Disturbance of hepatic and intestinal microcirculation in experimental liver cirrhosis

World Journal of Gastroenterology

Volumn 11, Issue 6, 2005, Pages 846-849

  Maksan, Sasa Marcel ^a   Ryschich, Eduard ^b   Ülger, Zilfi ^b   Gebhard, Martha Maria ^b   Schmidt, Jan ^b  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Liver; Liver cirrhosis; Microcirculatory; Small intestine

Indexed keywords

ANTITHROMBIN III; CARBON TETRACHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; ENDOTHELIUM; EXPERIMENTAL MODEL; FEEDING; INFLAMMATION; INTESTINE BLOOD FLOW; LEUKOCYTE; LIVER CIRCULATION; LIVER CIRRHOSIS; MALE; MICROCIRCULATION; MICROSCOPY; NONHUMAN; PORTAL HYPERTENSION; RAT; RAT STRAIN; SMALL INTESTINE MUCOSA; VIDEORECORDING;

EID: 14544277510     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i6.846     Document Type: Article

References (25)

1. Borzio M, Salerno F, Piantoni L, Cazzaniga M, Angeli P, Bissoli F, Boccia S, Colloredo-Mels G, Corigliano P, Fornaciari G, Marenco G, Pistara R, Salvagnini M, Sangiovanni A. Bacterial infection in patients with advanced cirrhosis: A multicenter prospective study. Dig Liver Dis 2001; 33: 41-48
2. Llovet JM, Bartoli R, March F, Planas R, Vinado B, Cabre E, Arnal J, Coll P, Ausina V, Gassull MA. Translocated intestinal bacteria cause spontaneous bacterial peritonitis in cirrhotic rats: molecular epidemiologic evidence. J Hepatol 1998; 28: 307-313
3. Parlesak A, Schafer C, Schutz T, Bode JC, Bode C. Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol-induced liver disease. J Hepatol 2000; 32: 742-747
4. Pascual S, Such J, Esteban A, Zapater P, Casellas JA, Aparicio JR, Girona E, Gutierrez A, Carnices F, Palazon JM, Sola-Vera J, Perez-Mateo M. Intestinal permeability is increased in patients with advanced cirrhosis. Hepatogastroenterology 2003; 50: 1482-1486
5. Arroyo V. Pathophysiology, diagnosis and treatment of ascites in cirrhosis. Ann Hepatol 2002; 1: 72-79
6. Varin F, Huet PM. Hepatic microcirculation in the perfused cirrhotic rat liver. J Clin Invest 1985; 76: 1904-1912
7. Shibayama Y. On the pathogenesis of portal hypertension in cirrhosis of the liver. Liver 1988; 8: 95-99
8. Ekataksin W, Kaneda K. Liver microvascular architecture: an insight into the pathophysiology of portal hypertension. Semin Liver Dis 1999; 19: 359-382
9. Horie Y, Wolf R, Miyasaka M, Anderson DC, Granger DN. Leukocyte adhesion and hepatic microvascular responses to intestinal ischemia/reperfusion in rats. Gastroenterology 1996; 111: 666-673
10. Ruh J, Ryschich E, Secchi A, Gebhard MM, Glaser F, Klar E, Herfarth C. Measurement of blood flow of the villi in rat small intestine with FITC-labeled erythrocytes. Microvasc Res 1998; 56 62-69
11. Proctor E, Chatamra K. Standardized micronodular cirrhosis in the rat. Eur Surg Res 1984; 16: 182-186
12. Mc Lean EK, Mc Lean AE, Sutton PM. Instant cirrhosis: An improved method for producing cirrhosis of the liver in rats by simultaneous administration of carbon tetrachloride and phenobarbitane. Br J Exp Pathol 1969; 50: 502-506
13. Menger MD, Marzi I, Messmer K. In vivo fluorescence microscopy for quantitative analysis of the hepatic microcirculation in hamsters and rats. Eur Surg Res 1991; 23: 158-169
14. Zeintl H, Sack FU, Intaglietta M, Messmer K. Computer assisted leukocyte adhesion measurement in intravital microscopy. Int J Microcirc Clin Exp 1989; 8: 293-302
15. Gross JF, Aroesty J. Mathematical models of capillary flow: A critical review. Biorheology 1972; 9: 225-264
16. Foreman MG, Mannino DM, Moss M. Cirrhosis as a risk factor for sepsis and death. Analysis of the national hospital discharge survey. Chest 2003; 124: 1016-1020
17. Shellman RG, Fulkerson WJ, De Long E, Piantadosi CA. Prognosis of patients with cirrhosis and chronic liver disease admitted to the medical intensive care unit. Crit Care Med 1988; 16: 671-678
18. Vorobioff J, Bredfeldt JE, Groszmann RJ. Increased blood flow through portal system in cirrhotic rats. Gastroenterology 1984; 87: 1120-1126
19. Sherman IA, Pappas SC, Fisher MM. Hepatic microvascular changes associated with development of liver fibrosis and cirrhosis. Am J Physiol 1990; 258: H460-H465
20. Chen YC, Gines P, Yang J, Summer SN, Falk S, Russell NS, Schrier RW. Increased vascular heme oxygenase-1 expression contributes to arterial vasodilation in experimental cirrhosis in rats. Hepatology 2004; 39: 1075-1087
21. 4-induced cirrhosis. J Surg Res 2003; 113: 172-178
22. Okajima K, Uchiba M. The anti-inflammatory properties of antithrombin III: New therapeutic implications. Semin Thromb Hemost 1998; 24: 27-32
23. Maksan SM, Maksan MO, Gebhard MM, Herfarth C, Klar E. Reduction of hepatic reperfusion injury by antithrombin III and aprotinin. Transplant Int 2000; 13(Suppl 1): S562-S564
24. Ben-Ari Z, Osman E, Hutton RA, Burroughs AK. Disseminated intravascular coagulation in liver cirrhosis: Fact or fiction? Am J Gastroenterol 1999; 94: 2977-2982
25. Scherer R, Kabatnik M, Erhard J, Peters J. The influence of antithrombin III (ATIII) substitution to supranormal activities on systemic procoagulant turnover in patients with end-stage chronic liver disease. Intensive Care Med 1997; 23: 1150-1158