Hb Tak: A β chain elongation at the end of the β chain, in a Taiwanese

Hemoglobin

Volumn 29, Issue 1, 2005, Pages 65-67

  Shih, Mu Chin ^a   Wu, Kang His ^a   Liu, Su Ching ^a   Chang, Jan Gowth ^a  

^a CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Globin; Hb Tak; Hemoglobin (Hb)

Indexed keywords

ADENINE; AMINO ACID; BETA GLOBIN; CYTOSINE; DINUCLEOTIDE; HEMOGLOBIN VARIANT; UNCLASSIFIED DRUG;

ARTICLE; CASE REPORT; CONTROLLED STUDY; FRAMESHIFT MUTATION; HEMOGLOBIN TAK; HUMAN; RNA TRANSLATION; STOP CODON; TAIWAN;

FEMALE; HEMOGLOBINS, ABNORMAL; HUMANS; MALE; MUTAGENESIS, INSERTIONAL; OPEN READING FRAMES; PROTEIN STRUCTURE, SECONDARY; TAIWAN;

EID: 14644437151     PISSN: 03630269     EISSN: None     Source Type: Journal    
DOI: 10.1081/HEM-200047635     Document Type: Article

References (13)

1. Flatz G, Kinderlerer JL, Kilmartin JV, Lehmann H. Haemoglobin Tak: a variant with additional residues at the end of the β-chains. Lancet 1971; 1(7702):732-733.
2. Tranphaichitr VS, Viprakasit V, Veerakul G, Sanpakit K, Tientadakul P. Homozygous hemoglobin Tak causes symptomatic secondary polycythemia in a Thai boy. J Pediatr Hematol/Oncol 2003; 25(3):261-265.
3. Charoenkwan P, Thanarattanakorn P, Chaovaluksakul S, Sittipreechacharn S, Sae-Tang R, Sanguansermsri T. Hematological and molecular characterization of β-thalassemia/Hb Tak compound heterozygote. SEA J Trop Med Public Health 2003; 34(2):415-419.
4. Fucharoen S, Fucharoen G, Sae-ung N, Sanchaisuriya K, Fukumaki Y. Molecular and hematological characterization of Hb Tak and Hb Pyrgos in Thailand. SEA J Trop Med Public Health 1997; 28(3):110-114.
5. Lie-Injo LE, Randhawa ZI, Ganesan J, Kane J, Peterson D. Hemoglobin Tak in a newborn Malay. Hemoglobin 1977; 1(8):747-757.
6. Lie-Injo LE, Solai A, Ganesan J. Globin chain separation by SDS polyacrylamide gel electrophoresis. Simple screening method for elongated hemoglobin chains. J Chromatogr 1978; 153(1):161-165.
7. Hoyer JD, Wick MJ, Thibodeau SN, Viker KA, Conner R, Fairbanks VF. Hb Tak confirmed by DNA analysis: not expressed as thalassemia in a Hb Tak/Hb E compound heterozygote. Hemoglobin 1998; 22(1):45-52.
8. Cooper DN, Krawczak M. Mechanisms of insertional mutagenesis in human genes causing genetic disease. Hum Genet 1991; 87(4):409-415.
9. Imai K, Lehmann H. The oxygen affinity of Haemoglobin Tak, a variant with an elongated β chain. Biochim Biophys Acta 1975; 412(2):288-294.
10. Bunn HF, Forget BG. Hemoglobin: Molecular, Genetic and Clinical Aspects. Philadelphia: W.B. Saunders Company, 1986.
11. Nagel RL. Disorders of hemoglobin function and stability. In: Steinberg MH, Forget BG, Higgs DR, Nagel RL, eds. Disorders of Hemoglobin. Cambridge: Cambridge University Press, 2001:1155-1194.
12. Chang J-G, Shih M-C, Liu S-C, Peng C-T. Hb Manitoba in Taiwanese: a C→A substitution at codon 102 of the α2-globin gene. Hemoglobin 2001; 25(4):437-739.
13. Chang J-G, Yang T-Y, Perng L-I, Wang NM, Peng C-T, Tsai C-H. Hb Siriraj: a G→A substitution at codon 7 of the β-globin chain creates an MboII cutting site. Hemoglobin 1999; 23(2):197-199.