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Volumn 198, Issue 3, 2004, Pages 410-421

Multiple anticancer effects of blocking MEK-ERK signaling in hepatocellular carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANTISENSE OLIGONUCLEOTIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; SURVIVIN;

EID: 1442335098     PISSN: 10727515     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jamcollsurg.2003.10.004     Document Type: Article
Times cited : (90)

References (26)
  • 1
    • 0033999104 scopus 로고    scopus 로고
    • Genetic alterations in liver carcinogenesis: Implications for new preventive and therapeutic strategies
    • Feo F., Pascale R.M., Simile M.M., et al. Genetic alterations in liver carcinogenesis implications for new preventive and therapeutic strategies. Crit Rev Oncog. 11:2000;19-62.
    • (2000) Crit Rev Oncog , vol.11 , pp. 19-62
    • Feo, F.1    Pascale, R.M.2    Simile, M.M.3
  • 2
    • 0028977847 scopus 로고    scopus 로고
    • Receptor-tyrosine-kinase and GBγ mediated MAPK kinase activation by a common signaling pathway
    • Van Biesen T., Hawes B.E., Luttrell D.K., et al. Receptor-tyrosine- kinase and GBγ mediated MAPK kinase activation by a common signaling pathway. Nature. 376:1996;781-784.
    • (1996) Nature , vol.376 , pp. 781-784
    • Van Biesen, T.1    Hawes, B.E.2    Luttrell, D.K.3
  • 3
    • 0027283659 scopus 로고
    • Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAPK kinase kinase (p45mapkk) in fibroblasts
    • Lenormand P., Sardet C., Pages G., et al. Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAPK kinase kinase (p45mapkk) in fibroblasts. J Cell Biol. 122:1993;1079-1088.
    • (1993) J Cell Biol , vol.122 , pp. 1079-1088
    • Lenormand, P.1    Sardet, C.2    Pages, G.3
  • 4
    • 0027422609 scopus 로고
    • MAP kinases: Activation, subcellular localization and role in the control of cell activation
    • Lenormand P., Ages G., Sardet C., et al. MAP kinases activation, subcellular localization and role in the control of cell activation. Adv Second Messenger Phosphoprotein Res. 28:1993;237-244.
    • (1993) Adv Second Messenger Phosphoprotein Res , vol.28 , pp. 237-244
    • Lenormand, P.1    Ages, G.2    Sardet, C.3
  • 5
    • 0027165150 scopus 로고
    • The mitogen activated protein kinase signal transduction pathway
    • Davis R.J. The mitogen activated protein kinase signal transduction pathway. J Biol Chem. 268:1993;14553-14556.
    • (1993) J Biol Chem , vol.268 , pp. 14553-14556
    • Davis, R.J.1
  • 6
    • 0028141496 scopus 로고
    • Transformation of mammalian cells by constitutively active MAP kinase kinase
    • Mansouer S.J., Mathen W.T., Harmann A.S., et al. Transformation of mammalian cells by constitutively active MAP kinase kinase. Science. 265:1994;966-970.
    • (1994) Science , vol.265 , pp. 966-970
    • Mansouer, S.J.1    Mathen, W.T.2    Harmann, A.S.3
  • 7
    • 0030927326 scopus 로고    scopus 로고
    • Activation of the JNK pathway is essential for transformation by the Met oncogene
    • Rodriguez G.A., Park M., Schlessinger J. Activation of the JNK pathway is essential for transformation by the Met oncogene. EMBO J. 16:1997;2634-2645.
    • (1997) EMBO J , vol.16 , pp. 2634-2645
    • Rodriguez, G.A.1    Park, M.2    Schlessinger, J.3
  • 8
    • 0029827324 scopus 로고    scopus 로고
    • A comparative study of the hepatic mitogen-activated protein kinase and Jun-NH2-terminal kinase pathways in the late gestation fetal rat
    • Boylan J.M., Gruppuso P.A. A comparative study of the hepatic mitogen-activated protein kinase and Jun-NH2-terminal kinase pathways in the late gestation fetal rat. Cell Growth Differ. 7:1996;1261-1269.
