메뉴 건너뛰기




Volumn 12, Issue 2, 2005, Pages 114-120

The nitric oxide prodrug, V-PYRRO/NO, protects against cadmium toxicity and apoptosis at the cellular level

Author keywords

Apoptotic resistance; Cadmium; In vitro; Liver cells; V PYRRO NO

Indexed keywords

CADMIUM CHLORIDE; CYTOCHROME P450; LIVER ENZYME; LIVER PROTECTIVE AGENT; NITRIC OXIDE DONOR; O 2 VINYL(PYRROLIDIN 1 YL)DIAZEN 1 IUM 1,2 DIOLATE; PRODRUG; UNCLASSIFIED DRUG;

EID: 14644417105     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.niox.2005.01.005     Document Type: Article
Times cited : (29)

References (33)
  • 1
    • 0028885672 scopus 로고
    • Nitrogen oxide-induced autoprotection in isolated rat hepatocytes
    • Y.M. Kim, H. Bergonia, and J.R. Lancaster Jr. Nitrogen oxide-induced autoprotection in isolated rat hepatocytes FEBS Lett. 374 1995 228 232
    • (1995) FEBS Lett. , vol.374 , pp. 228-232
    • Kim, Y.M.1    Bergonia, H.2    Lancaster Jr., J.R.3
  • 3
    • 0034687778 scopus 로고    scopus 로고
    • Nitric oxide negatively regulates c-Jun N-terminal kinase/stress- activated protein kinase by means of S-nitrosylation
    • H.S. Park, S.H. Huh, M.S. Kim, S.H. Lee, and E.J. Choi Nitric oxide negatively regulates c-Jun N-terminal kinase/stress-activated protein kinase by means of S-nitrosylation Proc. Natl. Acad. Sci. USA 97 2000 14382 14387
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 14382-14387
    • Park, H.S.1    Huh, S.H.2    Kim, M.S.3    Lee, S.H.4    Choi, E.J.5
  • 4
    • 0012707876 scopus 로고    scopus 로고
    • Progress toward clinical application of the nitric oxide-releasing diazeniumdiolates
    • L.K. Keefer Progress toward clinical application of the nitric oxide-releasing diazeniumdiolates Annu. Rev. Pharmacol. Toxicol. 43 2003 585 607
    • (2003) Annu. Rev. Pharmacol. Toxicol. , vol.43 , pp. 585-607
    • Keefer, L.K.1
  • 6
    • 0030918451 scopus 로고    scopus 로고
    • Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-alpha-induced apoptosis and toxicity in the liver
    • J.E. Saavedra, T.R. Billiar, D.L. Williams, Y.M. Kim, S.C. Watkins, and L.K. Keefer Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-alpha-induced apoptosis and toxicity in the liver J. Med. Chem. 40 1997 1947 1954
    • (1997) J. Med. Chem. , vol.40 , pp. 1947-1954
    • Saavedra, J.E.1    Billiar, T.R.2    Williams, D.L.3    Kim, Y.M.4    Watkins, S.C.5    Keefer, L.K.6
  • 7
    • 0036139011 scopus 로고    scopus 로고
    • O(2)-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate protection against d-galactosamine/endotoxin-induced hepatotoxicity in mice: Genomic analysis using microarrays
    • J. Liu, J.E. Saavedra, T. Lu, J.G. Song, J. Clark, M.P. Waalkes, and L.K. Keefer O(2)-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate protection against d-galactosamine/endotoxin-induced hepatotoxicity in mice: genomic analysis using microarrays J. Pharmacol. Exp. Ther. 300 2002 18 25
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 18-25
    • Liu, J.1    Saavedra, J.E.2    Lu, T.3    Song, J.G.4    Clark, J.5    Waalkes, M.P.6    Keefer, L.K.7
  • 8
    • 0037308128 scopus 로고    scopus 로고
    • The nitric oxide donor, V-PYRRO/NO, protects against acetaminophen- induced hepatotoxicity in mice
    • J. Liu, C. Li, M.P. Waalkes, J. Clark, P. Myers, J.E. Saavedra, and L.K. Keefer The nitric oxide donor, V-PYRRO/NO, protects against acetaminophen- induced hepatotoxicity in mice Hepatology 37 2003 324 333
    • (2003) Hepatology , vol.37 , pp. 324-333
    • Liu, J.1    Li, C.2    Waalkes, M.P.3    Clark, J.4    Myers, P.5    Saavedra, J.E.6    Keefer, L.K.7
