A bio-effect directed fractionation study for toxicological and chemical characterization of organic compounds in bottom sediment

Toxicological Sciences

Volumn 84, Issue 1, 2005, Pages 63-72

  Sundberg, Henrik ^a,c   Ishaq, Rasha ^a,b   Åkerman, Gun ^a   Tjärnlund, Ulla ^a   Zebühr, Yngve ^a   Linderoth, Maria ^a   Broman, Dag ^a   Balk, Lennart ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b County Admin Board of Stockholm ^*  (Sweden)

^c Dept of Applied Environ Research ^*  (Sweden)

Author keywords

Blue sac disease; EROD; Fish; Pulp mill; Straight phase HPLC; TIE

Indexed keywords

ANTHRACENE; AROMATIC COMPOUND; AROMATIC HYDROCARBON RECEPTOR; BENZO[A]PYRENE; CHRYSENE; ETHOXYRESORUFIN DEETHYLASE; FLUORANTHENE; HETEROCYCLIC COMPOUND; ORGANIC COMPOUND; PHENANTHRENE; POLYCHLORINATED BIPHENYL; POLYCYCLIC AROMATIC HYDROCARBON; PYRENE;

ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; ENVIRONMENTAL IMPACT; ENZYME ACTIVITY; EXPOSURE; FRACTIONATION; LARVA; NONHUMAN; RAINBOW TROUT; RISK ASSESSMENT; TERATOGENICITY; TOXICITY TESTING; WATER POLLUTION; YOLK SAC; ZYGOTE;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; CYTOCHROME P-450 CYP1A1; GEOLOGIC SEDIMENTS; LARVA; LIVER; ONCORHYNCHUS MYKISS; ORGANIC CHEMICALS; OVUM; POLYCYCLIC HYDROCARBONS, AROMATIC; STRUCTURE-ACTIVITY RELATIONSHIP; TERATOGENS; ULTRAVIOLET RAYS; WATER POLLUTANTS, CHEMICAL;

MYKISS; ONCORHYNCHUS MYKISS; SALMONIDAE;

EID: 14844297027     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfi067     Document Type: Article

References (40)

