Osteoblast-specific expression of insulin-like growth factor-1 in bone of transgenic mice induces insulin-like growth factor binding protein-5

Bone

Volumn 36, Issue 2, 2005, Pages 224-231

  Rutter, Meilan M ^a   Markoff, Edith ^a   Clayton, Lisa ^a   Akeno, Nagako ^b   Zhao, Guisheng ^b   Clemens, Thomas L ^c   Chernausek, Steven D ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c University of Alabama at Birmingham   (United States)

Author keywords

Bone formation; Insulin like growth factor (IGF I); Insulin like growth factor binding protein (IGFBP); Paracrine regulation; Transgenic mice

Indexed keywords

IODINE 125; LIGAND; MESSENGER RNA; SOMATOMEDIN BINDING PROTEIN 4; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN C;

AGE DISTRIBUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CELL SPECIFICITY; CONTROLLED STUDY; HORMONAL REGULATION; IMMUNOBLOTTING; IN VIVO STUDY; ISOTOPE LABELING; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; PARACRINE SIGNALING; POSTNATAL DEVELOPMENT; PROTEIN CONTENT; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN INDUCTION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL SIGNIFICANCE; TISSUE DISTRIBUTION; TRANSGENIC MOUSE;

EID: 14144249534     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2004.10.005     Document Type: Article

References (51)