  • 9
    • 3042688174 scopus 로고    scopus 로고
    • The nitric oxide donor, V-PYRRO/NO, protects against cadmium-induced hepatotocity in mice
    • J. Liu, W. Qu, J.E. Saavedra, and M.P. Waalkes The nitric oxide donor, V-PYRRO/NO, protects against cadmium-induced hepatotocity in mice J. Pharmacol. Exp. Ther. 310 2004 18 24
    • (2004) J. Pharmacol. Exp. Ther. , vol.310 , pp. 18-24
    • Liu, J.1    Qu, W.2    Saavedra, J.E.3    Waalkes, M.P.4
  • 11
    • 0002106617 scopus 로고
    • Evolution, structure and chemical activity of class I metallothionein: An overview
    • K.T. Suzuki N. Imura M. Kimura Birkhauser-Verlag Berlin
    • J.H.R. Kägi Evolution, structure and chemical activity of class I metallothionein: an overview K.T. Suzuki N. Imura M. Kimura Metallothionein III: Biological roles and medical implications 1993 Birkhauser-Verlag Berlin 29 56
    • (1993) Metallothionein III: Biological Roles and Medical Implications , pp. 29-56
    • Kägi, J.H.R.1
  • 12
    • 0026538918 scopus 로고
    • Protective roles of metallothionein and glutathione in hepatotoxicity of cadmium
    • H.M. Chan, and M.G. Cherian Protective roles of metallothionein and glutathione in hepatotoxicity of cadmium Toxicology 72 1992 281 290
    • (1992) Toxicology , vol.72 , pp. 281-290
    • Chan, H.M.1    Cherian, M.G.2
  • 13
    • 0032953164 scopus 로고    scopus 로고
    • Metallothionein: An intracellular protein to protect against cadmium toxicity
    • C.D. Klaassen, J. Liu, and S. Choudhuri Metallothionein: an intracellular protein to protect against cadmium toxicity Annu. Rev. Pharmacol. Toxicol. 39 1999 267 294
    • (1999) Annu. Rev. Pharmacol. Toxicol. , vol.39 , pp. 267-294
    • Klaassen, C.D.1    Liu, J.2    Choudhuri, S.3
  • 14
    • 0021333270 scopus 로고
    • Relative in vitro affinity of hepatic metallothionein for metals
    • M.P. Waalkes, M.J. Harvey, and C.D. Klaassen Relative in vitro affinity of hepatic metallothionein for metals Toxicol. Lett. 20 1984 33 39
    • (1984) Toxicol. Lett. , vol.20 , pp. 33-39
    • Waalkes, M.P.1    Harvey, M.J.2    Klaassen, C.D.3
  • 15
    • 0030033203 scopus 로고    scopus 로고
    • Evidence that nitric oxide enhances cadmium toxicity by displacing the metal from metallothionein
    • R.R. Misra, J.F. Hochadel, G.T. Smith, J.C. Cook, M.P. Waalkes, and D.A. Wink Evidence that nitric oxide enhances cadmium toxicity by displacing the metal from metallothionein Chem. Res. Toxicol. 9 1996 326 332
    • (1996) Chem. Res. Toxicol. , vol.9 , pp. 326-332
    • Misra, R.R.1    Hochadel, J.F.2    Smith, G.T.3    Cook, J.C.4    Waalkes, M.P.5    Wink, D.A.6
  • 16
    • 0035961216 scopus 로고    scopus 로고
    • Nitric oxide induces metallothionein (MT) gene expression apparently by displacing zinc bound to MT
    • K. Katakai, J. Liu, K. Nakajima, L.K. Keefer, and M.P. Waalkes Nitric oxide induces metallothionein (MT) gene expression apparently by displacing zinc bound to MT Toxicol. Lett. 119 2001 103 108
    • (2001) Toxicol. Lett. , vol.119 , pp. 103-108
    • Katakai, K.1    Liu, J.2    Nakajima, K.3    Keefer, L.K.4    Waalkes, M.P.5
  • 17
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Z. Xia, M. Dickens, J. Raingeaud, R.J. Davis, and M.E. Greenberg Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis Science 270 1995 1326 1331
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 18
    • 0036200868 scopus 로고    scopus 로고
    • Acquisition of apoptotic resistance in arsenic-induced malignant transformation: Role of the JNK signal transduction pathway
