Evaluation of a pharmaceutical care program to improve adherence to antiretroviral therapy;Evaluación de un programa de atención farmacéutica dirigido a mejorar la adherencia al tratamiento antirretroviral

Farmacia Hospitalaria

Volumn 28, Issue 6 SUPPL. 1, 2004, Pages 19-26

  Codina Jané, Carles ^a   Tuset Creus, M ^a   Ibarra Barrueta, O ^b   Delgado Sanchez O ^c   Morancho Echevarria O ^a   Garcia Diaz B ^d  

^a HOSPITAL CLÍNIC   (Spain)

^b HOSPITAL DE GALDAKAO   (Spain)

^c HOSPITAL UNIVERSITARIO SON ESPASES   (Spain)

^d HOSPITAL SEVERO OCHOA   (Spain)

Author keywords

Adherence; Antiretroviral therapy; Human immunodefficiency virus; Pharmaceutical care

Indexed keywords

ANTIRETROVIRUS AGENT; CD4 ANTIGEN; LAMIVUDINE; STAVUDINE; ZIDOVUDINE;

ADULT; AGED; ARTICLE; CLINICAL OBSERVATION; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; HEALTH PROGRAM; HETEROSEXUALITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTRAVENOUS DRUG ABUSE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PATIENT COMPLIANCE; PHARMACY; PRACTICE GUIDELINE; PROFESSIONAL PRACTICE; PROSPECTIVE STUDY; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; TREATMENT OUTCOME; VIRUS LOAD;

ADULT; AGED; ANTI-RETROVIRAL AGENTS; FEMALE; HUMANS; MALE; MIDDLE AGED; PATIENT COMPLIANCE; PHARMACY SERVICE, HOSPITAL; PROGRAM EVALUATION; PROSPECTIVE STUDIES;

