 79: 6646-8.
12. Falkenhahn M, Franke F, Bohle RM et al. Cellular distribution of angiotensin converting enzyme after myocardial infarction. Hypertension 1995: 25: 219-26.
13. Diet F, Pratt RE, Berry GJ, Momose N, Gibbons GH, Dzau VJ. Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease. Circulation 1996: 94: 2756-67.
14. Haberbosch W, Bohle R, Franke F et al. The expression of angiotensin-I converting enzyme in human atherosclerotic plaques is not related to the deletion/insertion polymorphism but to the risk of restenosis after directional coronary atherectomy. Atherosclerosis 1997: 130: 203-13.
15. Ohishi M, Ueda M, Rakugi H et al. Enhanced expression of angiotensin-converting enzyme is associated with progression of coronary atherosclerosis in humans. J Hypertens 1997: 15: 1295-302.
16. Metzger R, Bohle RM, Chumachenko P, Danilov SM, Franke FE. CD 143 in the development of atherosclerosis. Atherosclerosis 2000: 150: 21-31.
17. Metzger R, Bohle R-M, Kerkman L et al. Distribution of angiotensin I-converting enzyme (CD 143) in the normal human kidney and in non-neoplastic kidney diseases. Kidney Int 1999: 56: 1442-54.
18. Schuster DP, Crouch EC, Parks WC, Johnson T, Botney MD. Angiotensin converting enzyme expression in primary pulmonary hypertension. Am J Respir Crit Care Med 1996: 154: 1087-91.
19. Orte C, Polak JM, Haworth SG, Yacoub MH, Morrell NW. Expression of pulmonary vascular angiotensin-converting enzyme in primary and secondary plexiform pulmonary hypertension. J Pathol 2000: 192: 379-84.
20. Morrel NW, Atochina EN, Morris KG, Danilov SM, Stenmark KG. Angiotensin-converting enzyme expression is increased in small pulmonary arteries of rats with hypoxia-induced pulmonary hypertension. J Clin Invest 1995: 96: 1823-33.
21. Okada K, Bernstein ML, Zhang W, SchusterDP, Botney MD. Angiotensin-converting enzyme inhibition delays pulmonary vascular neointimal formation. Am J Respir Crit Care Med 1998: 158: 939-50.
22. Krege JH, John SW, Langenbach LL et al. Male-female differences in fertility and blood pressure in ACE-deficient mice. Nature 1995: 375: 146-8.
23. Kessler SP, Rowe TM, Gomos JB, Kessler PM, Sen GC. Physiological non-equivalence of the two isoforms of angiotensin-converting enzyme. J Biol Chem 2000: 275: 26259-64.
24. Franke FE, Pauls K, Kerkman L et al. Somatic Isoform of angiotensin I-converting enzyme in the pathology of testicular germ cell tumors. Hum Pathol 2000: 31: 1466-76.
25. Danilov S, Jaspard E, Churakova T et al. Structure-function analysis of angiotensin I-converting enzyme using monoclonal antibodies. J Biol Chem 1994: 269: 26806-14.
26. Balyasnikova IV, Metzger R, Franke FE, Danilov SM. Monoclonal antibodies to denatured human ACE (CD143): broad species specificity, reactivity on paraffin-section, and detection of subtle conformational changes in the C-terminal domain of ACE. Tissue Antigem 2003: 61: 49-62.
27. O'Brien KD, Shavelle DM, Caulfield MT et al. Association of angiotensin-converting enzyme with low-density lipoprotein in aortic valvular lesions and in human plasma. Circulation 2002: 106: 2224-30.
28. Sakharov IY, Dukhanina EA, Puchnina EA, Danilov SM, Muzykantov VR. Oxidative inactivation of the angiotensin-converting enzyme. Biokhimiia 1991: 56: 55-62 (Russian).
29. Friedland J, Silverstein E. A sensitive fluorometric assay for serum angiotensin-converting enzyme. Am J Pathol 1976: 66: 416-24.
30. Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975: 256: 495-7.