    • (1996) Cell Growth Differ , vol.7 , pp. 1261-1269
    • Boylan, J.M.1    Gruppuso, P.A.2
  • 9
    • 0030823407 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase pathway can mediate growth inhibition and proliferation in smooth muscle cells
    • Bornfeldt KE, Campbell JS, Koyama H, et al. The mitogen-activated protein kinase pathway can mediate growth inhibition and proliferation in smooth muscle cells. J Clin Invest 100:875-885
    • J Clin Invest , vol.100 , pp. 875-885
    • Bornfeldt, K.E.1    Campbell, J.S.2    Koyama, H.3
  • 11
    • 0031561127 scopus 로고    scopus 로고
    • Increased MAPK expression and activity in primary human hepatocellular carcinoma
    • Schmidt C.M., McKillop I.H., Cahill P.A., Sitzmann J.V. Increased MAPK expression and activity in primary human hepatocellular carcinoma. Bioch Biophy Res Comm. 236:1997;54-58.
    • (1997) Bioch Biophy Res Comm , vol.236 , pp. 54-58
    • Schmidt, C.M.1    McKillop, I.H.2    Cahill, P.A.3    Sitzmann, J.V.4
  • 12
    • 17344372847 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase/extracellular signal-regulated protein kinase in human hepatocellular carcinoma
    • Ito Y., Sasaki Y., Horimoto M., et al. Activation of mitogen-activated protein kinase/extracellular signal-regulated protein kinase in human hepatocellular carcinoma. Hepatology. 27:1998;951-958.
    • (1998) Hepatology , vol.27 , pp. 951-958
    • Ito, Y.1    Sasaki, Y.2    Horimoto, M.3
  • 13
    • 20644463704 scopus 로고    scopus 로고
    • Altered Gq/G11 guanine nucleotide regulatory protein expression in a rat model of hepatocellular carcinoma: Role in mitogenesis
    • Schmidt C.M., McKillop I.H., Cahill P.A., Sitzmann J.V. Altered Gq/G11 guanine nucleotide regulatory protein expression in a rat model of hepatocellular carcinoma role in mitogenesis. Hepatology. 29:1999;371-378.
    • (1999) Hepatology , vol.29 , pp. 371-378
    • Schmidt, C.M.1    McKillop, I.H.2    Cahill, P.A.3    Sitzmann, J.V.4
  • 14
    • 0033034522 scopus 로고    scopus 로고
    • Enhanced Gi-protein mediated mitogenesis following chronic ethanol exposure in a rat model of experimental hepatocellular carcinoma
    • McKillop I.H., Nilesh V., Schmidt C.M., et al. Enhanced Gi-protein mediated mitogenesis following chronic ethanol exposure in a rat model of experimental hepatocellular carcinoma. Hepatology. 29:1999;412-420.
    • (1999) Hepatology , vol.29 , pp. 412-420
    • McKillop, I.H.1    Nilesh, V.2    Schmidt, C.M.3
  • 15
    • 0032774153 scopus 로고    scopus 로고
    • Inhibitory guanine nucleotide regulatory protein activation of mitogen activated protein kinase in hepatocellular carcinoma
    • McKillop I.H., Schmidt C.M., Cahill P.A., Sitzmann J.V. Inhibitory guanine nucleotide regulatory protein activation of mitogen activated protein kinase in hepatocellular carcinoma. Eur J Gastro Hep. 11:1999;761-768.
    • (1999) Eur J Gastro Hep , vol.11 , pp. 761-768
    • McKillop, I.H.1    Schmidt, C.M.2    Cahill, P.A.3    Sitzmann, J.V.4
  • 16
    • 0035313981 scopus 로고    scopus 로고
    • The MEK1-ERK map kinase pathway and the PI 3-kinase-Akt pathway independently mediate anti-apoptotic signals in HepG2 liver cancer cells
    • Mitsui H., Takuwa N., Maruyama T., et al. The MEK1-ERK map kinase pathway and the PI 3-kinase-Akt pathway independently mediate anti-apoptotic signals in HepG2 liver cancer cells. Int J Cancer. 92:2001;55-62.
    • (2001) Int J Cancer , vol.92 , pp. 55-62
    • Mitsui, H.1    Takuwa, N.2    Maruyama, T.3
  • 17
    • 0035196810 scopus 로고    scopus 로고
    • Hepatitis C virus core protein enhances the activation of the transcription factor, Elk1, in response to mitogenic stimuli
    • Fukudo K., Tsuchihara K., Hijikata M., et al. Hepatitis C virus core protein enhances the activation of the transcription factor, Elk1, in response to mitogenic stimuli. Hepatology. 33:2001;159-165.
