Classification and Risk Stratification of Patients with Acute Chest Pain Using a Low Discriminatory Level of Cardiac Troponin T

Clinical Cardiology

Volumn 27, Issue 3, 2004, Pages 130-136

  Solymoss, B Charles ^a,b   Bourassa, Martial G ^a   Cernacek, Peter ^a   Fortier, Annik ^a   Théroux, Pierre ^b  

^a Department of Laboratory Medicine ^*  (Canada)

^b MONTREAL HEART INSTITUTE   (Canada)

Author keywords

Cardiac troponin T; Coronary disease; Death; Myocardial infarction

Indexed keywords

CREATINE KINASE MB; TROPONIN T;

ACUTE HEART INFARCTION; ADULT; AGED; ANALYTIC METHOD; ARTICLE; BLOOD SAMPLING; CHEMOLUMINESCENCE; CIGARETTE SMOKING; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DYSLIPIDEMIA; FEMALE; FOLLOW UP; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MORTALITY; PERCUTANEOUS CORONARY INTERVENTION; RISK ASSESSMENT; RISK FACTOR; THORAX PAIN;

EID: 1442329168     PISSN: 01609289     EISSN: None     Source Type: Journal    
DOI: 10.1002/clc.4960270306     Document Type: Article

References (24)

1. Hamm CW, Rawkilde J, Gerhardt W, Jorgensen P, Peheim E, Ljungdahl L, Goldman B, Katus HA: The prognostic value of serum troponin T in unstable angina. N Engl J Med 1992;327:146-150
2. Stubbs P, Collinson P, Moseley D, Greenwood T, Noble M: Prospective study of the role of cardiac troponin T in patients admitted with unstable angina. Br Med J 1996;313:262-264
3. Ohman ME, Armstrong PW, Christensen RH, Granger CB, Katus HA, Hamm CN, O'Hamesian MA, Wagner GS, Kleinman NS, Harrel FE, Califf RM, Popol EJ, for the GUSTO-IIa Investigators: Cardiac troponin T levels for risk stratification in acute myocardial ischemia. N Engl J Med 1996;335: 1333-1341
4. Solymoss BC, Bourassa MG, Wesolowska E, Théroux P, Dyrda I, Mondor L, Perrault D, Gilfix B: The role of cardiac troponin T and other new biochemical markers in evaluation and risk stratification of patients with acute chest pain syndromes. Clin Cardiol 1997;20:934-942
5. Collinson PO: Troponin T or troponin I or CK-MB (or none?). Eur Heart J 1998;19(suppl N):N16-24
6. Stubbs P: The cardiac troponins: Uses in routine clinical practice. Experiences from GUSTO and the clinical trials. Eur Heart J 1998;19(suppl N):N59-63
7. Ryan TJ, Antman EM, Brooks NH, Califf RM, Hillis LD, Hratzka LF, Rapaport E, Riegel B, Russel RO, Smith EE III, Weaver WD: ACC/AHA Practice Guidelines. 1999 Update: ACC/AHA Guidelines for the management of patients with acute myocardial infarction. J Am Coll Cardiol 1999; 34:890-911
8. Myocardial infarction redefined-A consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. The Joint European Society of Cardiology/American College of Cardiology Committee. J Am Coll Cardiol 2000;36:959-969
9. Braunwald E, Antman EM, Beasley JW, Califf RM, Cheitlin MD, Hochman JS, Jones RH, Kereiakes S, Kupersmith J, Levin TN, Pepine CJ, Schaeffer JW, Smith EE III, Steward DE, Théroux P: ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients with Unstable Angina). J Am Coll Cardiol 2000;36:970-1062
10. Bertrand ME, Simoons ML, Fox KAA, Wallentin LC, Hamm CW, McFadden E, De Feyter PJ, Specchia G, Ruzyllo W: Management of acute coronary syndromes: Acute coronary syndromes without persistent ST-segment elevation. Recommendation of the Task Force of the European Society of Cardiology. Eur Heart J 2000;21:1406-1432
