-
1
-
-
2642709177
-
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection
-
HIV Outpatient Study Investigators
-
Palella FJ Jr, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 1998; 338:853-60.
-
(1998)
N Engl J Med
, vol.338
, pp. 853-860
-
-
Palella Jr., F.J.1
Delaney, K.M.2
Moorman, A.C.3
-
2
-
-
0032189850
-
Adverse effects of reverse transcriptase inhibitors: Mitochondrial toxicity as common pathway
-
Brinkman K, ter Hofstede HJ, Burger DM, Smeitink JA, Koopmans PP. Adverse effects of reverse transcriptase inhibitors: mitochondrial toxicity as common pathway. AIDS 1998; 12:1735-44.
-
(1998)
AIDS
, vol.12
, pp. 1735-1744
-
-
Brinkman, K.1
Ter Hofstede, H.J.2
Burger, D.M.3
Smeitink, J.A.4
Koopmans, P.P.5
-
3
-
-
0028990381
-
Mitochondrial toxicity of antiviral drugs
-
Lewis W, Dalakas MC. Mitochondrial toxicity of antiviral drugs. Nat Med 1995; 1:417-22.
-
(1995)
Nat Med
, vol.1
, pp. 417-422
-
-
Lewis, W.1
Dalakas, M.C.2
-
4
-
-
0037999080
-
Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy
-
Nolan D, Hammond E, Martin A, et al. Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy. AIDS 2003; 17:1329-38.
-
(2003)
AIDS
, vol.17
, pp. 1329-1338
-
-
Nolan, D.1
Hammond, E.2
Martin, A.3
-
5
-
-
0037045058
-
Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors
-
Walker UA, Setzer B, Venhoff N. Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors. AIDS 2002; 16:2165-73.
-
(2002)
AIDS
, vol.16
, pp. 2165-2173
-
-
Walker, U.A.1
Setzer, B.2
Venhoff, N.3
-
6
-
-
10644259972
-
Antiretroviral therapy with ddI, d4T or ddC is associated with depletion of mitochondrial DNA in liver
-
Walker UA, Bäuerle J, Laguno M, et al. Antiretroviral therapy with ddI, d4T or ddC is associated with depletion of mitochondrial DNA in liver. Antivir Ther 2003; 8:L15-6.
-
(2003)
Antivir Ther
, vol.8
-
-
Walker, U.A.1
Bäuerle, J.2
Laguno, M.3
-
7
-
-
0025263835
-
2′,3′-Dideoxyinosine (ddI) in patients with the acquired immunodeficiency syndrome or AIDS-related complex: A phase I trial
-
Lambert JS, Seidlin M, Reichman RC, et al. 2′,3′- Dideoxyinosine (ddI) in patients with the acquired immunodeficiency syndrome or AIDS-related complex: a phase I trial. N Engl J Med 1990; 322:1333-40.
-
(1990)
N Engl J Med
, vol.322
, pp. 1333-1340
-
-
Lambert, J.S.1
Seidlin, M.2
Reichman, R.C.3
-
8
-
-
0037076029
-
Changes in mitochondrial DNA as a marker of nucleoside toxicity in HIV-infected patients
-
Cote HC, Brumme ZL, Craib KJ, et al. Changes in mitochondrial DNA as a marker of nucleoside toxicity in HIV-infected patients. N Engl J Med 2002; 346:811-20.
-
(2002)
N Engl J Med
, vol.346
, pp. 811-820
-
-
Cote, H.C.1
Brumme, Z.L.2
Craib, K.J.3
-
9
-
-
0038046118
-
Depletion of mitochondrial DNA in HIV-1-infected patients and its amelioration by antiretroviral therapy
-
Miura T, Goto M, Hosoya N, et al. Depletion of mitochondrial DNA in HIV-1-infected patients and its amelioration by antiretroviral therapy. J Med Virol 2003; 70:497-505.
