Determination of MAG-Camptothecin, a new polymer-bound Camptothecin derivative, and free Camptothecin in dog plasma by HPLC with fluorimetric detection

Journal of Pharmaceutical and Biomedical Analysis

Volumn 22, Issue 3, 2000, Pages 505-514

  Fraier, D ^a   Frigerio, E ^a   Brianceschi, G ^a   Casati, M ^a   Benecchi, A ^a   James, C ^a  

^a PFIZER INC   (United States)

Author keywords

Camptothecin; Dog plasma; Fluorimetric detection; HPLC determination; Polymer bound Camptothecin derivative

Indexed keywords

CAMPTOTHECIN; DRUG CARRIER; POLYMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; CALIBRATION; CHROMATOGRAPHY; CONFERENCE PAPER; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG METABOLISM; FLUOROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; TEMPERATURE;

ACRYLAMIDES; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAMPTOTHECIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; FLUOROMETRY; INJECTIONS, INTRAVENOUS; LINEAR MODELS; REPRODUCIBILITY OF RESULTS;

EID: 0034112060     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(99)00315-5     Document Type: Article

References (15)

1. Duncan R. Anti-Cancer Drugs. 3:1992;175-210.
2. Conover C.D., Pedri A., Lee C., Gilbert C.W., Shum K.L., Greenwald R.B. Anti-Cancer Res. 17(5A):1997;3361-3368.
3. Conover C.D., Greenwald R.B., Pedri A., Gilbert C.W., Shum K.L. Cancer Chemother. Pharmacol. 42(5):1998;407-414.
4. Fraier D., Frigerio E., Pianezzola E., Strolin Benedetti M., Cassidy J., Vasey P. J. Pharm. Biom. Anal. 4/5(13):1995;625-633.
5. Vasey P.A., Kaye S.B., Morrison R., Twelve C., Wilson P., Duncan R., Thomson A.H., Murray L.S., Hilditch T.E., Murray T., Burtles S., Fraier D., Frigerio E., Cassidy J. Clin. Cancer Res. 5(1):1999;83-94.
6. A.H. Thomson, P.A. Vasey, L.S. Murray, J. Cassidy, D. Fraier, E. Frigerio, C. Twelves, Population pharmacokinetics in phase I drug development: a phase I study of PK1 in patients with solid tumour, Br. J. Cancer, in press.
7. Fraier D., Cenacchi V., Frigerio E. J. Chromatogr. 797:1998;295-303.
8. Giovanella B.C., Hinz H.R., Kozielski A.J., Stehlin J.S., Silber R., Potmesil M. Cancer Res. 51:1991;3052-3055.
9. Fassberg J., Stella V.J. J. Pharm. Sci. 81(7):1992;676-684.
10. Potmesil M. Cancer Res. 54:1994;1431.
11. Guarino A.M., Anderson J.B., Starkweather D.K., Chignell C.F. Cancer Chemother. Rep. 57(1):1973;125-140.
12. Loh J.-P., Ahmed A.E. J. Chromatogr. 530:1990;367-376.
13. Ahmed F., Vyas V., Saleem A., Li X.G., Zamek R., Cornfield A., Haluska P., Ibrahim N., Rubin E.H., Gupta E. J. Chromatogr. B. 707(1-2):1998;227-233.
14. Warner D.L., Burke T.G. J. Chromatogr. B. 691(1):1997;161-171.
15. US Pharmacopoeia XXII, Pharmacopoeial Convention, Rockville, MD, 1990, pp. 1566-1567.