Correlation of three-dimensional structures with the antibacterial activity of a group of peptides designed based on a nontoxic bacterial membrane anchor

Journal of Biological Chemistry

Volumn 280, Issue 7, 2005, Pages 5803-5811

  Wang, Guangshun ^a   Li, Yifeng ^a   Li, Xia ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CORRELATION METHODS; ESCHERICHIA COLI; HYDROPHOBICITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYPEPTIDES;

ANTIBACTERIAL PEPTIDES; ANTIMICROBIAL PEPTIDES; MEMBRANE ANCHORS; NONTOXIC MEMBRANES;

BACTERIA;

BACTERIAL ENZYME; DIOCTANOYL PHOSPHATIDYLGLYCEROL; ESCHERICHIA COLI PROTEIN; GLYCEROL DERIVATIVE; GLYCYLLEUCYLPHENYLALANYLASPARTYLISOLEUCYLISOLEUCYLLYSYLLYSYLISOLEUCYL ALANYLGLUTAMYLSERYLPHENYLALANINE; GLYCYLLEUCYLPHENYLALANYLASPARTYLISOLEUCYLVALYLLYSYLLYSYLLEUCYLVALYLSERYL ASPARTYLPHENYLALANINE; GLYCYLLEUCYLPHENYLALANYLASPARTYLISOLEUCYLVALYLLYSYLSERYLLEUCYLVALYLSERYL ASPARTYLPHENYLALANINE; GLYCYLLEUCYLPHENYLALANYLASPARTYLLYSYLLEUCYLLYSYLSERYLLEUCYLVALYLSERYL ASPARTYLASPARTYLLYSYLLYSINE; GLYCYLLEUCYLPHENYLALANYLASPARTYLLYSYLLEUCYLLYSYLSERYLLEUCYLVALYLSERYL ASPARTYLPHENYLALANINE; LIPID; POLYPEPTIDE; UNCLASSIFIED DRUG; WATER;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL MEMBRANE; CARBON NUCLEAR MAGNETIC RESONANCE; CIRCULAR DICHROISM; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG DESIGN; ELECTRICITY; ENERGY TRANSFER; ESCHERICHIA COLI; HYDROPHOBICITY; LIPID BILAYER; LIPID VESICLE; MEMBRANE POTENTIAL; MICELLE; MOLECULE; NITROGEN NUCLEAR MAGNETIC RESONANCE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; SEQUENCE ANALYSIS; SOLID STATE; SPECTROSCOPY; STRUCTURE ANALYSIS; SURFACE PROPERTY;

ANTI-BACTERIAL AGENTS; CELL MEMBRANE; CIRCULAR DICHROISM; DRUG DESIGN; ESCHERICHIA COLI; HYDROPHOBICITY; LIPID BILAYERS; LIPIDS; MAGNETIC RESONANCE SPECTROSCOPY; MICELLES; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; PEPTIDES; PHOSPHATIDYLGLYCEROLS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SODIUM DODECYL SULFATE; STRUCTURE-ACTIVITY RELATIONSHIP; WATER;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 14044268292     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M410116200     Document Type: Article

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