-
(2003)
J Med Virol
, vol.70
, pp. 497-505
-
-
Miura, T.1
Goto, M.2
Hosoya, N.3
-
10
-
-
0038010608
-
Mitochondrial:nuclear DNA ratios in peripheral blood cells from human immunodeficiency virus (HIV)-infected patients who received selected HIV antiretroviral drug regimens
-
Cote HC, Yip B, Asselin JJ, et al. Mitochondrial:nuclear DNA ratios in peripheral blood cells from human immunodeficiency virus (HIV)-infected patients who received selected HIV antiretroviral drug regimens. J Infect Dis 2003; 187:1972-6.
-
(2003)
J Infect Dis
, vol.187
, pp. 1972-1976
-
-
Cote, H.C.1
Yip, B.2
Asselin, J.J.3
-
11
-
-
10744226254
-
Mitochondrial DNA depletion and respiratory chain enzyme deficiencies are present in peripheral blood mononuclear cells of HIV-infected patients with HAART-related lipodystrophy
-
Miro O, Lopez S, Pedrol E, et al. Mitochondrial DNA depletion and respiratory chain enzyme deficiencies are present in peripheral blood mononuclear cells of HIV-infected patients with HAART-related lipodystrophy. Antivir Ther 2003; 8:333-8.
-
(2003)
Antivir Ther
, vol.8
, pp. 333-338
-
-
Miro, O.1
Lopez, S.2
Pedrol, E.3
-
12
-
-
0037040365
-
Analysis of the mitochondrial DNA genome in the peripheral blood leukocytes of HIV-infected patients with or without lipoatrophy
-
McComsey G, Tan DJ, Lederman M, Wilson E, Wong LJ. Analysis of the mitochondrial DNA genome in the peripheral blood leukocytes of HIV-infected patients with or without lipoatrophy. AIDS 2002; 16:513-8.
-
(2002)
AIDS
, vol.16
, pp. 513-518
-
-
McComsey, G.1
Tan, D.J.2
Lederman, M.3
Wilson, E.4
Wong, L.J.5
-
13
-
-
0036467615
-
Mitochondrial functionality and mitochondrial DNA content in lymphocytes of vertically infected human immunodeficiency virus-positive children with highly active antiretroviral therapy-related lipodystrophy
-
Cossarizza A, Pinti M, Moretti L, et al. Mitochondrial functionality and mitochondrial DNA content in lymphocytes of vertically infected human immunodeficiency virus-positive children with highly active antiretroviral therapy-related lipodystrophy. J Infect Dis 2002; 185:299-305.
-
(2002)
J Infect Dis
, vol.185
, pp. 299-305
-
-
Cossarizza, A.1
Pinti, M.2
Moretti, L.3
-
14
-
-
0037322036
-
Tests for mitochondrial function and DNA: Potentials and pitfalls
-
Cossarizza A. Tests for mitochondrial function and DNA: potentials and pitfalls. Curr Opin Infect Dis 2003; 16:5-10.
-
(2003)
Curr Opin Infect Dis
, vol.16
, pp. 5-10
-
-
Cossarizza, A.1
-
15
-
-
0036171757
-
Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB
-
Maus MV, Thomas AK, Leonard DG, et al. Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB. Nat Biotechnol 2002; 20(2):143-8.
-
(2002)
Nat Biotechnol
, vol.20
, Issue.2
, pp. 143-148
-
-
Maus, M.V.1
Thomas, A.K.2
Leonard, D.G.3
-
16
-
-
0036909464
-
A cell-based artificial antigen-presenting cell coated with anti-CD3 and CD28 antibodies enables rapid expansion and long-term growth of CD4 T lymphocytes
-
Thomas AK, Maus MV, Shalaby WS, June CH, Riley JL. A cell-based artificial antigen-presenting cell coated with anti-CD3 and CD28 antibodies enables rapid expansion and long-term growth of CD4 T lymphocytes. Clin Immunol 2002; 105:259-72.