EID: 14644416626     PISSN: 11306343     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Palella FJ Jr., Delaney KM, Moorman AC, Loveless MO, Fuhrer J, Satten GA, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 1998; 338: 853-60.
2. Chesney MA, Ickovics J, Hecht FM, Sikipa G, Rabkin J. Adherence: a necessity for successful HIV combination therapy. AIDS 1999; 13: S271-8.
3. Miro JM, Antela A, Arrizabalaga J, Clotet B, Gatell JM, Guerra L, et al. Recomendaciones de GESIDA/Plan Nacional sobre el Sida respecto al tratamiento antirretrovírico en pacientes adultos infectados por el virus de la inmunodeficiencia humana en el año 2000 (II). Enferm Infecc Microbiol Clin 2000; 18: 396-412.
4. Moreno A, Perez-Elias MJ, Casado JL, Muñoz V, Antela A, Dronda F, et al. Effectiveness and pitfalls of initial highly active antiretroviral therapy in HIV-infected patients in routine clinical practice. Antivir Ther 2000; 5: 243-8.
5. Molto J, Gutiérrez F. Resistance to protease inhibitors in HIV patients experiencing virologic failure despite adherence to antiretroviral therapy. Am Clin Lab 2001; 20: 23-5.
6. Bangsberg DR, Hecht FM, Charlebois ED, Zolopa AR, Holodniy M, Sheiner L, et al. Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population. AIDS 2000; 14: 357-66.
7. Bartlett JA. Addressing the challenges of adherence. J Acquir Immune Defic Syndr 2002; 29: S2-10.
8. Chesney MA, Morin M, Sherr L. Adherence to HIV combination therapy. Soc Sci Med 2000; 50: 1599-605.
9. Chesney MA. Factors affecting adherence to antiretroviral therapy. Clin Infect Dis 2000; 30 (Supl. 2): S171-6.
10. Walsh JC, Home R, Dalton M, Burgess AP, Gazzard BG. Reasons for non-adherence to antiretroviral therapy: patients' perspectives provide evidence of multiple causes. AIDS Care 2001; 13: 709-20.
11. Knobel H, Carmona A, Grau S, Pedro-Botet J, Diez A. Adherence and effectiveness of highly active antiretroviral therapy. Arch Intern Med 1998; 158: 1953.
12. Rodríguez-Rosado R, Jiménez-Nacher I, Soriano V, Antón P, González-Lahoz J. Virological failure and adherence to antiretroviral therapy in HIV-infected patients. AIDS 1998; 12: 1112-3.
13. López-Suárez A, Fernández-Gutiérrez DA, Pérez-Guzmán E, Girón-González JA. Adherence to the antiretroviral treatment in asymptomatic HIV-infected patients. AIDS 1998; 12: 685-6.
14. Paterson DL, Swindells S, Mohr J, Brester M, Vergis EN, Squier C, et al. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med 2000; 133: 21-30.
15. Valenti WM. HAART is cost-effective and improves outcomes. AIDS Read 2001; 11: 260-2.
16. Knobel H, Codina C, Miro JM, Carmona A, García B, Antela A, et al. Recomendaciones de GESIDA/SEFH/PNS para mejorar la adherencia al tratamiento antirretroviral. Enferm Infecc Microbiol Clin 2000; 18: 27-39.
17. Knobel H, Alonso J, Casado JL, Collazos J, González J, Ruiz I, et al. Validation of a simplified medication adherence questionnaire in a large cohort of HIV-infected patients: the GEEMA Study. AIDS 2002; 16: 605-13.
18. Mannheimer S, Friedland G, Matts J, Child C, Chesney M. The consistency of adherence to antiretroviral therapy predicts biologic outcomes for human immunodeficiency virus-infected persons in clinical trials. Clin Infect Dis 2002; 34: 1115-21.
19. Riera M, La Fuente LL, Castanyer B, Puigventos F, Villalonga C, Ribas MA, et al. Adherencia al tratamiento antirretroviral medida a través del recuento de medicación y niveles plasmáticos. Variables asociadas a una mala adherencia. Med Clin (Barc) 2002; 119: 286-92.
20. Bentz L, Pradier C, Morin M, Spire B, Rebillon M, Souville M, et al. Efficacy of a counseling intervention on adherence to HAART: results of a french prospective controlled study. XIV International AIDS conference 2002; Abstract WePeB5867.
21. Haynes RB, Montague P, Oliver T, McKibbon KA, Brouwers MC, Kanani R. Interventions for helping patients to follow prescriptions for medications. Cochrane Database Syst Rev 2000; CD000011.
22. Codina C, Martínez M, Tuset M, Del Cacho E, Martín MT, Miro JM, et al. Comparación de tres métodos de cálculo de adherencia en pacientes con tratamiento antirretroviral. Enferm Infecc Microbiol Clin 2002; 20: 484-90.
23. Arici C, Ripamonti D, Maggiolo F, Rizzi M, Finazzi MG, Pezzotti P, et al. Factors associated with the failure of HIV-positive persons to return for scheduled medical visits. HIV Clin Trials 2002; 3: 52-7.
24. Stone VE. Strategies for optimizing adherence to highly active antiretroviral therapy: lessons from research and clinical practice. Clin Infect Dis 2001; 33: 865-72.
25. Roberts KJ. Physician-Patient Relationships, Patient Satisfaction, and Antiretroviral Medication Adherence Among HIV-Infected Adults Attending a Public Health Clinic. AIDS Patient Care STDS 2002; 16: 43-50.
26. Raboud JM, Harris M, Rae S, Montaner JS. Impact of adherence on duration of virological suppression among patients receiving combination antiretroviral therapy. HIV Med 2002; 3: 118-24.
27. Tuldra A, Fumaz CR, Ferrer MJ, Bayes R, Amo A, Balague M, et al. Prospective randomized two-arm controlled study to determine the efficacy of a specific intervention to improve long-term adherence to highly active antiretroviral therapy. J Acquir Immune Defic Syndr 2000; 25: 221-8.
28. Knobel H, Carmona A, López JL, Gimeno JL, Saballs P, González A, et al. Adherencia al tratamiento antirretroviral de gran actividad: impacto de una intervención de asesoramiento individualizada. Enferm Infecc Microbiol Clin 1999; 17: 78-81.
29. Bond WS, Hussar DA. Detection methods and strategies for improving medication compliance. Am J Hosp Pharm 1991; 48: 1978-88.