1. J. Baker, J.P. Liu, E.J. Robertson, and A. Efstratiadis Role of insulin-like growth factors in embryonic and postnatal growth Cell 75 1993 73 82
2. M. Zhang, S. Xuan, M.L. Bouxsein, D. von Stechow, N. Akeno, and M.C. Faugere Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization J. Biol. Chem. 277 2002 44005 44012
3. S. Mohan, C. Richman, R. Guo, Y. Amaar, L.R. Donahue, and J. Wergedal Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms Endocrinology 144 2003 929 936
4. S. Mohan, and D.J. Baylink IGF system components and their role in bone metabolism R.G. Rosenfeld C.T. Roberts Jr. The IGF system: molecular biology, physiology, and clinical applications 1999 Humana Press Totowa (NJ) 457 496
5. C.A. Conover In vitro studies of insulin-like growth factor I and bone Growth Horm. IGF Res. 10 Suppl. B 2000 S107 S110
6. P.A. Hill, A. Tumber, and M.C. Meikle Multiple extracellular signals promote osteoblast survival and apoptosis Endocrinology 138 1997 3849 3858
7. A. Tumber, M.C. Meikle, and P.A. Hill Autocrine signals promote osteoblast survival in culture J. Endocrinol. 167 2000 383 390
8. T.L. McCarthy, M. Centrella, and E. Canalis Regulatory effects of insulin-like growth factors I and II on bone collagen synthesis in rat calvarial cultures Endocrinology 124 1989 301 309
9. E. Canalis, S. Rydziel, A.M. Delany, S. Varghese, and J.J. Jeffrey Insulin-like growth factors inhibit interstitial collagenase synthesis in bone cell cultures Endocrinology 136 1995 1348 1354
10. P.A. Hill, J.J. Reynolds, and M.C. Meikle Osteoblasts mediate insulin-like growth factor-I and -II stimulation of osteoclast formation and function Endocrinology 136 1995 124 131
11. J.I. Jones, and D.R. Clemmons Insulin-like growth factors and their binding proteins: biological actions Endocr. Rev. 16 1995 3 34
12. S.M. Firth, and R.C. Baxter Cellular actions of the insulin-like growth factor binding proteins Endocr. Rev. 23 2002 824 854
13. S. Mohan, and D.J. Baylink Insulin-like growth factor system components and the coupling of bone formation to resorption Horm. Res. 45 Suppl. 1 1996 59 62
14. S. Mohan, C.M. Bautista, J. Wergedal, and D.J. Baylink Isolation of an inhibitory insulin-like growth factor (IGF) binding protein from bone cell-conditioned medium: a potential local regulator of IGF action Proc. Natl. Acad. Sci. U. S. A. 86 1989 8338 8342
15. C.M. Bautista, D.J. Baylink, and S. Mohan Isolation of a novel insulin-like growth factor (IGF) binding protein from human bone: a potential candidate for fixing IGF-II in human bone Biochem. Biophys. Res. Commun. 176 1991 756 763
16. P.G. Campbell, and D.L. Andress Insulin-like growth factor (IGF)-binding protein-5-(201-218) region regulates hydroxyapatite and IGF-I binding Am. J. Physiol. 273 1997 E1005 E1013
17. V. Nicolas, S. Mohan, Y. Honda, A. Prewett, R.D. Finkelman, and D.J. Baylink An age-related decrease in the concentration of insulin-like growth factor binding protein-5 in human cortical bone Calcif. Tissue Int. 57 1995 206 212
18. C. Richman, D.J. Baylink, K. Lang, C. Dony, and S. Mohan Recombinant human insulin-like growth factor-binding protein-5 stimulates bone formation parameters in vitro and in vivo Endocrinology 140 1999 4699 4705
19. S. Mohan, Y. Nakao, Y. Honda, E. Landale, U. Leser, and C. Dony Studies on the mechanisms by which insulin-like growth factor (IGF) binding protein-4 (IGFBP-4) and IGFBP-5 modulate IGF actions in bone cells J. Biol. Chem. 270 1995 20424 20431
20. F. Bauss, K. Lang, C. Dony, and L. Kling The complex of recombinant human insulin-like growth factor-I (rhIGF-I) and its binding protein-5 (IGFBP-5) induces local bone formation in murine calvariae and in rat cortical bone after local or systemic administration Growth Horm. IGF Res. 11 2001 1 9
21. D.L. Andress IGF-binding protein-5 stimulates osteoblast activity and bone accretion in ovariectomized mice Am. J. Physiol. Endocrinol. Metab. 281 2001 E283 E288
22. D.L. Andress, and R.S. Birnbaum Human osteoblast-derived insulin-like growth factor (IGF) binding protein-5 stimulates osteoblast mitogenesis and potentiates IGF action J. Biol. Chem. 267 1992 22467 22472
23. C.A. Conover, and M.C. Kiefer Regulation and biological effect of endogenous insulin-like growth factor binding protein-5 in human osteoblastic cells J. Clin. Endocrinol. Metab. 76 1993 1153 1159
24. Y. Imai, W.H. Busby Jr., C.E. Smith, J.B. Clarke, A.J. Garmong, and G.D. Horwitz Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture J. Clin. Invest. 100 1997 2596 2605
25. R.D. Devlin, Z. Du, V. Buccilli, V. Jorgetti, and E. Canalis Transgenic mice overexpressing insulin-like growth factor binding protein-5 display transiently decreased osteoblastic function and osteopenia Endocrinology 143 2002 3955 3962
26. S. Amarnani, H.L. Merriman, T.A. Linkhart, D.J. Baylink, and S. Mohan Autocrine regulators of MC3T3-E1 cell proliferation J. Bone Miner. Res. 8 1993 157 165
27. M. Zhang, M.C. Faugere, H. Malluche, C.J. Rosen, S.D. Chernausek, and T.L. Clemens Paracrine overexpression of IGFBP-4 in osteoblasts of transgenic mice decreases bone turnover and causes global growth retardation J. Bone Miner. Res. 18 2003 836 843
28. G. Zhao, M.C. Monier-Faugere, M.C. Langub, Z. Geng, T. Nakayama, and J.W. Pike Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation Endocrinology 141 2000 2674 2682
