Inhibition of transforming growth factor-β activation is a novel effect of chymase inactivation

Letters in Drug Design and Discovery

Volumn 2, Issue 1, 2005, Pages 19-22

  Takai, S ^a   Miyazaki, M ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Adhesion; Chymase; Fibrosis; Inhibitor; Transforming growth factor

Indexed keywords

4 [1 [[BIS(4 METHYLPHENYL)METHYL]CARBAMOYL] 3 (2 ETHOXYBENZYL) 4 OXO 2 AZETIDINYLOXY]BENZOIC ACID; BLEOMYCIN; CHYMASE; CHYMASE INHIBITOR; N [1 BENZYL 2,3 DIOXO 6 (2 PYRIDYLOXY)HEXYL] 2 (5 FORMYLAMINO 1,6 DIHYDRO 6 OXO 2 PHENYL 1 PYRIMIDINYL)ACETAMIDE; SUCCINYLVALYLPROLYLPHENYLALANYLPHOSPHONATE PHENYL ESTER; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; CARDIOMYOPATHY; CELL ADHESION; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; FIBROSIS; HUMAN; IN VITRO STUDY; LUNG FIBROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

EID: 14344250460     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/1570180053398433     Document Type: Article

References (57)

1. Urata, H.; Kinoshita, A.; Misono, K.S.; Bumpus, P.M.; Husain, A. J. Biol. Chem., 1990, 265, 22348-22357.
2. Takai, S.; Shiota, N.; Sakaguchi, M.; Muraguchi, H.; Matsumura, E.; Miyazaki, M. Clin. Chim. Acta, 1997, 205, 13-20.
3. Takai, S.; Shiota, N.; Kobayashi, S.; Matsumura, E.; Miyazaki, M. FEBS Lett., 1997, 412, 86-90.
4. Caughey, G.H.; Raymond, W.W.; Wolters, P.J. Biochim. Biophys. Acta, 2000, 1480, 245-257.
5. Takai, S.; Shiota, N.; Yamamoto, D.; Okunishi, H.; Miyazaki, M. Life Sci., 1996, 55, 591-597.
6. Powell, J.S.; Clozel, J.P.; Muler, R.K.M.; Kuhn, H.; Hefti, F.; Hosang, M.; Baumgartner, H.R. Science, 1991, 245, 186-188.
7. Kauffman, R.F.; Bean, J.S.; Zimmerman, K.M.; Brown, R.F.; Steinberg, M.I. Life Sci., 1991, 49, PL223-PL228.
8. MERCATOR Study Group. Circulation, 1992, 86, 100-110.
9. Peters, S.; Getting, B.; Trummel, M.; Rust, H.; Brattstrom, A. J. Invasive. Cardiol., 2001, 13, 93-97.
10. Takai, S.; Sakaguchi, M.; Jin, D.; Yamada, M.; Kirimura, K..; Miyazaki, M. Clin. Chim. Acta, 2001, 305, 191-195.
11. Takai, S.; Miyazaki, M. Jpn. J. Pharmacol., 2002, 90, 223-227.
12. Miyazaki, M.; Shiota, N.; Sakonjo, H.; Takai, S. Jpn. J. Pharmacol., 1999, 79, 455-460.
13. Miyazaki, M.; Wada, T.; Shiota, N.; Takai, S. J. Hum. Hypertens., 1999, 13 (Suppl. 1), S21-S25.
14. Takai, S.; Sakonjo, H.; Fukuda, K.; Jin, D.; Sakaguchi, M.; Kamoshita, K.; Ishida, K.; Sukenaga, Y.; Miyazaki, M. J. Pharmacol. Exp. Ther., 2003, 304, 841-844.
15. Taipale, J.; Lohi, J.; Saarinen, J.; Kovanen, P.T.; Keski-Oja, J. J. Biol. Chem., 1995, 270, 4689-4896.