11. Wu AHB, Apple FS, Gibler WB, Jesse RL, Warshaw MM, Valdes R: National Academy of Clinical Biochemistry standards of laboratory practice: Recommendations for the use of cardiac markers in coronary artery disease. Clin Chem 1999;45:1104-1121
12. Jaffe AS, Ravkilde J, Roberts R, Naslund U, Apple FS, Galvani M, Katus H: It's time for a change to troponin standard. Circulation 2000;102:1216-1220
13. Lindahl B, Venge P, Wallentin L: The FRISC experience with troponin T. Use as decision tool and comparison with other prognostic markers. Eur Heart J 1998;19(suppl N):51-58
14. The CAPTURE Investigators: Randomized placebo-controlled trial of abciximab before and during coronary intervention in refractory unstable angina. Lancet 1997;349:1429-1435
15. Hamm CW, Heeschen C, Goldmann B, Vahanian A, Adgey J, Miguel CM, Rutsch W, Berger J, Kootstra J, Simoons ML: Benefit of abciximab in patients with refractory unstable angina in relation to serum troponin T levels. c7E3 Fab Antiplatelet Therapy in Unstable Refractory Angina (CAPTURE) Study Investigators. N Engl J Med 1999;340:1623-1629
16. Heeschen C, Hamm CW, Goldmann B, Deu A, Langenbrink L, White D: Troponin concentration for stratification of patients with coronary syndromes in relation to therapeutic efficacy of tirofiban. Lancet 1999;354:1757-1762
17. Lindahl B, Venge P, Wallentin L for the FRISC study: Relation between troponin T and the risk of subsequent cardiac events in unstable coronary artery disease. Circulation 1966;93:1651-1657
18. Ottani F, Galvani M, Nicolini FA, Ferrini D, Pozzati A, Di Pasquale G, Jaffe AS: Elevated cardiac troponin levels predict the risk of adverse outcome in patients with acute coronary syndromes. Am Heart J 2000;140:917-927
19. Heidenreich PA, Allogiamento T, Melsop K, McDonald KM, Go AS, Hlatky MA: The prognostic value of troponin in patients with non-ST elevation acute coronary syndromes: A meta-analysis. J Am Coll Cardiol 2001; 38:478-485
20. Lindahl B, Venge P, Armstrong P, Barnathan E, Califf R, Simoons M, Topol E, Wallentin L: Troponin-T 0.03 μg/l is the most appropriate cut-off level between high and low risk acute coronary syndrome patients: Prospective verification in a large cohort of placebo patients from the GUSTO-IV ACS study. J Am Coll Cardiol 2001;37(suppl A):326A
21. Diderholm E, Andren B, Frostfeldt G, Genberg M, Jernberg T, Lagerqist B, Lindahl B, Venge P, Wallentin L, and the Fast Revascularization during InStability of Coronary artery disease (FRISC II) Investigators: The prognostic and therapeutic implications of increased troponin T levels and ST depression in unstable coronary artery disease: The FRISC II invasive troponin T electrocardiogram substudy. Am Heart J 2002;143:760-767
22. Lindahl B, Diderholm E, Lagerqist B, Venge P, Wallentin L, and the FRISC II Investigators: Mechanism behind the prognostic value of troponin T in unstable coronary artery disease: A FRISC II substudy. J Am Coll Cardiol 2001;38:979-986
23. Antman EM, Tanasijevic MJ, Thompson B, Schactman M, Mc-Cabe CH, Cannon CP, Gischer GA, Fung AY, Thompson C, Wybenga D, Braunwald E: Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes. N Engl J Med 1996;335:1342-1349
24. Stiegler H, Fisher Y, Vazquez-Jimenez JF, Graf J, Filzmaier K, Fausten B, Janssens U, Gressner AM, Kunz D: Lower cardiac troponin T and I results in heparin-plasma than in serum. Clin Chem 2000;46:1338-1344