29. P.K. Smith, R.I. Krohn, G.T. Hermanson, A.K. Mallia, F.H. Gartner, and M.D. Provenzano Measurement of protein using bicinchoninic acid Anal. Biochem. 150 1985 76 85
30. P. Hossenlopp, D. Seurin, B. Segovia-Quinson, S. Hardouin, and M. Binoux Analysis of serum insulin-like growth factor binding proteins using Western blotting: use of the method for titration of the binding proteins and competitive binding studies Anal. Biochem. 154 1986 138 143
31. D.A. Salih, G. Tripathi, C. Holding, T.A. Szestak, M.I. Gonzalez, and E.J. Carter Insulin-like growth factor-binding protein 5 (Igfbp5) compromises survival, growth, muscle development, and fertility in mice Proc. Natl. Acad. Sci. U. S. A. 101 2004 4314 4319
32. Muller PY, Janovjak H, Miserez AR, Dobbie Z. Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques 2002;32:1372-4, 1376, 1378-9.
33. J.I. Jones, A. Gockerman, W.H. Busby Jr., C. Camacho-Hubner, and D.R. Clemmons Extracellular matrix contains insulin-like growth factor binding protein-5: potentiation of the effects of IGF-I J. Cell Biol. 121 1993 679 687
34. Y. Dong, and E. Canalis Insulin-like growth factor (IGF) I and retinoic acid induce the synthesis of IGF-binding protein 5 in rat osteoblastic cells Endocrinology 136 1995 2000 2006
35. Y. Hakeda, H. Kawaguchi, M. Hurley, C.C. Pilbeam, C. Abreu, and T.A. Linkhart Intact insulin-like growth factor binding protein-5 (IGFBP-5) associates with bone matrix and the soluble fragments of IGFBP-5 accumulated in culture medium of neonatal mouse calvariae by parathyroid hormone and prostaglandin E2-treatment J. Cell Physiol. 166 1996 370 379
36. T. Ueland, J. Bollerslev, T.B. Hansen, E.N. Ebbesen, L. Mosekilde, and K. Brixen Increased cortical bone content of insulin-like growth factors in acromegalic patients J. Clin. Endocrinol. Metab. 84 1999 123 127
37. A.J. D'Ercole, and L.E. Underwood Ontogeny of somatomedin during development in the mouse. Serum concentrations, molecular forms, binding proteins, and tissue receptors Dev. Biol. 79 1980 33 45
38. B. Gabbitas, and E. Canalis Insulin-like growth factors sustain insulin-like growth factor-binding protein-5 expression in osteoblasts Am. J. Physiol. 275 1998 E222 E228
39. T.L. McCarthy, S. Casinghino, M. Centrella, and E. Canalis Complex pattern of insulin-like growth factor binding protein expression in primary rat osteoblast enriched cultures: regulation by prostaglandin E2, growth hormone, and the insulin-like growth factors J. Cell. Physiol. 160 1994 163 175
40. P. Ye, and J. D'Ercole Insulin-like growth factor I (IGF-I) regulates IGF binding protein-5 gene expression in the brain Endocrinology 139 1998 65 71
41. K.M. Thrailkill, S.R. Siddhanti, J.L. Fowlkes, and L.D. Quarles Differentiation of MC3T3-E1 osteoblasts is associated with temporal changes in the expression of IGF-I and IGFBPs Bone 17 1995 307 313
42. K.M. Thrailkill, L.D. Quarles, H. Nagase, K. Suzuki, D.M. Serra, and J.L. Fowlkes Characterization of insulin-like growth factor-binding protein 5-degrading proteases produced throughout murine osteoblast differentiation Endocrinology 136 1995 3527 3533
43. C.A. Conover, L.K. Bale, J.T. Clarkson, and O. Torring Regulation of insulin-like growth factor binding protein-5 messenger ribonucleic acid expression and protein availability in rat osteoblast-like cells Endocrinology 132 1993 2525 2530
44. S. Kanzaki, S. Hilliker, D.J. Baylink, and S. Mohan Evidence that human bone cells in culture produce insulin-like growth factor-binding protein-4 and -5 proteases Endocrinology 134 1994 383 392
45. C. Camacho-Hubner, W.H. Busby Jr., R.H. McCusker, G. Wright, and D.R. Clemmons Identification of the forms of insulin-like growth factor-binding proteins produced by human fibroblasts and the mechanisms that regulate their secretion J. Biol. Chem. 267 1992 11949 11956
46. M.R. Schneider, E. Wolf, A. Hoeflich, and H. Lahm IGF-binding protein-5: flexible player in the IGF system and effector on its own J. Endocrinol. 172 2002 423 440
47. C. Hassager, L.A. Fitzpatrick, E.M. Spencer, B.L. Riggs, and C.A. Conover Basal and regulated secretion of insulin-like growth factor binding proteins in osteoblast-like cells is cell line specific J. Clin. Endocrinol. Metab. 75 1992 228 233
48. S.K. Durham, M.C. Kiefer, B.L. Riggs, and C.A. Conover Regulation of insulin-like growth factor binding protein 4 by a specific insulin-like growth factor binding protein 4 proteinase in normal human osteoblast-like cells: implications in bone cell physiology J. Bone Miner. Res. 9 1994 111 117
49. J.B. Lawrence, C. Oxvig, M.T. Overgaard, L. Sottrup-Jensen, G.J. Gleich, and L.G. Hays The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A Proc. Natl. Acad. Sci. U. S. A. 96 1999 3149 3153
50. X. Qin, D. Byun, K.H. Lau, D.J. Baylink, and S. Mohan Evidence that the interaction between insulin-like growth factor (IGF)-II and IGF binding protein (IGFBP)-4 is essential for the action of the IGF-II-dependent IGFBP-4 protease Arch. Biochem. Biophys. 379 2000 209 216
51. N. Miyakoshi, C. Richman, Y. Kasukawa, T.A. Linkhart, D.J. Baylink, and S. Mohan Evidence that IGF-binding protein-5 functions as a growth factor J. Clin. Invest. 107 2001 73 81