Microreactor-based reaction optimization in organic chemistry - Glycosylation as a challenge

Chemical Communications

Volumn , Issue 5, 2005, Pages 578-580

  Ratner, Daniel M ^a   Murphy, Edward R ^b   Jhunjhunwala, Manish ^b   Snyder, Daniel A ^a   Jensen, Klavs F ^b   Seeberger, Peter H ^a,c  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

SILICON;

ARTICLE; CONTINUOUS FLOW REACTOR; GLYCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MICROFLUIDICS; ORGANIC CHEMISTRY; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; REACTION TIME; TEMPERATURE; THERMAL CONDUCTIVITY; ULTRAVIOLET SPECTROSCOPY;

EID: 14544291001     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/b414503h     Document Type: Article

References (14)

1. J. Lehmann, in Carbohydrates: Structure and Biology, Thieme, Stuttgart, 1998, p. 1-45.
2. For review, see: K. Toshima and K. Tatsuta, Chem. Rev., 1993, 120, 1503; T. Nukada, A. Berces, M. Z. Zgierski and D. M. Whitfield, J. Am. Chem. Soc., 1998, 120, 13291.
3. For review, see: K. Toshima and K. Tatsuta, Chem. Rev., 1993, 120, 1503; T. Nukada, A. Berces, M. Z. Zgierski and D. M. Whitfield, J. Am. Chem. Soc., 1998, 120, 13291.
4. R. Carlson, Design and Optimization in Organic Synthesis, Elsevier Science: Amsterdam, New York, 1992.
5. K. Jähnisch, V. Hessel, H. Löwe and M. Baerns, Angew. Chem. Int. Ed., 2004, 43, 406; H. Pennemann, P. Watts, S. J. Haswell, V. Hessel and H. Löwe, Org. Process Res. Dev., 2004, 8, 422; P. D. I. Fletcher, S. J. Haswell, E. Pombo-Villar, B. H. Warrington, P. Watts, S. Y. F. Wong and X. Zhang, Tetrahedron, 2002, 58, 4735.
6. K. Jähnisch, V. Hessel, H. Löwe and M. Baerns, Angew. Chem. Int. Ed., 2004, 43, 406; H. Pennemann, P. Watts, S. J. Haswell, V. Hessel and H. Löwe, Org. Process Res. Dev., 2004, 8, 422; P. D. I. Fletcher, S. J. Haswell, E. Pombo-Villar, B. H. Warrington, P. Watts, S. Y. F. Wong and X. Zhang, Tetrahedron, 2002, 58, 4735.
7. K. Jähnisch, V. Hessel, H. Löwe and M. Baerns, Angew. Chem. Int. Ed., 2004, 43, 406; H. Pennemann, P. Watts, S. J. Haswell, V. Hessel and H. Löwe, Org. Process Res. Dev., 2004, 8, 422; P. D. I. Fletcher, S. J. Haswell, E. Pombo-Villar, B. H. Warrington, P. Watts, S. Y. F. Wong and X. Zhang, Tetrahedron, 2002, 58, 4735.
8. M. Schilling, W. Nigge, A. Rudzinski, A. Neyer and R. Hergenröder, Lab. Chip, 2004, 4, 220; R. J. Jackman, T. M. Floyd, R. Ghodssi, M. A. Schmidt and K. F. Jensen, J. Micromech. Microeng., 2001, 11, 263; H. Lu, M. A. Schmidt and K. F. Jensen, Lab. Chip., 2001, 1, 22.
9. M. Schilling, W. Nigge, A. Rudzinski, A. Neyer and R. Hergenröder, Lab. Chip, 2004, 4, 220; R. J. Jackman, T. M. Floyd, R. Ghodssi, M. A. Schmidt and K. F. Jensen, J. Micromech. Microeng., 2001, 11, 263; H. Lu, M. A. Schmidt and K. F. Jensen, Lab. Chip., 2001, 1, 22.
10. M. Schilling, W. Nigge, A. Rudzinski, A. Neyer and R. Hergenröder, Lab. Chip, 2004, 4, 220; R. J. Jackman, T. M. Floyd, R. Ghodssi, M. A. Schmidt and K. F. Jensen, J. Micromech. Microeng., 2001, 11, 263; H. Lu, M. A. Schmidt and K. F. Jensen, Lab. Chip., 2001, 1, 22.
11. K. F. Jensen, Chem. Eng. Sci., 2001, 56, 293.
12. M. W. Losey, R. J. Jackman, S. L. Firebaugh, M. A. Schmidt and K. F. Jensen, J. Microelectromech Sys., 2002, 11, 709.
13. P. Fügedi, A. Lipták and P. N. Neszmélyi, Carbohydr. Res., 1982, 107, C5; A. Vasella, C. Witzig, C. Waldraff, P. Uhlmann, K. Briner, B. Bernet, L. Panza and R. Husi, Helv. Chim. Acta, 1993, 76, 2847.
14. P. Fügedi, A. Lipták and P. N. Neszmélyi, Carbohydr. Res., 1982, 107, C5; A. Vasella, C. Witzig, C. Waldraff, P. Uhlmann, K. Briner, B. Bernet, L. Panza and R. Husi, Helv. Chim. Acta, 1993, 76, 2847.