    • (2001) Hepatology , vol.33 , pp. 159-165
    • Fukudo, K.1    Tsuchihara, K.2    Hijikata, M.3
  • 18
    • 0033755010 scopus 로고    scopus 로고
    • Hepatitis C virus core protein activates the MAPK/ERK cascade synergistically with the tumor promoter TPA, but not with epidermal growth factor or transforming growth factor α
    • Hayashi J., Aoki H., Kajino K. Hepatitis C virus core protein activates the MAPK/ERK cascade synergistically with the tumor promoter TPA, but not with epidermal growth factor or transforming growth factor α Hepatology. 32:2000;958-961.
    • (2000) Hepatology , vol.32 , pp. 958-961
    • Hayashi, J.1    Aoki, H.2    Kajino, K.3
  • 19
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • Alessi D.R., Cuenda A., Cohen P., et al. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem. 270:1995;27489-27494.
    • (1995) J Biol Chem , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3
  • 20
    • 14444279192 scopus 로고    scopus 로고
    • Identification of a novel inhibitor of mitogen-activated protein kinase kinase
    • Favata M.F., Horiuchi K.Y., Manos E.J., et al. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem. 273:1998;18623-18632.
    • (1998) J Biol Chem , vol.273 , pp. 18623-18632
    • Favata, M.F.1    Horiuchi, K.Y.2    Manos, E.J.3
  • 21
    • 17544373837 scopus 로고    scopus 로고
    • Survivin promotes cell proliferation in human hepatocellular carcinoma
    • Ito T., Shiraki K., Sugimoto K., et al. Survivin promotes cell proliferation in human hepatocellular carcinoma. Hepatology. 31:2000;1080-1085.
    • (2000) Hepatology , vol.31 , pp. 1080-1085
    • Ito, T.1    Shiraki, K.2    Sugimoto, K.3
  • 22
    • 0036176333 scopus 로고    scopus 로고
    • Expression of survivin messenger RNA correlates with poor prognosis in patients with hepatocellular carcinoma
    • Ikeguchi M., Ueda T., Sakatani T., et al. Expression of survivin messenger RNA correlates with poor prognosis in patients with hepatocellular carcinoma. Diagn Mol Pathol. 11:2002;33-40.
    • (2002) Diagn Mol Pathol , vol.11 , pp. 33-40
    • Ikeguchi, M.1    Ueda, T.2    Sakatani, T.3
  • 23
    • 0036725949 scopus 로고    scopus 로고
    • Bcl-xL overexpression in human hepatocellular carcinoma
    • Watanabe J., Kushihata F., Honda K., et al. Bcl-xL overexpression in human hepatocellular carcinoma. Int J Oncol. 21:2002;515-519.
    • (2002) Int J Oncol , vol.21 , pp. 515-519
    • Watanabe, J.1    Kushihata, F.2    Honda, K.3
  • 24
    • 0034950640 scopus 로고    scopus 로고
    • Expression and role of Bcl-xL in human hepatocellular carcinomas
    • Takehara T., Liu X., Fujimoto J., et al. Expression and role of Bcl-xL in human hepatocellular carcinomas. Hepatology. 34:2001;55-61.
    • (2001) Hepatology , vol.34 , pp. 55-61
    • Takehara, T.1    Liu, X.2    Fujimoto, J.3
  • 25
    • 0034743453 scopus 로고    scopus 로고
    • The integrin, alpha6beta1, is necessary for the matrix-dependent activation of FAK and MAP kinase and the migration of human hepatocarcinoma cells
    • Carloni V., Mazzocca A., Pantaleo P., et al. The integrin, alpha6beta1, is necessary for the matrix-dependent activation of FAK and MAP kinase and the migration of human hepatocarcinoma cells. Hepatology. 34:2001;42-49.
    • (2001) Hepatology , vol.34 , pp. 42-49
    • Carloni, V.1    Mazzocca, A.2    Pantaleo, P.3
  • 26
    • 0032984348 scopus 로고    scopus 로고
    • Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
    • Sebolt-Leopold J.S., Dudley D.T., Herrera R., et al. Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo. Nat Med. 5:1999;810-816.
    • (1999) Nat Med , vol.5 , pp. 810-816
    • Sebolt-Leopold, J.S.1    Dudley, D.T.2    Herrera, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.