Aging and subcellular localization of m2 muscarinic autoreceptor in basalocortical neurons in vivo

Neurobiology of Aging

Volumn 26, Issue 7, 2005, Pages 1061-1072

  Décossas, Marion ^a   Doudnikoff, Évelyne ^a   Bloch, Bertrand ^a   Bernard, Véronique ^a,b  

^a CNRS   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Acetylcholine; Aging; Autoreceptor; Immunohistochemistry; Receptor localization

Indexed keywords

MUSCARINIC M2 RECEPTOR; PRESYNAPTIC RECEPTOR; SUBSTANCE P RECEPTOR;

AGING; ANIMAL CELL; ARTICLE; BRAIN CELL; CELL MEMBRANE; CHOLINERGIC SYSTEM; CHOLINERGIC TRANSMISSION; CONTROLLED STUDY; CYTOPLASM; DENDRITE; FRONTAL CORTEX; MALE; NONHUMAN; OLIVARY NUCLEUS; PERIKARYON; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN LOCALIZATION; RAT; RECEPTOR DENSITY; SOMATOSENSORY CORTEX; VARICOSIS;

EID: 14644388788     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2004.09.007     Document Type: Article

References (50)

1. D.M. Araujo Effects of aging on nicotinic and muscarinic autoreceptor function in the rat brain: relationship to presynaptic cholinergic markers and binding sites J Neurosci 10 9 1990 3069 3078
2. R.T. Bartus On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis Exp Neurol 163 2 2000 495 529
3. V. Bernard Subcellular redistribution of m2 muscarinic acetylcholine receptors in striatal interneurons in vivo after acute cholinergic stimulation J Neurosci 18 23 1998 10207 10218
4. V. Bernard, A.I. Levey, and B. Bloch Regulation of the subcellular distribution of m4 muscarinic acetylcholine receptors in striatal neurons in vivo by the cholinergic environment: evidence for regulation of cell surface receptors by endogenous and exogenous stimulation J Neurosci 19 23 1999 10237 10249
5. A. Biegon Aging and brain cholinergic muscarinic receptor subtypes: an autoradiographic study in the rat Neurobiol Aging 10 4 1989 305 310
6. A. Birthelmer Presynaptic regulation of neurotransmitter release in the cortex of aged rats with differential memory impairments Pharmacol Biochem Behav 75 1 2003 147 162
7. L.W. Chen Cholinergic neurons expressing substance P receptor (NK(1)) in the basal forebrain of the rat: a double immunocytochemical study Brain Res 904 1 2001 161 166
8. J.M. Conner Nontropic actions of neurotrophins: subcortical nerve growth factor gene delivery reverses age-related degeneration of primate cortical cholinergic innervation Proc Natl Acad Sci USA 98 4 2001 1941 1946
9. J. Dai Impaired axonal transport of cortical neurons in Alzheimer's disease is associated with neuropathological changes Brain Res 948 1-2 2002 138 144
10. S. De Lacalle Reduced retrograde labelling with fluorescent tracer accompanies neuronal atrophy of basal forebrain cholinergic neurons in aged rats Neuroscience 75 1 1996 19 27
11. S. de Lacalle, I. Iraizoz, and L. Ma Gonzalo Differential changes in cell size and number in topographic subdivisions of human basal nucleus in normal aging Neuroscience 43 2/3 1991 445 456
12. M. Decossas, B. Bloch, and V. Bernard Trafficking of the muscarinic m2 autoreceptor in cholinergic basalocortical neurons in vivo: differential regulation of plasma membrane receptor availability and intraneuronal localization in acetylcholinesterase-deficient and -inhibited mice J Comp Neurol 462 3 2003 302 314
13. G.L. Dunbar Hippocampal choline acetyltransferase activity correlates with spatial learning in aged rats Brain Res 604 1-2 1993 266 272
14. S. Dunnett Cholinergic grafts, memory and ageing Trends Neurosci 14 8 1991 371 376
15. K. Elrod, and J.J. Buccafusco Correlation of the amnestic effects of nicotinic antagonists with inhibition of regional brain acetylcholine synthesis in rats J Pharmacol Exp Ther 258 2 1991 403 409
16. C. Eva Nerve growth factor modulates the expression of muscarinic cholinergic receptor messenger RNA in telencephalic neuronal cultures from newborn rat brain Brain Res Mol Brain Res 14 4 1992 344 351
17. C.E. Finch Neuron atrophy during aging: programmed or sporadic? Trends Neurosci 16 3 1993 104 110
18. P.T. Francis The cholinergic hypothesis of Alzheimer's disease: a review of progress J Neurol Neurosurg Psychiatr 66 2 1999 137 147
19. M. Gallagher, and P.J. Colombo Ageing: the cholinergic hypothesis of cognitive decline Curr Opin Neurobiol 5 2 1995 161 168
20. E.M. Jagoda, K. Shimoji, L. Ravasi, M. Yamada, J. Gomeza, and J. Wess Regional brain uptake of the muscarinic ligand, [18F]FP-TZTP, is greatly decreased in M2 receptor knockout mice but not in M1, M3 and M4 receptor knockout mice Neuropharmacology 44 5 2003 653 661
21. C. Lebrun A comparison of the working memory performances of young and aged mice combined with parallel measures of testing and drug-induced activations of septo-hippocampal and nbm-cortical cholinergic neurones Neurobiol Aging 11 5 1990 515 521
22. A.I. Levey Light and electron microscopic study of m2 muscarinic acetylcholine receptor in the basal forebrain of the rat J Comp Neurol 351 3 1995 339 356