-
(2002)
Clin Immunol
, vol.105
, pp. 259-272
-
-
Thomas, A.K.1
Maus, M.V.2
Shalaby, W.S.3
June, C.H.4
Riley, J.L.5
-
17
-
-
0242417495
-
Assessment of precision and concordance of quantitative mitochondrial DNA assays: A collaborative international quality assurance study
-
Hammond EL, Sayer D, Nolan D, et al. Assessment of precision and concordance of quantitative mitochondrial DNA assays: a collaborative international quality assurance study. J Clin Virol 2003; 27:97-110.
-
(2003)
J Clin Virol
, vol.27
, pp. 97-110
-
-
Hammond, E.L.1
Sayer, D.2
Nolan, D.3
-
18
-
-
0036640489
-
Exposure to dideoxynucleosides is reflected in lowered mitochondrial DNA in subcutaneous fat
-
Cherry CL, Gahan ME, McArthur JC, Lewin SR, Hoy JF, Wesselingh SL. Exposure to dideoxynucleosides is reflected in lowered mitochondrial DNA in subcutaneous fat. J Acquir Immune Defic Syndr 2002; 30:271-7.
-
(2002)
J Acquir Immune Defic Syndr
, vol.30
, pp. 271-277
-
-
Cherry, C.L.1
Gahan, M.E.2
McArthur, J.C.3
Lewin, S.R.4
Hoy, J.F.5
Wesselingh, S.L.6
-
19
-
-
0030761388
-
Dihydroorotate-ubiquinone oxidoreductase links mitochondria in the biosynthesis of pyrimidine nucleotides
-
Löffler M, Jöckel J, Schuster G, Becker C. Dihydroorotate- ubiquinone oxidoreductase links mitochondria in the biosynthesis of pyrimidine nucleotides. Mol Cell Biochem 1997; 174:125-9.
-
(1997)
Mol Cell Biochem
, vol.174
, pp. 125-129
-
-
Löffler, M.1
Jöckel, J.2
Schuster, G.3
Becker, C.4
-
20
-
-
0034122123
-
Leflunomide: An immunomodulatory drug for the treatment of rheumatoid arthritis and other autoimmune diseases
-
Herrmann ML, Schleyerbach R, Kirschbaum BJ. Leflunomide: an immunomodulatory drug for the treatment of rheumatoid arthritis and other autoimmune diseases. Immunopharmacology 2000; 47:273-89.
-
(2000)
Immunopharmacology
, vol.47
, pp. 273-289
-
-
Herrmann, M.L.1
Schleyerbach, R.2
Kirschbaum, B.J.3
-
21
-
-
0029591467
-
The immunosuppressant leflunomide inhibits lymphocyte proliferation by inhibiting pyrimidine biosynthesis
-
Cherwinski HM, Cohn RG, Cheung P, et al. The immunosuppressant leflunomide inhibits lymphocyte proliferation by inhibiting pyrimidine biosynthesis. J Pharmacol Exp Ther 1995; 275:1043-9.
-
(1995)
J Pharmacol Exp Ther
, vol.275
, pp. 1043-1049
-
-
Cherwinski, H.M.1
Cohn, R.G.2
Cheung, P.3
-
22
-
-
0029811256
-
Mechanism of action of leflunomide: In vivo uridine administration reverses its inhibition of lymphocyte proliferation
-
Silva HT, Cao W, Shorthouse R, Morris RE. Mechanism of action of leflunomide: in vivo uridine administration reverses its inhibition of lymphocyte proliferation. Transplant Proc 1996; 28:3082-4.
-
(1996)
Transplant Proc
, vol.28
, pp. 3082-3084
-
-
Silva, H.T.1
Cao, W.2
Shorthouse, R.3
Morris, R.E.4
-
23
-
-
0036306243
-
Randomized, open-label, comparative trial to evaluate the efficacy and safety of three antiretroviral drug combinations including two nucleoside analogues and nevirapine for previously untreated HIV-1 Infection: The OzCombo 2 study
-
French M, Amin J, Roth N, et al. Randomized, open-label, comparative trial to evaluate the efficacy and safety of three antiretroviral drug combinations including two nucleoside analogues and nevirapine for previously untreated HIV-1 Infection: the OzCombo 2 study. HIV Clin Trials 2002; 3:177-85.
