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Volumn 818, Issue 2, 2005, Pages 249-256
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Validation study of a method for assaying DE-310, a macromolecular carrier conjugate containing an anti-tumor camptothecin derivative, and the free drug in human plasma by HPLC and LC/MS/MS
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Author keywords
Camptothecin; DE 310; HPLC; LC MS MS
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Indexed keywords
BIOASSAY;
DERIVATIVES;
PLASMAS;
HUMAN PLASMAS;
MACROMOLECULAR CARRIER CONJUGATES;
PROTEIN PRECIPITATION;
SOLID-PHASE EXTRACTION;
ORGANIC POLYMERS;
ANTINEOPLASTIC AGENT;
CAMPTOTHECIN DERIVATIVE;
DE 310;
DRUG CARRIER;
EXATECAN;
POLYMER;
THERMOLYSIN;
ACCURACY;
ARTICLE;
BLOOD ANALYSIS;
COMPLEX FORMATION;
CONTROLLED STUDY;
DRUG CONJUGATION;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
LIQUID CHROMATOGRAPHY;
MASS SPECTROMETRY;
PRECIPITATION;
PRIORITY JOURNAL;
QUANTITATIVE ANALYSIS;
SOLID PHASE EXTRACTION;
VALIDATION PROCESS;
ANTINEOPLASTIC AGENTS;
CAMPTOTHECIN;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CHROMATOGRAPHY, LIQUID;
DRUG STABILITY;
HUMANS;
MASS SPECTROMETRY;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
THERMOLYSIN;
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EID: 14744296528
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2005.01.005 Document Type: Article |
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Times cited : (2)
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References (10)
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