23. A.I. Levey Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies J Neurosci 11 10 1991 3218 3226
24. W.H. Ludlam mRNAs encoding muscarinic and substance P receptors in cultured sympathetic neurons are differentially regulated by LIF or CNTF Dev Biol 164 2 1994 528 539
25. V. Luine, and M. Hearns Spatial memory deficits in aged rats: contributions of the cholinergic system assessed by ChAT Brain Res 523 2 1990 321 324
26. M.M. Mesulam Some cholinergic themes related to Alzheimer's disease: synaptology of the nucleus basalis, location of m2 receptors, interactions with amyloid metabolism, and perturbations of cortical plasticity J Physiol (Paris) 92 3-4 1998 293 298
27. H. Moore Potassium, but not atropine-stimulated cortical acetylcholine efflux, is reduced in aged rats Neurobiol Aging 17 4 1996 565 571
28. E.J. Mufson Distribution and retrograde transport of trophic factors in the central nervous system: functional implications for the treatment of neurodegenerative diseases Prog Neurobiol 57 4 1999 451 484
29. N. Narang In situ determination of M1 and M2 muscarinic receptor binding sites and mRNAs in young and old rat brains Mech Ageing Dev 78 3 1995 221 239
30. P.A. Newhouse Age-related effects of the nicotinic antagonist mecamylamine on cognition and behavior Neuropsychopharmacology 10 2 1994 93 107
31. O.G. Nilsson, and F.H. Gage Anticholinergic sensitivity in the aging rat septohippocampal system as assessed in a spatial memory task Neurobiol Aging 14 5 1993 487 497
32. A. Nordberg, I. Alafuzoff, and B. Winblad Nicotinic and muscarinic subtypes in the human brain: changes with aging and dementia J Neurosci Res 31 1 1992 103 111
33. E.K. Perry Alteration in nicotine binding sites in Parkinson's disease. Lewy body dementia and Alzheimer's disease: possible index of early neuropathology Neuroscience 64 2 1995 385 395
34. T.A. Podruchny In vivo muscarinic 2 receptor imaging in cognitively normal young and older volunteers Synapse 48 1 2003 39 44
35. R. Quirion Facilitation of acetylcholine release and cognitive performance by an M(2)-muscarinic receptor antagonist in aged memory-impaired J Neurosci 15 2 1995 1455 1462
36. W.R. Reenstra, M. Yaar, and B.A. Gilchrest Aging affects epidermal growth factor receptor phosphorylation and traffic kinetics Exp Cell Res 227 2 1996 252 255
37. S.T. Rouse, T.M. Thomas, and A.I. Levey Muscarinic acetylcholine receptor subtype, m2: diverse functional implications of differential synaptic localization Life Sci 60 13/14 1997 1031 1038
38. D.B. Rye Cortical projections arising from the basal forebrain: a study of cholinergic and noncholinergic components employing combined retrograde tracing and immunohistochemical localization of choline acetyltransferase Neuroscience 13 3 1984 627 643
39. K. Semba, and H.C. Fibiger Organization of central cholinergic systems Prog Brain Res 79 1989 37 63
40. R. Shigemoto Immunocytochemical localization of rat substance P receptor in the striatum Neurosci Lett 153 2 1993 157 160
41. M.L. Smith, R.M. Booze, and Cholinergic and GABAergic neurons in the nucleus basalis region of young and aged rats Neuroscience 67 3 1995 679 688
42. T.D. Smith, M. Gallagher, and F.M. Leslie Cholinergic binding sites in rat brain: analysis by age and cognitive status Neurobiol Aging 16 2 1995 161 173
43. J. Stemmelin Immunohistochemical and neurochemical correlates of learning deficits in aged rats Neuroscience 96 2 2000 275 289
44. A.V. Terry Jr., and J.J. Buccafusco The cholinergic hypothesis of age and Alzheimer's disease-related cognitive deficits: recent challenges and their implications for novel drug development J Pharmacol Exp Ther 306 3 2003 821 827
45. A.V. Terry Jr., J.J. Buccafusco, and W.J. Jackson Scopolamine reversal of nicotine enhanced delayed matching-to-sample performance in monkeys Pharmacol Biochem Behav 45 4 1993 925 929
46. P. Turrini Cholinergic nerve terminals establish classical synapses in the rat cerebral cortex: synaptic pattern and age-related atrophy Neuroscience 105 2 2001 277 285
47. M.T. Vilaro, J.M. Palacios, and G. Mengod Multiplicity of muscarinic autoreceptor subtypes? Comparison of the distribution of cholinergic cells and cells containing mRNA for five subtypes of muscarinic receptors in the rat brain Brain Res Mol Brain Res 21 1-2 1994 30 46
48. M.T. Vilaro Muscarinic M2 receptor mRNA expression and receptor binding in cholinergic and non-cholinergic cells in the rat brain: a correlative study using in situ hybridization histochemistry and receptor autoradiography Neuroscience 47 2 1992 367 393
49. B. Vitiello Cognitive and behavioral effects of cholinergic, dopaminergic, and serotonergic blockade in humans Neuropsychopharmacology 16 1 1997 15 24
50. W. Zhang Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice J Neurosci 22 5 2002 1709 1717