Crystal structures of creatininase reveal the substrate binding site and provide an insight into the catalytic mechanism

Journal of Molecular Biology

Volumn 337, Issue 2, 2004, Pages 399-416

  Yoshimoto, Tadashi ^a   Tanaka, Nobutada ^b   Kanada, Naota ^a   Inoue, Takahiko ^a   Nakajima, Yoshitaka ^a   Haratake, Mamoru ^a   Nakamura, Kazuo T ^b   Xu, Yue ^a   Ito, Kiyoshi ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b SHOWA UNIVERSITY   (Japan)

Author keywords

Creatine; Creatininase; Creatinine; MAD, multiwavelength anomalous diffraction; PDB, protein data bank; SIRAS, single isomorphous replacement with anomalous scattering; X ray crystallography

Indexed keywords

AMIDASE; ASPARTIC ACID; CREATINE; CREATININASE; GLUTAMIC ACID; HISTIDINE; MANGANESE; ZINC;

ALPHA HELIX; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; CATALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; FOURIER ANALYSIS; GEOMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; PSEUDOMONAS PUTIDA; RING OPENING; X RAY CRYSTALLOGRAPHY;

PSEUDOMONAS; PSEUDOMONAS PUTIDA;

EID: 1442299234     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.01.022     Document Type: Article

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