Deep breathing in children with severe malaria: Indicator of metabolic acidosis and poor outcome

American Journal of Tropical Medicine and Hygiene

Volumn 55, Issue 5, 1996, Pages 521-524

  English, Michael ^a,b   Waruiru, Catherine ^b   Amukoye, Evans ^b   Murphy, Stephen ^a,b   Crawley, Jane ^a,b   Mwangi, Isaiah ^b   Peshu, Norbert ^b   Marsh, Kevin ^a,b  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMETHER; FANSIDAR; HEMOGLOBIN; QUININE;

ALKALOSIS; ANEMIA; ARTICLE; BLOOD SMEAR; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; HYPERPNEA; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALARIA; MALE; METABOLIC ACIDOSIS; MORBIDITY; MORTALITY; PH; PLASMODIUM FALCIPARUM; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY DISTRESS;

CINCHONA PUBESCENS; PLASMODIUM FALCIPARUM;

EID: 0029805470     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.1996.55.521     Document Type: Article

References (16)

1. World Bank, 1993. World Development Report. Oxford: Oxford University Press.
2. Marsh K, Forster D, Waruiru C, Mwangi I, Winstanley M, Marsh V, Newton C, Winstanley P, Warn P, Peshu N, Pasvol G, Snow R, 1995. Life threatening malaria in African children: clinical spectrum and simplified prognostic criteria. N Engl J Med 332: 1399-1404.
3. Molyneux M, Taylor T, Wirima J, Borgstein A, 1989. Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawian children. Q J Med 71: 441-459.
4. Warrell DA, Molyneux ME, Beales PF, 1990. Severe and complicated malaria. Trans R Soc Trop Med Hyg 84 (suppl 2): 1-65.
5. Lackritz EM, Campbell CC, Ruebush TK, Hightower AW, Wakube W, Steketee R, Were JB, 1992 Effect of blood transfusion on survival among children in a Kenyan hospital. Lancet 340: 524-528.
6. O'Dempsey TJD, McArdle TF, Laurence BE, Lamont JC, Todd JE, Greenwood BM, 1993. Overlap in the clinical features of pneumonia and malaria in African children. Trans R Soc Trop Med Hyg 87: 662-665.
7. Redd SC, Bloland PB, Kazembe PN, Patrick E, Tembenu R, Campbell CC, 1992. Usefulness of clinical case-definitions in guiding therapy for African children with malaria or pneumonia. Lancet 340: 1140-1143.
8. Dorward J, Knowles J, Dorward I, 1989. Treatment of severe anaemia in a rural hospital. Trop Doc 19: 155-158.
9. Hendrickse R, Barr D, Matthews T, 1991. Paediatrics in the Tropics. Oxford: Blackwell Scientific Publications.
10. Taylor T, Borgstein A, Molyneux M, 1993. Acid base status in paediatric Plasmodium falciparum malaria. Q J Med 86: 99-109.
11. Murphy S, English M, Waruiru C, Crawley J, Mwangi I, Amukoye E, Peshu N, Winstanley P, Marsh K, 1996. An open randomised comparison of artemether versus quinine in the treatment of cerebral malaria in African children. Trans R Soc Trop Med Hyg: (in press).
12. Snow R, Bastos de Azevedo I, Lowe B, Kabiru E, Nevill C, Mwankusye G, Marsh K, Teuscher T, 1994. Severe childhhod malaria in two areas of markedly different falciparum transmission in East Africa. Acta Trop 57: 289-300.
13. WHO, 1990. Acute Respiratory Infections in Children: Case Management in Small Hospitals in Developing Countries. Geneva: World Health Organization. WHO/ARI/90.5.
14. English M, Murphy S, Mwangi I, Crawley J, Peshu N, Marsh K, 1995. Interobserver variation in respiratory signs of severe malaria. Arch Dis Child 72: 334-336.
15. Behrmann R, Vaughan V, 1983. Nelson Textbook of Pediatrics. Philadelphia: W. B. Saunders Co.
16. English M, Waruiru C, Marsh K, 1996. Transfusion for respiratory distress in life-threatening childhood malaria. Am J Trop Med Hyg 55: 525-530.