1. Åkerman, G., and Balk, L. (1995). A reliable and improved methodology to expose fish in the early embryonic stage. Mar. Environ. Res. 39, 155-158.
2. Axelman, J., and Broman, D. (1999). Inventories and fluxes of polychlorinated biphenyls from a contaminated industrial site. Environ. Toxicol. Chem. 18, 1871-1881.
3. Barron, M. G., Carls, A G., Heintz, R., and Rice, S. D. (2004). Evaluation of fish early life-stage toxicity models of chronic embryonic exposures to complex polycyclic aromatic hydrocarbon mixtures. Toxicol. Sci. 78, 60-67.
4. Basu, N., Billiard, S., Fragoso, N., Omoike, A., Tabash, S., Brown, S., and Hodson, P. (2001). Ethoxyresorufin-O-deethylase induction in trout exposed to mixtures of polycyclic aromatic hydrocarbons. Environ. Toxicol. Chem. 20, 1244-1251.
5. Billiard, S. M., Querbach, K., and Hodson, P. V. (1999). Toxicity of retene to early life stages of two freshwater fish species. Environ. Toxicol. Chem. 18, 2070-2077.
6. Black, J. A., Birge, W. J., Westerman, A. G., and Francis, P. C. (1983). Comparative aquatic toxicology of aromatic hydrocarbons. Fundam. Appl. Toxicol. 3, 353-358.
7. Blomqvist, S., and Abrahamsson, B. (1985). An improved Kajak-type gravity core sampler for soft bottom sediments. Schweiz. Z. Hydrol. 47, 81-84.
8. Bols, N. C., Schirmer, K., Joyce, E. M., Dixon, D. G., Greenberg, B. M., and Whyte, J. J. (1999). Ability of polycyclic aromatic hydrocarbons to induce 7-ethoxyresorufin-O-deethylase activity in a trout liver cell line. Ecotoxicol. Environ. Saf. 44, 118-128.
9. Brack, W. (2003). Effect-directed analysis: A promising tool for the identification of organic toxicants in complex mixtures? Anal. Bioanal. Chem. 377, 397-407.
10. Brinkworth, L., Hodson, P., Tabash, S., and Lee, P. (2003). CYP1A induction and blue sac disease in early developmental stages of rainbow trout (Oncorhynchus mykiss) exposed to retene. J. Toxicol. Environ. Health 66A, 627-646.
11. Burgess, R. M. (2000). Characterizing and identifying toxicants in marine waters: A review of marine toxicity identification evaluations (TIEs). Int. J. Environ. Pollut. 13, 2-33.
12. Cantrell, S. M., Joy-Schlezinger, J., Stegeman, J. J., Tillitt, D. E., and Hannink, M. (1998). Correlation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced apoptotic cell death in the embryonic vasculature with embryotoxicity. Toxicol. Appl. Pharmacol. 148, 24-34.
13. Cantrell, S. M., Lutz, L. H., Tillitt, D. E., and Hannink, M. (1996). Embryotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): The embryonic vasculature is a physiological target for TCDD-induced DNA damage and apoptotic cell death in medaka (Orizias latipes). Toxicol. Appl. Pharmacol. 141, 23-34.
14. Carls, M. G., Rice, S. D., and Hose, J. E. (1999). Sensitivity of fish embryos to weathered crude oil: Part I. Low-level exposure during incubation causes malformations, genetic damage, and mortality in larval Pacific herring (Clupea pallasi). Environ. Toxicol. Chem. 18, 481-493.
15. Das, B. S., Reid, S. G., Betts, J. L., and Patrick, K. (1969). Tetrachloro-o-benzoquinone as a component in bleached kraft chlorination effluent toxic to young salmon. J. Fish. Res. Bd. Can. 26, 3055-3067.
16. Denison, M. S., and Heath-Pagliuso, S. (1998). The Ah receptor: A regulator of the biochemical and toxicological actions of structurally diverse chemicals. Bull. Environ. Contam. Toxicol. 61, 557-568.
17. Eastmond, D. A., Booth, G. M., and Lee, M. L. (1984). Toxicity, accumulation, and elimination of polycyclic aromatic sulfur heterocycles in Daphnia magna. Arch. Environ. Contam. Toxicol. 13, 105-111.
18. Engwall, M., Brunström, B., Brewer, A., and Norrgren, L. (1994). Cytochrome P450IA induction by a coplanar PCB, a PAH mixture, and PCB-contaminated sediment extracts following microinjection of rainbow trout sac-fry. Aquat. Toxicol. 30, 311-324.
19. Grimmer, G., Brune, H., Deutsch-Wenzel, R., Dettbarn, G., and Misfeld, J. (1987). Contribution of polycyclic aromatic hydrocarbons and polar polycyclic aromatic compounds to the carcinogenic impact of flue gas condensate from coal-fired residential furnaces evaluatedby implantation into the rat lung. J. Natl. Cancer Inst. 78, 935-942.
20. Guiney, P. D., Smolowitz, R. M., Peterson, R. E., and Stegeman, J. J. (1997). Correlation of 2,3,7,8-tetrachlorodibenzo-p dioxin induction of cytochrome P4501A in vascular endothelium with toxicity in early life stages of lake trout. Toxicol. Appl. Pharmacol. 143, 256-273.
