Hb Manitoba in a Taiwanese family: A C → A substitution at codon 102 of the α2-globin gene

Hemoglobin

Volumn 25, Issue 4, 2001, Pages 437-439

  Chang, J G ^a   Shih, M C ^a   Liu, S C ^a   Chan, W L ^a   Peng, C T ^a  

^a CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2 GLOBIN; ARGININE; GLOBIN; HEMOGLOBIN VARIANT; SERINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CHINA; CODON; GENE MUTATION; HEMOGLOBIN ANALYSIS; HEMOGLOBIN MANITOBA; HETEROZYGOTE; HUMAN; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS;

AMINO ACID SUBSTITUTION; DNA PROBES; ELECTROPHORESIS; FAMILY HEALTH; GLOBINS; HEMOGLOBINS, ABNORMAL; HETEROZYGOTE; HUMANS; POINT MUTATION; POLYMERASE CHAIN REACTION; TAIWAN; VARIATION (GENETICS);

EID: 0035675466     PISSN: 03630269     EISSN: None     Source Type: Journal    
DOI: 10.1081/HEM-100107883     Document Type: Article

References (4)

1. Hemoglobin manitoba: α102 (G9) serine replaced by arginine
2. 2 by high performance liquid chromatography
3. Hb Siriraj: A G → a substitution at codon 7 of the β-globin chain creates an MboII cutting site
4. The differences in quantities of α2- and α1-globin gene variants heterozygotes