    • W. Qu, C.D. Bortner, T. Sakurai, M.J. Hobson, and M.P. Waalkes Acquisition of apoptotic resistance in arsenic-induced malignant transformation: role of the JNK signal transduction pathway Carcinogenesis 23 2002 151 159
    • (2002) Carcinogenesis , vol.23 , pp. 151-159
    • Qu, W.1    Bortner, C.D.2    Sakurai, T.3    Hobson, M.J.4    Waalkes, M.P.5
  • 19
    • 0037278520 scopus 로고    scopus 로고
    • Short-term depletion of catalase suppresses cadmium-elicited c-Jun N-terminal kinase activation and apoptosis: Role of protein phosphatases
    • S.M. Chuang, I.C. Wang, Y.S. Hwua, and J.L. Yang Short-term depletion of catalase suppresses cadmium-elicited c-Jun N-terminal kinase activation and apoptosis: role of protein phosphatases Carcinogenesis 24 2003 7 15
    • (2003) Carcinogenesis , vol.24 , pp. 7-15
    • Chuang, S.M.1    Wang, I.C.2    Hwua, Y.S.3    Yang, J.L.4
  • 20
    • 1842714965 scopus 로고    scopus 로고
    • Suppression of cadmium-induced JNK/p38 activation and HSP70 family gene expression by LL-Z1640-2 in NIH3T3 cells
    • N. Sugisawa, M. Matsuoka, T. Okuno, and H. Igisu Suppression of cadmium-induced JNK/p38 activation and HSP70 family gene expression by LL-Z1640-2 in NIH3T3 cells Toxicol. Appl. Pharmacol. 196 2004 206 214
    • (2004) Toxicol. Appl. Pharmacol. , vol.196 , pp. 206-214
    • Sugisawa, N.1    Matsuoka, M.2    Okuno, T.3    Igisu, H.4
  • 21
    • 0032552997 scopus 로고    scopus 로고
    • Activation of c-Jun NH2-terminal kinase (JNK/SAPK) in LLC-PK1 cells by cadmium
    • M. Matsuoka, and H. Igisu Activation of c-Jun NH2-terminal kinase (JNK/SAPK) in LLC-PK1 cells by cadmium Biochem. Biophys. Res. Commun. 251 1998 527 532
    • (1998) Biochem. Biophys. Res. Commun. , vol.251 , pp. 527-532
    • Matsuoka, M.1    Igisu, H.2
  • 22
    • 0033923816 scopus 로고    scopus 로고
    • Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium
    • S.M. Chuang, I.C. Wang, and J.L. Yang Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium Carcinogenesis 21 2000 1423 1432
    • (2000) Carcinogenesis , vol.21 , pp. 1423-1432
    • Chuang, S.M.1    Wang, I.C.2    Yang, J.L.3
  • 23
    • 0030885707 scopus 로고    scopus 로고
    • Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression
    • C.Q. Zhao, M.R. Young, B.A. Diwan, T.P. Coogan, and M.P. Waalkes Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression Proc. Natl. Acad. Sci. USA 94 1997 10907 10912
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10907-10912
    • Zhao, C.Q.1    Young, M.R.2    Diwan, B.A.3    Coogan, T.P.4    Waalkes, M.P.5
  • 24
    • 0020455632 scopus 로고
    • Evaluation of the Cd/hemoglobin affinity assay for the rapid determination of metallothionein in biological tissues
    • D.L. Eaton, and B.F. Toal Evaluation of the Cd/hemoglobin affinity assay for the rapid determination of metallothionein in biological tissues Toxicol. Appl. Pharmacol. 66 1982 134 142
    • (1982) Toxicol. Appl. Pharmacol. , vol.66 , pp. 134-142
    • Eaton, D.L.1    Toal, B.F.2
  • 25
    • 0035198895 scopus 로고    scopus 로고
    • Induction of apoptosis in cells by cadmium: Quantitative negative correlation between basal or induced metallothionein concentration and apoptotic rate
    • R. Shimoda, T. Nagamine, H. Takagi, M. Mori, and M.P. Waalkes Induction of apoptosis in cells by cadmium: quantitative negative correlation between basal or induced metallothionein concentration and apoptotic rate Toxicol. Sci. 64 2001 208 215
    • (2001) Toxicol. Sci. , vol.64 , pp. 208-215