21. Heintz, R. A., Short, J. W., and Rice, S. D. (1999). Sensitivity of fish embryos to weathered crude oil: Part II. Increased mortality of pink salmon (Oncorhynchus gorbuscha) embryos incubating downstream from weathered Exxon Valdez crude oil. Environ. Toxicol. Chem. 18, 494-503.
22. Incardona, J. P., Collier, T. C., and Scholz, N. L. (2004). Defects in cardiac function precede morphological abnormalities in fish embryos exposed to polycyclic aromatic hydrocarbons. Toxicol. Appl. Pharmacol. 196, 191-205.
23. Lamparski, L. L., and Nestrick, T. J. (1980). Determination of tetra, hexa, hepta, and octachlorodibenzo-para-dioxin isomers in particulate samples at parts per trillion levels. Anal. Chem. 52, 2045-2054.
24. Lee, M. L., Vassilaros, D. L., and White, C. M. (1979). Retention indices for programmed-temperature capillary-column gas chromatography of polycyclic aromatic hydrocarbons. Anal. Chem. 51, 768-773.
25. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. (1951). Protein measurement with Folin phenol reagent. J. Biol. Chem. 193, 265-275.
26. Östman, C. E., and Colmsjö, A. L. (1987). Backflush HPLC for the isolation of polycyclic aromatic compounds. A comparative study. Chromatographia 23, 903-908.
27. Pettersen, H., Axelman, J., and Broman, D. (1999). The relative contribution of spatial-, sampling- and analytical variation to the PAH and PCB concentrations in Baltic Sea sediments. Chemosphere 38, 1025-1034.
28. Prough, R. A., Burke, M. D., and Mayer, R. T. (1978). Direct fluorometric methods for measuring mixed-function oxidase activity. In Methods in Enzymology (S. Fleicher and L. Packer, Eds.), vol. L II, part C, pp. 372-377. Academic Press, New York.
29. Rice, S. D., Short, J. W., and Karinen, J. F. (1977). Comparative oil toxicity and comparative animal sensitivity. In Fate and Effects of Petroleum Hydrocarbons in Marine Organisms and Ecosystems (D. A. Wolfe, Ed.), pp. 78-94. Pergamon, Elmsford, NY.
30. Safe, S. (1990). Polychlorinated biphenyls (PCBs), dibenzo- p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). Crit. Rev. Toxicol. 21, 51-88.
31. Schuetzle, D., and Lewtas, J. (1986) Bioassay-directed chemical analysis in environmental research. Anal. Chem. 58, 1060A-1075A.
32. Spitsbergen, J. M., Walker, M. K., Olson, J. R., and Peterson, R. E. (1991). Pathologic alterations in early life stages of lake trout, Salvelinus namaycush, exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin as fertilized eggs. Aquat. Toxicol. 19, 41-71.
33. Sundberg, H., Tjärnlund, U., Åkerman, G., Grunder, K., Ishaq, R., Hammar, T., Broman, D., and Balk, L. (in press). The distribution and relative toxic potential of organic chemicals in a PCB contaminated bay. Mar. Pollut. Bull.
34. Villalobos, S. A., Papoulias, D. M., Meadows, J., Blankenship, A. L., Pastva, S. D., Kannan, K., Hinton, D. E., Tillitt, D. E., and Giesy, J. P. (2000). Toxic responses of medaka, d-rR strain, to polychlorinated naphthalene mixtures after embryonic exposure by in ovo nanoinjection: a partial life-cycle assessment. Environ. Toxicol. Chem. 19, 432-440.
35. Walker, M. K., and Peterson, R. E. (1991). Potencies of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners, relative to 2,3,7,8-tetrachlorodibenzo-p-dioxin, for producing early life stage mortality in rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 21, 219-238.
36. Walker, M. K., Zabel, E. W., Åkerman, G., Balk, L., Wright, P., and Tillitt, D. E. (1996). Chapter Four: Fish egg injection as an alternative exposure route for early life stage toxicity studies. Description of two unique methods. In Techniques in Aquatic Toxicology (G. K. Ostrander, Ed.), pp. 41-72. CRC Press, Boca Raton, FL.
37. Wassenberg, D. M., Swails, E. E., and Di Giulio, R. T. (2002). Effects of single and combined exposures to benzo(a)pyrene and 3,3′4,4′5-pentachlorobiphenyl on EROD activity and development in Fundulus heteroclitus. Mar. Environ. Res. 54, 279-283.
38. Whyte, J. J., Jung, R. E., Schmitt, C. J., and Tillitt, D. E. (2000). Ethoxyresorufin-O-deethylase (EROD) activity in fish as a biomarker of chemical exposure. Crit. Rev. Toxicol. 30, 347-570.
39. Wolf, K. (1969). Blue-sac disease of fish. Fish Disease Leaflet 15, U.S. Fish and Wildlife Service, Kearneysville, WV.
40. Zebühr, Y., Näf, C., Bandh, C., Broman, D., Ishaq, R., and Pettersen, H. (1993). An automated HPLC separation method with 2 coupled columns for the analysis of PCDD/Fs, PCBs and PACs. Chemosphere 27, 1211-1219.