Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors

Journal of Cell Science

Volumn 118, Issue 3, 2005, Pages 497-504

  Depuydt, Bart ^a   Van Loo, Geert ^a,b   Vandenabeele, Peter ^a   Declercq, Wim ^a  

^a GHENT UNIVERSITY   (Belgium)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY EMBL   (Italy)

Author keywords

Apoptosis; Caspase; Cytotoxic T cells; FADD; TNF receptor

Indexed keywords

BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 8; CASPASE 8 INHIBITOR; CYTOKINE RESPONSE MODIFIER A; DEATH RECEPTOR; FAS ASSOCIATED DEATH DOMAIN PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; TUMOR NECROSIS FACTOR RECEPTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DELETION MUTANT; DOWN REGULATION; ENZYME INHIBITION; GENE OVEREXPRESSION; HYBRIDOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; CASPASE 8; CASPASES; CELL SURVIVAL; CYCLOHEXIMIDE; CYSTEINE PROTEINASE INHIBITORS; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HUMANS; HYBRIDOMAS; MICE; MUTATION; RATS; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; T-LYMPHOCYTES; TNF RECEPTOR-ASSOCIATED FACTOR 2; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 14644414800     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.01640     Document Type: Article

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