    • Shimoda, R.1    Nagamine, T.2    Takagi, H.3    Mori, M.4    Waalkes, M.P.5
  • 26
    • 0037954792 scopus 로고    scopus 로고
    • Inactivation of zinc finger transcription factors provides a mechanism for a gene regulatory role of nitric oxide
    • K.D. Kroncke, and C. Carlberg Inactivation of zinc finger transcription factors provides a mechanism for a gene regulatory role of nitric oxide FASEB J. 14 2000 166 173
    • (2000) FASEB J. , vol.14 , pp. 166-173
    • Kroncke, K.D.1    Carlberg, C.2
  • 28
    • 0029955623 scopus 로고    scopus 로고
    • Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases
    • Y.Y. Lo, J.M. Wong, and T.F. Cruz Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases J. Biol. Chem. 271 1996 15703 15707
    • (1996) J. Biol. Chem. , vol.271 , pp. 15703-15707
    • Lo, Y.Y.1    Wong, J.M.2    Cruz, T.F.3
  • 29
    • 0032484219 scopus 로고    scopus 로고
    • Nitric oxide and N-acetylcysteine inhibit the activation of mitogen-activated protein kinases by angiotensin II in rat cardiac fibroblasts
    • D. Wang, X. Yu, and P. Brecher Nitric oxide and N-acetylcysteine inhibit the activation of mitogen-activated protein kinases by angiotensin II in rat cardiac fibroblasts J. Biol. Chem. 273 1998 33027 33034
    • (1998) J. Biol. Chem. , vol.273 , pp. 33027-33034
    • Wang, D.1    Yu, X.2    Brecher, P.3
  • 30
    • 0029807306 scopus 로고    scopus 로고
    • Differential activation of mitogen-activated protein kinases by nitric oxide-related species
    • H.M. Lander, A.T. Jacovina, R.J. Davis, and J.M. Tauras Differential activation of mitogen-activated protein kinases by nitric oxide-related species J. Biol. Chem. 271 1996 19705 19709
    • (1996) J. Biol. Chem. , vol.271 , pp. 19705-19709
    • Lander, H.M.1    Jacovina, A.T.2    Davis, R.J.3    Tauras, J.M.4
  • 31
    • 0033559903 scopus 로고    scopus 로고
    • Overexpression of protein kinase C isoforms protects RAW 264.7 macrophages from nitric oxide-induced apoptosis: Involvement of c-Jun N-terminal kinase/stress-activated protein kinase, p38 kinase, and CPP-32 protease pathways
    • C.D. Jun, C.D. Oh, H.J. Kwak, H.O. Pae, J.C. Yoo, B.M. Choi, J.S. Chun, R.K. Park, and H.T. Chung Overexpression of protein kinase C isoforms protects RAW 264.7 macrophages from nitric oxide-induced apoptosis: involvement of c-Jun N-terminal kinase/stress-activated protein kinase, p38 kinase, and CPP-32 protease pathways J. Immunol. 162 1999 3395 3401
    • (1999) J. Immunol. , vol.162 , pp. 3395-3401
    • Jun, C.D.1    Oh, C.D.2    Kwak, H.J.3    Pae, H.O.4    Yoo, J.C.5    Choi, B.M.6    Chun, J.S.7    Park, R.K.8    Chung, H.T.9
  • 32
    • 0034723251 scopus 로고    scopus 로고
    • Selenite inhibits the c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) through a thiol redox mechanism
    • H.S. Park, E. Park, M.S. Kim, K. Ahn, I.Y. Kim, and E.J. Choi Selenite inhibits the c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) through a thiol redox mechanism J. Biol. Chem. 275 2000 2527 2531
    • (2000) J. Biol. Chem. , vol.275 , pp. 2527-2531
    • Park, H.S.1    Park, E.2    Kim, M.S.3    Ahn, K.4    Kim, I.Y.5    Choi, E.J.6
  • 33
    • 0039137646 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinases in S-nitrosoglutathione-induced macrophage apoptosis
    • D. Callsen, and B. Brune Role of mitogen-activated protein kinases in S-nitrosoglutathione-induced macrophage apoptosis Biochemistry 38 1999 2279 2286
    • (1999) Biochemistry , vol.38 , pp. 2279-2286
    • Callsen, D.1    Brune, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.