A theoretical DFT investigation of the lysozyme mechanism: Computational evidence for a covalent intermediate pathway

Proteins: Structure, Function and Genetics

Volumn 59, Issue 1, 2005, Pages 118-130

  Bottoni, Andrea ^a   Miscione, Gian Pietro ^a   De Vivo, Marco ^b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

DFT investigation; Enzyme mechanism; Glycosidase; Lysozyme

Indexed keywords

ALDEHYDE; CARBON; GLYCOSIDASE; LYSOZYME; PEPTIDOGLYCAN;

ARTICLE; CATALYSIS; CHEMICAL BOND; CHIRALITY; CRYSTAL STRUCTURE; DENSITY FUNCTIONAL THEORY; ELECTRICITY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME STRUCTURE; MATHEMATICAL ANALYSIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; SOLVENT EFFECT;

CATALYSIS; DISACCHARIDES; ELECTROSTATICS; KINETICS; MODELS, MOLECULAR; MURAMIDASE; SUBSTRATE SPECIFICITY;

EID: 14644390850     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.20396     Document Type: Article

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