Synthesis and evaluation of the permeability transition inhibitory characteristics of paramagnetic and diamagnetic amiodarone derivatives

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 7, 2005, Pages 2629-2636

  Kálai, Tamás ^a   Várbiró, Gábor ^a   Bognár, Zita ^a   Pálfi, Anita ^a   Hantó, Katalin ^a   Bognár, Balázs ^a   Osz, Erzsébet ^a   Sümegi, Balázs ^a   Hideg, Kálmán ^a  

^a UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Amiodarone; Langendorff perfused heart; Mitochondria; Nitroxides; Permeability transition

Indexed keywords

2 BUTYL 3 [3,5 DIIODO 4 [2 N ETHYL N (1 OXYL 2,2,5,5 TETRAMETHYL 2,5 DIHYDRO 1H PYRROL 3 YLMETHYL)ETHYL]OXYBENZOYL]BENZOFURAN; 2 BUTYL 3 [3,5 DIIODO 4 [2 [N ETHYL N (2,2,5,5 TETRAMETHYL 2,5 DIHYDRO 1H PYRROL 3 YLMETHYL)ETHYL]]OXYBENZOYL]BENZOFURAN; 2 METHYL 3 [3,5 DIIODO 4 (1 HYDROXY 2,2,6,6 TETRAMETHYL 1,2,5,6 TETRAHYDROPYRIDIN 4 YLMETHYL)OXYBENZOYL]BENZOFURAN; 2 METHYL 3 [3,5 DIIODO 4 (1 OXYL 2,2,5,5 TETRAMETHYL 2,5 DIHYDRO 1H PYRROL 3 YLMETHYL)OXYBENZOYL]BENZOFURAN; 2 METHYL 3 [3,5 DIIODO 4 (1 OXYL 2,2,6,6 TETRAMETHYL 1,2,5,6 TETRAHYDROPYRIDIN 4 YLMETHYL)OXYBENZOYL]BENZOFURAN; 2 METHYL 3 [3,5 DIIODO 4 (1,2,2,5,5 PENTAMETHYL 2,5 DIHYDRO 1H PYRROL 3 YLMETHYL)OXOBENZOYL]BENZOFURAN; 2 METHYL 3 [3,5 DIIODO 4 (2,2,5,5 TETRAMETHYL 2,5 DIHYDRO 1H PYRROL 3 YLMETHYL)OXYBENZOYL]BENZOFURAN; 2 METHYL 3 [3,5 DIIODO 4 (2,2,6,6 TETRAMETHYL 1,2,5,6 TETRAHYDROPYRIDIN 4 YLMETHYL)OXYBENZOYL]BENZOFURAN; 2 METHYL 3 [3,5 DIIODO 4 [2 (2,2,6,6 TETRAMETHYLPIPERIDIN 1 YL)ETHYL]OXYBENZOYL]BENZOFURAN; 2 METHYL 3 [3,5 DIIODO 4 [2 N ETHYL N (1 HYDROXY 2,2,5,5 TETRAMETHYL 2,5 DIHYDRO 1H PYRROL 3 YLMETHYL)ETHYL]OXYBENZOYL]BENZOFURAN; 2 METHYL 3 [3,5 DIIODO 4 [2 [N ETHYL N (2,2,5,5 TETRAMETHYL 2,5 DIHYDRO 1H PYRROL 3 YLMETHYL)ETHYL]]OXYBENZOYL]BENZOFURAN; AMINE; AMIODARONE; BENZOFURAZAN DERIVATIVE; ETHER DERIVATIVE; NITROXIDE; PHOSPHATE; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; DRUG PENETRATION; DRUG SCREENING; DRUG SYNTHESIS; EMBRYO; HEART MUSCLE CELL; HEART PERFUSION; LIVER CELL; MITOCHONDRION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; RAT; TOXICITY TESTING;

EID: 14844299446     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.01.028     Document Type: Article

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