Molecular targets for steroids in airway vascular smooth muscle

Archives of Physiology and Biochemistry

Volumn 111, Issue 4, 2003, Pages 341-344

  Horvath, Gabor ^a,b   Wanner, A ^b  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Bronchial circulation; Extraneuronal monoamine; Glucocorticoid; Nongenomic; Transporter; Vasoconstriction

Indexed keywords

2' FLUORO 3,4 DIHYDROXY 5 NITROBENZOPHENONE; CALCIUM ION; CATECHOL METHYLTRANSFERASE INHIBITOR; COMPLEMENTARY DNA; CORTICOSTERONE; CYCLOHEXIMIDE; DACTINOMYCIN; EXTRANEURONAL MONOAMINE TRANSPORTER; GLIBENCLAMIDE; GLUCOCORTICOID; GLUCOCORTICOID ANTAGONIST; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IBERIOTOXIN; ISOPRENALINE; MESSENGER RNA; MIFEPRISTONE; MONOAMINE; MONOAMINE OXIDASE INHIBITOR; NORADRENALIN; ORGANIC CATION TRANSPORTER; PARGYLINE; POTASSIUM CHANNEL; POTASSIUM ION; STEROID; UNCLASSIFIED DRUG;

AIRWAY; BINDING SITE; BRONCHIAL ARTERY; BRONCHUS; CELL MEMBRANE; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOCHEMISTRY; NORADRENALIN UPTAKE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR SMOOTH MUSCLE;

BINDING SITES; BRONCHI; BRONCHIAL ARTERIES; CELL MEMBRANE; CORTICOSTERONE; HUMANS; MUSCLE, SMOOTH, VASCULAR; NOREPINEPHRINE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; ORGANIC CATION TRANSPORT PROTEINS; POTASSIUM; POTASSIUM CHANNELS; RNA, MESSENGER; STEROIDS; SYMPORTERS;

EID: 14344254300     PISSN: 13813455     EISSN: None     Source Type: Journal    
DOI: 10.1080/13813450312331337559     Document Type: Conference Paper

References (9)

1. Brieva JL, Danta I, Wanner A (2000): Effect of an inhaled glucocorticosteroid on airway mucosal blood flow in mild asthma. Am J Resp Crit Care Med 161: 293-296.
2. Brieva J, Wanner A (2001); Adrenergic airway vascular smooth muscle responsiveness in healthy and asthmatic subjects. J Appl Physiol 90: 665-669.
3. Eisenhofer G (2001): The role of neuronal and extraneuronal plasma membrane transporters in the inactivation of peripheral catecholamines. Pharmacol Ther 91: 35-62.
4. Grundemann D, Schechinger B, Rappold GA, Schomig E (1998): Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter. Nat Neurosci 1: 349-351.
5. Horvath G, Lieb T, Conner GE, Salathe M, Wanner A (2000): Evaluation of extraneuronal norepinephrine uptake (uptake2) in isolated rabbit aortic smooth muscle cells using a single cell fluorescence method. Mol Biol Cell 415: 232A.
6. Horvath G, Lieb T, Conner GE, Salathe M, Wanner A (2001): Steroid sensitivity of norepinephrine uptake by human bronchial arterial and rabbit aortic smooth muscle cells. Am J Respir Cell Mol Biol 25: 500-506.
7. Horvath G, Torbati A, Conner GE, Salathe M, Wanner A (2002): Systemic ovalbumin sensitization downregulates norepinephrine uptake by rabbit aortic smooth muscle cells. Am J Respir Cell Mol Biol 27: 746-751.
8. Kumar SD, Brieva JL, Danta I, Wanner A (2000): Transient effect of inhaled fluticasone on airway mucosal blood flow in subjects with and without asthma. Am J Respir Crit Care Med 161: 918-921.
9. Trendelenburg U (1988): The extraneuronal uptake and metabolism of catecholamines. In Trendelenburg U, Weiner N, eds., Catecholamines I, handbook of experimental pharmacology 90/I, Berlin-Heidelberg-New York, Springer, pp 279-319.