-
1
-
-
0029127881
-
Therapy of bovine ocular squamous-cell carcinoma with local doses of interleukin-2: 67% Complete regressions after 20 months of follow-up
-
Den Otter W, Hill FW, Klein WR, et al. Therapy of bovine ocular squamous-cell carcinoma with local doses of interleukin-2: 67% complete regressions after 20 months of follow-up. Cancer Immunol Immunother. 1995;41:10-14.
-
(1995)
Cancer Immunol Immunother
, vol.41
, pp. 10-14
-
-
Den Otter, W.1
Hill, F.W.2
Klein, W.R.3
-
3
-
-
0024832082
-
Immunotherapy of mice with a large burden of disseminated lymphoma with low-dose interleukin 2
-
Maas RA, Dullens HF, De Jong WH, et al. Immunotherapy of mice with a large burden of disseminated lymphoma with low-dose interleukin 2. Cancer Res. 1989;49:7037-7040.
-
(1989)
Cancer Res
, vol.49
, pp. 7037-7040
-
-
Maas, R.A.1
Dullens, H.F.2
De Jong, W.H.3
-
4
-
-
0030465005
-
Evaluation of the antitumor activity of the interleukin-12/pulse interleukin-2 combination
-
Wigginton JM, Komschlies KL, Green JE, et al. Evaluation of the antitumor activity of the interleukin-12/pulse interleukin-2 combination. Ann N Y Acad Sci. 1996;795:434-439.
-
(1996)
Ann N Y Acad Sci
, vol.795
, pp. 434-439
-
-
Wigginton, J.M.1
Komschlies, K.L.2
Green, J.E.3
-
5
-
-
0027239503
-
Antitumor and antimetastatic activity of interleukin 12 against murine tumors
-
Brunda MJ, Luistro L, Warrier RR, et al. Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J Exp Med. 1993;178:1223-1230.
-
(1993)
J Exp Med
, vol.178
, pp. 1223-1230
-
-
Brunda, M.J.1
Luistro, L.2
Warrier, R.R.3
-
6
-
-
0031410650
-
Signaling from the IL-2 receptor to the nucleus
-
Lin JX, Leonard WJ. Signaling from the IL-2 receptor to the nucleus. Cytokine Growth Factor Rev. 1997;8:313-332.
-
(1997)
Cytokine Growth Factor Rev
, vol.8
, pp. 313-332
-
-
Lin, J.X.1
Leonard, W.J.2
-
7
-
-
0022811060
-
Malignant clonal expansion of large granular lymphocytes with a Leu- 11+, Leu-7-surface phenotype: In vitro responsiveness of malignant cells to recombinant human interleukin 2
-
Koizumi S, Seki H, Tachinami T, et al. Malignant clonal expansion of large granular lymphocytes with a Leu- 11+, Leu-7-surface phenotype: in vitro responsiveness of malignant cells to recombinant human interleukin 2. Blood. 1986;68:1065-1073.
-
(1986)
Blood
, vol.68
, pp. 1065-1073
-
-
Koizumi, S.1
Seki, H.2
Tachinami, T.3
-
8
-
-
0020635291
-
Lymphokine-activated killer cell phenomenon. III. Evidence that IL-2 is sufficient for direct activation of peripheral blood lymphocytes into lymphokine-activated killer cells
-
Grimm EA, Robb RJ, Roth JA, et al. Lymphokine-activated killer cell phenomenon. III. Evidence that IL-2 is sufficient for direct activation of peripheral blood lymphocytes into lymphokine-activated killer cells. J Exp Med. 1983;158:1356-1361.
-
(1983)
J Exp Med
, vol.158
, pp. 1356-1361
-
-
Grimm, E.A.1
Robb, R.J.2
Roth, J.A.3
-
9
-
-
0029592623
-
Phenotypic and functional characteristics of in vivo-induced interleukin-12-activated killer cells
-
Nishimura T, Watanabe K, Lee U, et al. Phenotypic and functional characteristics of in vivo-induced interleukin-12-activated killer cells. Immunol Lett. 1995;48:167-174.
-
(1995)
Immunol Lett
, vol.48
, pp. 167-174
-
-
Nishimura, T.1
Watanabe, K.2
Lee, U.3
-
10
-
-
0031001042
-
Enhanced induction of very late antigen 4/lymphocyte function-associated antigen 1-dependent T-cell migration to tumor sites following administration of interleukin 12
-
Ogawa M, Tsutsui T, Zou JP, et al. Enhanced induction of very late antigen 4/lymphocyte function-associated antigen 1-dependent T-cell migration to tumor sites following administration of interleukin 12. Cancer Res. 1997;57:2216-2222.
