Plasma concentrations and effects of oral methylprednisolone are considerably increased by itraconazole

Clinical Pharmacology and Therapeutics

Volumn 64, Issue 4, 1998, Pages 363-368

  Varis, Tiina ^b   Kaukonen, Kirsi Maija ^b   Kivistö, Kari T ^b   Neuvonen, Pertti J ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; CYTOCHROME P450; GLUCOCORTICOID; ITRACONAZOLE; METHYLPREDNISOLONE;

ADULT; AGED; ANTIFUNGAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; CORTICOSTEROID THERAPY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG METABOLISM; FEMALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; IMMUNOSUPPRESSIVE TREATMENT; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADMINISTRATION, ORAL; ADULT; ANTI-INFLAMMATORY AGENTS; ANTIFUNGAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROSS-OVER STUDIES; CYTOCHROME P-450 ENZYME SYSTEM; DOUBLE-BLIND METHOD; FEMALE; GLUCOCORTICOIDS; HALF-LIFE; HUMANS; ITRACONAZOLE; MALE; METHYLPREDNISOLONE; MIXED FUNCTION OXYGENASES; REFERENCE VALUES;

EID: 0031660264     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9236(98)90066-2     Document Type: Article

References (16)

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