-
(2002)
HIV Clin Trials
, vol.3
, pp. 177-185
-
-
French, M.1
Amin, J.2
Roth, N.3
-
24
-
-
0033502897
-
The ALBI trial: A randomized controlled trial comparing stavudine plus didanosine with zidovudine plus lamivudine and a regimen alternating both combinations in previously untreated patients infected with human immunodeficiency virus
-
Molina JM, Chene G, Ferchal F, et al. The ALBI trial: a randomized controlled trial comparing stavudine plus didanosine with zidovudine plus lamivudine and a regimen alternating both combinations in previously untreated patients infected with human immunodeficiency virus. J Infect Dis 1999; 180:351-8.
-
(1999)
J Infect Dis
, vol.180
, pp. 351-358
-
-
Molina, J.M.1
Chene, G.2
Ferchal, F.3
-
26
-
-
0035823019
-
Direct analysis of mitochondrial toxicity of antiretroviral drugs
-
Foli A, Benvenuto F, Piccinini G, et al. Direct analysis of mitochondrial toxicity of antiretroviral drugs. AIDS 2001; 15:1687-94.
-
(2001)
AIDS
, vol.15
, pp. 1687-1694
-
-
Foli, A.1
Benvenuto, F.2
Piccinini, G.3
-
27
-
-
0037313258
-
Mitochondrial disruption and apoptosis in lymphocytes of an HIV infected patient affected by lactic acidosis after treatment with highly active antiretroviral therapy
-
Tolomeo M, Mancuso S, Todaro M, et al. Mitochondrial disruption and apoptosis in lymphocytes of an HIV infected patient affected by lactic acidosis after treatment with highly active antiretroviral therapy. J Clin Pathol 2003; 56:147-51.
-
(2003)
J Clin Pathol
, vol.56
, pp. 147-151
-
-
Tolomeo, M.1
Mancuso, S.2
Todaro, M.3
-
28
-
-
0041412840
-
Factors associated with mitochondrial dysfunction in circulating peripheral blood lymphocytes from HIV-infected people
-
Polo R, Martinez S, Madrigal P, Gonzalez-Munoz M. Factors associated with mitochondrial dysfunction in circulating peripheral blood lymphocytes from HIV-infected people. J Acquir Immune Defic Syndr 2003; 34:32-6.
-
(2003)
J Acquir Immune Defic Syndr
, vol.34
, pp. 32-36
-
-
Polo, R.1
Martinez, S.2
Madrigal, P.3
Gonzalez-Munoz, M.4
-
29
-
-
12144286268
-
Unexpected CD4 cell count decline in patients receiving didanosine and tenofovir-based regimens despite undetectable viral load
-
Negredo E, Moltó J, Burger D, et al. Unexpected CD4 cell count decline in patients receiving didanosine and tenofovir-based regimens despite undetectable viral load. AIDS 2004; 18:459-63.
-
(2004)
AIDS
, vol.18
, pp. 459-463
-
-
Negredo, E.1
Moltó, J.2
Burger, D.3
-
30
-
-
1642461500
-
Role of purine nucleoside phosphorylase in interactions between 2′,3′-dideoxyinosine and allopurinol, ganciclovir, or tenofovir
-
Ray AS, Olson L, Fridland A. Role of purine nucleoside phosphorylase in interactions between 2′,3′-dideoxyinosine and allopurinol, ganciclovir, or tenofovir. Antimicrob Agents Chemother 2004; 48:1089-95.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 1089-1095
-
-
Ray, A.S.1
Olson, L.2
Fridland, A.3
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