Neurocognitive outcomes: The year in review

Current Opinion in Anaesthesiology

Volumn 18, Issue 1, 2005, Pages 57-62

  Murkin, John M ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Anemia; Brain; Cardiac surgery; CNS; Cognitive testing; Emboli; Filter; TCD; Transcranial Doppler

Indexed keywords

ANEMIA; BRAIN BLOOD FLOW; BRAIN EMBOLISM; CARDIOPULMONARY BYPASS; COGNITIVE DEFECT; DOPPLER ECHOGRAPHY; GAS EMBOLISM; HUMAN; HYPERGLYCEMIA; HYPERTHERMIA; HYPOTHERMIA; HYPOXEMIA; HYPOXIA; NEUROPSYCHOLOGICAL TEST; OFF PUMP SURGERY; PERIOPERATIVE PERIOD; PRIORITY JOURNAL; REVIEW;

EID: 14144253553     PISSN: 09527907     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001503-200502000-00010     Document Type: Review

References (19)

1. Lund C, Hol PK, Lundblad R, et al. Comparison of cerebral embolization during off-pump and on-pump coronary artery bypass surgery. Ann Thorac Surg 2003; 76:765-770.
2. Abu-Omar Y, Balacumaraswami L, Pigott DW, et al. Solid and gaseous cerebral microembolization during off-pump, on-pump, and open cardiac surgery procedures. J Thorac Cardiovasc Surg 2004; 127:1759-1765. One of the first clinical studies claiming to discriminate particulate from gaseous cerebral emboli. Interesting, but further corroboration is required.
3. Schmitz C, Weinreich S, White J, et al. Can particulate extraction from the ascending aorta reduce neurologic injury in cardiac surgery? J Thorac Cardiovasc Surg 2003; 126:1829-1838. An important study demonstrating significant CNS benefit from intra-aortic particulate capture.
4. Merkle F, Boettcher W, Schulz F, et al. Reduction of microemboli count in the priming fluid of cardiopulmonary bypass circuits. J Extra Corpor Technol 2003; 35:133-138.
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7. Mathew JP, Shernan SK, White WD, et al. Preliminary report of the effects of complement suppression with pexelizumab on neurocognitive decline after coronary artery bypass graft surgery. Stroke 2004; [Epub ahead of print].
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9. Ho PM, Arciniegas DB, Grigsby J, et al. Predictors of cognitive decline following coronary artery bypass graft surgery. Ann Thorac Surg 2004; 77:597-603.
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11. van Dijk D, Moons KG, Keizer AM, et al. Octopus Study Group. Association between early and three month cognitive outcome after off-pump and on-pump coronary bypass surgery. Heart 2004; 90:431-434. Further results looking at early and mid-term outcomes from one of the largest, randomized comparisons of beating heart versus conventional CABG to date.
12. Rankin KP, Kochamba GS, Boone KB, et al. Presurgical cognitive deficits in patients receiving coronary artery bypass graft surgery. J Int Neuropsychol Soc 2003; 9:913-924.
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14. Zimpfer D, Czerny M, Vogt F, et al. Neurocognitive deficit following coronary artery bypass grafting: a prospective study of surgical patients and nonsurgical controls. Ann Thorac Surg 2004; 78:513-518. An important, well-conducted and useful study employing a non-surgical control group and identifying an independent and persistent CNS risk associated with cardiac surgery.
15. Silbert BS, Maruff P, Evered LA, et al. Detection of cognitive decline after coronary surgery: a comparison of computerized and conventional tests. Br J Anaesth 2004; 92:814-820.
16. Kadoi Y, Saito S, Takahashi K, et al. Jugular venous oxygen saturation during mild hypothermic versus normothermic cardiopulmonary bypass in elderly patients. Japan Surg Today 2004; 34:399-404.
17. Jonas RA, Wypij D, Roth SJ, et al. The influence of hemodilution on outcome after hypothermic cardiopulmonary bypass: results of a randomized trial in infants. J Thorac Cardiovasc Surg 2003; 126:1765-1774. A very important, clinical outcome study in infants demonstrating long-term developmental delay associated with more-profound degrees of intraoperative anemia.
18. Floyd TF, McGarvey M, Ochroch EA, et al. Perioperative changes in cerebral blood flow after cardiac surgery: influence of anemia and aging. Ann Thorac Surg 2003; 76:2037-2042.
19. Browne SM, Halligan PW, Wade DT, Taggart DP. Postoperative hypoxia is a contributory factor to cognitive impairment after cardiac surgery. J Thorac Cardiovasc Surg 2003; 126:1061-1064. A relatively novel line of investigation identifying postoperative hypoxemia as another contributory factor in cognitive dysfunction.