-
(1997)
Cancer Res
, vol.57
, pp. 2216-2222
-
-
Ogawa, M.1
Tsutsui, T.2
Zou, J.P.3
-
11
-
-
0036181115
-
Interleukin-12 augments cytolytic activity of peripheral blood mononuclear cells against autologous lung cancer cells in combination with IL-2
-
Hiraki A, Kiura K, Yamane H, et al. Interleukin-12 augments cytolytic activity of peripheral blood mononuclear cells against autologous lung cancer cells in combination with IL-2. Lung Cancer. 2002;35:329-333.
-
(2002)
Lung Cancer
, vol.35
, pp. 329-333
-
-
Hiraki, A.1
Kiura, K.2
Yamane, H.3
-
12
-
-
0032934504
-
Perforin-dependent NK cell cytotoxicity is sufficient for anti-metastatic effect of IL-12
-
Kodama T, Takeda K, Shimozato O, et al. Perforin-dependent NK cell cytotoxicity is sufficient for anti-metastatic effect of IL-12. Eur J Immunol. 1999;29:1390-1396.
-
(1999)
Eur J Immunol
, vol.29
, pp. 1390-1396
-
-
Kodama, T.1
Takeda, K.2
Shimozato, O.3
-
13
-
-
0034045677
-
Relative contribution of NK and NKT cells to the anti-metastatic activities of IL-12
-
Takeda K, Hayakawa Y, Atsuta M, et al. Relative contribution of NK and NKT cells to the anti-metastatic activities of IL-12. Int Immunol. 2000;12:909-914.
-
(2000)
Int Immunol
, vol.12
, pp. 909-914
-
-
Takeda, K.1
Hayakawa, Y.2
Atsuta, M.3
-
14
-
-
0030613856
-
Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors
-
Cui J, Shin T, Kawano T, et al. Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors. Science. 1997;278:1623-1626.
-
(1997)
Science
, vol.278
, pp. 1623-1626
-
-
Cui, J.1
Shin, T.2
Kawano, T.3
-
15
-
-
0028910222
-
Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: Differential use of Janus family tyrosine kinases by IL-2 and IL-12
-
Bacon CM, McVicar DW, Ortaldo JR, et al. Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12. J Exp Med. 1995;181:399-404.
-
(1995)
J Exp Med
, vol.181
, pp. 399-404
-
-
Bacon, C.M.1
McVicar, D.W.2
Ortaldo, J.R.3
-
16
-
-
0026605457
-
IL-12 receptor. II. Distribution and regulation of receptor expression
-
Desai BB, Quinn PM, Wolitzky AG, et al. IL-12 receptor. II. Distribution and regulation of receptor expression. J Immunol. 1992;148:3125-3132.
-
(1992)
J Immunol
, vol.148
, pp. 3125-3132
-
-
Desai, B.B.1
Quinn, P.M.2
Wolitzky, A.G.3
-
17
-
-
0028278950
-
Second signal activity of IL-12 on the proliferation and IL-2R expression of T helper cell-1 clone
-
Yanagida T, Kato T, Igarashi O, et al. Second signal activity of IL-12 on the proliferation and IL-2R expression of T helper cell-1 clone. J Immunol. 1994;152:4919-4928.
-
(1994)
J Immunol
, vol.152
, pp. 4919-4928
-
-
Yanagida, T.1
Kato, T.2
Igarashi, O.3
-
18
-
-
0025819340
-
Induction of interferon gamma production by natural killer cell stimulatory factor: Characterization of the responder cells and synergy with other inducers
-
Chan SH, Perussia B, Gupta JW, et al. Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers. J Exp Med. 1991;173:869-879.
-
(1991)
J Exp Med
, vol.173
, pp. 869-879
-
-
Chan, S.H.1
Perussia, B.2
Gupta, J.W.3
-
19
-
-
0033561559
-
The functional synergy between IL-12 and IL-2 involves p38 mitogen-activated protein kinase and is associated with the augmentation of STAT serine phosphorylation
-
Gollob JA, Schnipper CP, Murphy EA, et al. The functional synergy between IL-12 and IL-2 involves p38 mitogen-activated protein kinase and is associated with the augmentation of STAT serine phosphorylation. J Immunol. 1999;162:4472-4481.
-
(1999)
J Immunol
, vol.162
, pp. 4472-4481
-
-
Gollob, J.A.1
Schnipper, C.P.2
Murphy, E.A.3
-
20
-
-
0030766971
-
Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production
-
Leonard JP, Sherman ML, Fisher GL, et al. Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production. Blood. 1997;90:2541-2548.