16. Takai, S.; Jin, D.; Sakaguchi, M.; Katayama, S.; Muramatsu, M.; Sakaguchi, M.; Matsumura, E.; Kim, S.; Miyazaki, M. J. Pharmacol. Exp. Ther., 2003, 305, 17-23.
17. Kanzaki, T.; Olofsson, A.; Moren, A.; Wernstedt, C.; Hellman, U.; Miyazono, K.; Claesson-Welsh, L.; Heldin, C.H. Cell, 1990, 61, 1051-1061.
18. Lawrence, D.A.; Pircher, R.; Jullien, P. Biochem. Biophys. Res. Commun., 1985, 133, 1026-1034.
19. Lyons, R.M.; Gentry, L.E.; Purchio, A.F.; Moses, H.L. J. Cell. Biol. 1990, 110, 1361-1367.
20. Miyazono, K.; Heldin, C.H. Nature, 1989, 338, 158-160.
21. Persinger, M.A.; Lepage, P.; Simard, J.P.; Parker, G.H. Br. J. Dermatol., 1983, 108, 179-187.
22. Liebman, S.M.; Langer, J.C.; Marshall, J.S.; Collins, S.M. Am. J. Surg., 1993, 165, 127-130.
23. Langer, J.C.; Liebman, S.M.; Monk, P.K.; Pelletier, G.J. Mast cell mediators and peritoneal adhesion formation in the rat. J. Surg. Res., 1995, 59, 344-348.
24. Adachi, S.; Maruyama, T.; Kondo, T.; Todoroki, T.; Fukao, K. Surg. Today, 1999, 29, 51-54.
25. Yao, Y.L.; Ishihara, T.; Takai, S.; Miyazaki, M.; Mita, S. J. Surg. Res., 2000, 92, 40-44.
26. Metcalfe, D.D. Allergy, 1984, 53, 563-575.
27. Ramos, B.F.; Zhang, Y.; Jakschik, B.A.; Qureshi, R. J. Immunol., 1991, 147, 1636-1641.
28. Das, A.M.; Flower, R.J.; Perretti, M. J. Immunol., 1997, 159, 1466-1473.
29. Chegini, N. Eur. J. Surg. (Suppl), 1997, 577, 17-23.
30. Williams, R.S.; Rossi, A.M.; Chegini, N.; Schultz, G. J. Surg. Res., 1992, 52, 65-70.
31. Chegini, N.; Gold, L.I.; Williams, R.S.; Masterson, B. J. Obstet. Gynecol. 1994, 83, 449-454.
32. Lucas, P.A.; Warejcka, D.J.; Young, H.E.; Lee, B.Y. J. Surg. Res., 1996, 65, 135-138.
33. Crowe, M.J.; Doetschman, T.; Greenhalgh, D.G. J. Invest. Dermatol. 2000, 115, 3-11.
34. Okamoto, Y.; Takai, S.; Yamada, M.; Miyazaki, M. Fertil. Steril., 2002, 77, 1044-1048.
35. Soga, Y.; Takai, S.; Koyama, T.; Okamoto, Y.; Ikeda, T.; Nishimura, K.; Miyazaki, M.; Komeda, M. J. Thorac. Cardiovasc. Surg., 2004, 127, 72-78.
36. Maruichi, M.; Takai, S.; Sugiyama, T.; Ueki, M.; Oku, H.; Sakaguchi, M.; Okamoto, Y.; Muramatsu, M.; Ikeda, T.; Miyazaki, M. Exp. Eye Res., 2004, 79, 111-118.
37. Okamoto, Y.; Takai, S.; Miyazaki, M. Jpn. J. Pharmacol., 2002, 90, 94-96.
38. Okamoto, Y.; Takai, S.; Miyazaki, M. J. Surg. Res., 2002, 107, 219-22.
39. Eghbali, M.; Tomek, R.; Woods, C.; Bhambi, B. Proc. Natl. Acad. Sci. U. S. A., 1991, 55, 795-799.
40. Li.; R.K.; Li, G.; Mickle, D.A.; Weisel; R.D.; Merante, F.; Luss, H.; Rao, V.; Christakis, G.T.; Williams, W.G. Circulation, 1997, 96, 874-881.
41. Panizo, A.; Mindan, F.J.; Galindo, M.F.; Cenarruzabeitia, E.; Hernandez, M.; Diez, J. J. Hypertens., 1995, 13, 1201-1208.
