Direct access to CF3-propargyl amines and conversion to difluoromethyl imines

Tetrahedron Letters

Volumn 46, Issue 13, 2005, Pages 2219-2221

  Magueur, Guillaume ^a   Crousse, Benoit ^a   Bonnet Delpon, Danièle ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

CF3 propargyl amines; Difluoromethyl imines; Difluoromethyl propargyl amines; Trifluoromethyl aldimines

Indexed keywords

ACETYLENE; AMINE; FLUORINE DERIVATIVE; IMINE; TOLUENE;

ARTICLE; CHEMICAL REACTION KINETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; TEMPERATURE DEPENDENCE;

EID: 14744302991     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.02.030     Document Type: Article

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18. 4, were filtered and evaporated. The crude product was purified on silica gel to afford the propargyl amine 3a (236 mg, 83%)
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27. Parallel studies have shown that such a deprotonation does not occur from corresponding allyl amine
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