31. Balyasnikova IV, Gavrilyuk VD, McDonald TB, Berkowitz RA, Miletich DJ, Danilov SM. Antibody-mediated lung endothelium targeting: in vitro model of lung endothelium targeting using a cell line expressing angiotensin-converting enzyme. Tumor Targeting 1999: 4: 70-83.
32. Marcic B, Deddish PA, Jackman HL, Erdos EG, Tan F. Effect of N-terminal sequence of ACE on the properties of its C-domain. Hypertension 2000: 36: 116-21.
33. Balejaswikala IV, Woodman ZL, Albrecht RFH, Natesh R, Acharya KR, Sturrock ED, Danilov SM. The localisation of an N-domain region of angiotensin-converting enzyme involved in the regulation of ectodomain shedding using monoclonal antibodies. J Proteome Res 2005: in press.
34. Deddish PA, Wang J, Michel B et al. Naturally occurring active N-domain of human angiotensin I-converting enzyme. Proc Natl Acad Sci USA 1994: 91: 7807-11.
35. Nishida S, Nohno T, Hirokawa Y, Matsuki M, Tanaka J, Ichihara K. The higher immunoreactivity to ACE (angiotensin-converting enzyme) in patients with type 2 diabetes mellitus than in non-diabetic individuals. Endocr J 2003: 50: 209-13.
36. Nishida S, Sasaki T, Kimura H et al. Immunization with ACE (angiotensin-converting enzyme) develops diabetic changes in the kidney and retina in diabetogenic rats. Endocr J 2003: 50: 801-7.
37. Lantz I, Nyberg F, Terrenius L. Molecular heterogeneity of angiotensin-converting enzyme in human cerebrospinal fluid. Biochem Int 1991: 23: 941-8.
38. Casarini DE, Plavinik FL, Zanella MT et al. Angiotensin-converting enzyme from human urine of mild hypertensive untreated patients resemble the N-terminal fragment of human angiotensin I-converting enzyme. Int J Biochem Cell Biol 2001: 33: 75-85.
39. Marques GD, Quinto BM, Plavinik FL, Krieger JE, Marson O, Casarini DE. N-domain angiotensin I-converting enzyme with 80 kDa as a possible genetic marker of hypertension. Hypertension 2003: 42: 693-701.
40. Deddish PA, Wang L-X, Jackman HL et al. Single-domain angiotensin-I converting enzyme (Kininase II): characterization and properties. J Pharmacol Exp Ther 1996: 279: 1582-9.
41. Sturrock ED, Danilov SM, Riordan JF. Limited proteolysis of human kidney angiotensin-converting enzyme and generation of catalytically active N- and C-terminal domains. Biochem Biophys Res Commun 1997: 236: 16-9.
42. Sugimura K, Tian X-L, Hoffman S, Ganten D, Bader M. Alternative splicing of the mRNA coding for the human endothelial angiotensin-converting enzyme: a new mechanism for solubilization. Biochem Biophys Res Commun 1998: 247: 466-72.
43. Yonea K, Kumamoto H, Chiba S et al. A novel isoform of human angiotensin-converting enzyme by alternative splicing. Circulation 1998: 98: I-724 (Abstract).
44. Balyasnikova IV, Sun Z-L, Franke FE et al. Monoclonal antibodies 1B3 and 5C8 as probes for monitoring the integrity of the C-terminal end of soluble angiotensin-converting enzyme. Hybridoma Hybridomics 2005: 24: 14-26.
45. Danilov SM, Gavriljuk VD, Franke FE et al. Lung uptake of antibodies to endothelial antigens: key determinants of vascular immunotargeting. Am J Physiol Lung Cell Mol Physiol 2001: 280: L1335-47.
46. Borrebaeck CA. Antibodies in diagnostics from immunoassays to protein chips. Immunol Today 2000: 21: 379-82.
47. Albala JS. Array-based proteomics: the latest chip challenge. Expert Rev Mol Diagn 2001: 1: 145-52.
48. Chubb AJ, Schwager SL, Woodman ZL, Ehlers MR, Sturrock ED. Defining the boundaries of the testis angiotensin-converting enzyme ectodomain. Biochem Biophys Res Commun 2002: 297: 1225-30.