42. Patella, V.; Marino, I.; Arbustini, E.; Lamparter-Schummert, B.; Verga, L.; Adt, M.; Marone, G. Circulation, 1998, 97, 971-978.
43. Dixon, I.M.; Ju, H.; Reid, N.L.; Scammell-La Fleur, T.; Werner, J.P.; Jasmin, G. J. Mol. Cell. Cardiol., 1997, 29, 1837-1850.
44. Lijnen, P.J.; Petrov, V.V.; Fagard, R.H. J. Renin Angiotensin Aldosterone Syst., 2001, 2, 117-122.
45. Kuwahara, F.; Kai, H.; Tokuda, K.; Kai, M.; Takeshita, A.; Egashira, K.; Imaizumi, T. Circulation, 2002, 106, 130-135.
46. Takai, S.; Jin, D.; Sakaguchi, M.; Katayama, S.; Muramatsu, M.; Sakaguchi, M.; Matsumura, E.; Kim, S.; Miyazaki, M. J. Pharmacol. Exp. Ther., 2003, 305, 17-23.
47. Nakamura, F.; Nagano, M.; Kobayashi, R.; Higaki, J.; Mikami, H.; Kawaguchi, N.; Onishi, S.; Ogihara, T. Am. J. Physiol., 1994, 267, H2297-H2304.
48. Taniyama, Y.; Morishita, R.; Hiraoka, K.; Aoki, M.; Nakagami, H.; Yamasaki, K.; Matsumoto, K.; Nakamura, T.; Kaneda, Y.; Ogihara, T. Circulation, 2000, 102, 246-252.
49. Broekelmann, T.J.; Limper, A.H.; Colby, T.V.; McDonald, J.A. Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc. Natl. Acad. Sci. U. S. A., 1991, 88, 6642-6646.
50. Zhang, H.Y.; Gharaee-Kermani, M.; Zhang, K.; Karmiol, S.; Phan, S.H. Lung fibroblast alpha-smooth muscle actin expression and contractile phenotype in bleomycin-induced pulmonary fibrosis. Am. J. Pathol., 1996, 148, 527-537.
51. Giri, S.N.; Hyde, D.M.; Hollinger, M.A. Thorax, 1993, 48, 959-966.
52. Nakao, A.; Fujii, M.; Matsumura, R.; Kumano, K.; Saito, Y.; Miyazono, K.; Iwamoto, I. J. Clin. Invest., 1999, 104, 5-11.
53. Goto, T.; Befus, D.; Low, R.; Bienenstock, J. Mast cell heterogeneity and hyperplasia in bleomycin-induced pulmonary fibrosis of rats. Am. Rev. Respir. Dis., 1984, 130, 797-802.
54. Mori, H.; Kawada, K.; Zhang, P.; Uesugi, Y.; Sakamoto, O.; Koda, A. Bleomycin-induced pulmonary fibrosis in genetically mast cell-deficient WBB6F1-W/Wv mice and mechanism of the suppressive effect of tranilast, an antiallergic drug inhibiting mediator release from mast cells, on fibrosis. Int. Arch. Allergy Appl. Immunol., 1991, 95, 195-201.
55. Tomioka, M.; Goto, T.; Lee, T.D.; Bienenstock, J.; Befus, A.D. Isolation and characterization of lung mast cells from rats with bleomycin-induced pulmonary fibresis. Immunology, 1989, 66, 439-44.
56. Sukenaga, Y.; Kamoshita, K.; Takai, S.; Miyazaki, M. Jpn. J. Pharmacol., 2002, 90, 218-222.
57. Sakaguchi, M.; Takai, S.; Jin, D.; Okamoto, Y.; Muramatsu, M.; Kim, S.; Miyazaki, M. A specific chymase inhibitor, NK3201, suppresses bleomycin-induced pulmonary fibrosis in hamsters. Eur. J. Pharmacol. 2004, 493, 173-176.