-
(1997)
Blood
, vol.90
, pp. 2541-2548
-
-
Leonard, J.P.1
Sherman, M.L.2
Fisher, G.L.3
-
21
-
-
0027226015
-
Effects of IL-12 on the generation of cytotoxic activity in human CD8+ T lymphocytes
-
Mehrotra PT, Wu D, Crim JA, et al. Effects of IL-12 on the generation of cytotoxic activity in human CD8+ T lymphocytes. J Immunol. 1993;151:2444-2452.
-
(1993)
J Immunol
, vol.151
, pp. 2444-2452
-
-
Mehrotra, P.T.1
Wu, D.2
Crim, J.A.3
-
22
-
-
0029096189
-
IL-12 synergizes with IL-2 to induce lymphokine-activated cytotoxicity and perforin and granzyme gene expression in fresh human NK cells
-
DeBlaker-Hohe DF, Yamauchi A, Yu CR, et al. IL-12 synergizes with IL-2 to induce lymphokine-activated cytotoxicity and perforin and granzyme gene expression in fresh human NK cells. Cell Immunol. 1995;165:33-43.
-
(1995)
Cell Immunol
, vol.165
, pp. 33-43
-
-
DeBlaker-Hohe, D.F.1
Yamauchi, A.2
Yu, C.R.3
-
24
-
-
0023173660
-
Immune reactivity in SL2 lymphoma-bearing mice compared with SL2-immunized mice
-
De Weger RA, Wilbrink B, Moberts RM, et al. Immune reactivity in SL2 lymphoma-bearing mice compared with SL2-immunized mice. Cancer Immunol Immunother. 1987;24:25-36.
-
(1987)
Cancer Immunol Immunother
, vol.24
, pp. 25-36
-
-
De Weger, R.A.1
Wilbrink, B.2
Moberts, R.M.3
-
25
-
-
0029557327
-
Role of IL12 in the development of human Th1 type cells
-
Romagnani S, Manetti R, Annunziato F, et al. Role of IL12 in the development of human Th1 type cells. Res Immunol. 1995;146:452-460.
-
(1995)
Res Immunol
, vol.146
, pp. 452-460
-
-
Romagnani, S.1
Manetti, R.2
Annunziato, F.3
-
26
-
-
0028885598
-
Interleukin-12 synergizes with interleukin-2 to generate lymphokine-activated killer activity in peripheral.blood mononuclear cells cultured in ovarian cancer ascitic fluid
-
Barton DP, Blanchard DK, Duan C, et al. Interleukin-12 synergizes with interleukin-2 to generate lymphokine-activated killer activity in peripheral.blood mononuclear cells cultured in ovarian cancer ascitic fluid. J Soc Gynecol Investig. 1995;2:762-771.
-
(1995)
J Soc Gynecol Investig
, vol.2
, pp. 762-771
-
-
Barton, D.P.1
Blanchard, D.K.2
Duan, C.3
-
27
-
-
0038408925
-
Mechanisms of macrophage cytotoxicity in IL-2 and IL-12 mediated tumour regression
-
Masztalerz A, Van Rooijen N, Den Otter W, et al. Mechanisms of macrophage cytotoxicity in IL-2 and IL-12 mediated tumour regression. Cancer Immunol Immunother. 2003;52:235-242.
-
(2003)
Cancer Immunol Immunother
, vol.52
, pp. 235-242
-
-
Masztalerz, A.1
Van Rooijen, N.2
Den Otter, W.3
-
28
-
-
0032146581
-
Characterization of a novel subset of CD8(+) T cells that expands in patients receiving interleukin-12
-
Gollob JA, Schnipper CP, Orsini E, et al. Characterization of a novel subset of CD8(+) T cells that expands in patients receiving interleukin-12. J Clin Invest. 1998;102:561-575.
-
(1998)
J Clin Invest
, vol.102
, pp. 561-575
-
-
Gollob, J.A.1
Schnipper, C.P.2
Orsini, E.3
-
29
-
-
0031571742
-
Administration of IL-12 induces a CD3+ CD4- CD8- B220+ lymphoid population capable of eliciting cytolysis against Fas-positive tumor cells
-
Tsutsui T, Mu J, Ogawa M, et al. Administration of IL-12 induces a CD3+ CD4- CD8- B220+ lymphoid population capable of eliciting cytolysis against Fas-positive tumor cells. J Immunol. 1997;159:2599-2605.
-
(1997)
J Immunol
, vol.159
, pp. 2599-2605
-
-
Tsutsui, T.1
Mu, J.2
Ogawa, M.3
|