Interaction between the T4 helicase-loading protein (gp59) and the DNA polymerase (gp43): A locking mechanism to delay replication during replisome assembly

Biochemistry

Volumn 44, Issue 7, 2005, Pages 2305-2318

  Xi, Jun ^a   Zhuang, Zhihao ^a   Zhang, Zhiquan ^b   Selzer, Tzvia ^a   Spiering, Michelle M ^a   Hammes, Gordon G ^b   Benkovic, Stephen J ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; COMPLEXATION; CROSSLINKING; CRYSTAL STRUCTURE; DESORPTION; DNA; FLUORESCENCE; IONIZATION; LASER BEAMS; POLYMERIZATION; POLYMERS; PROTEINS; SYNTHESIS (CHEMICAL);

DNA REPLICATION; FLUORESCENCE MICROSCOPY; HOLOENZYMES; TRYPTIC DIGESTION;

ENZYME KINETICS;

CYSTEINE; DNA POLYMERASE; EXONUCLEASE; GLYCOPROTEIN; GLYCOPROTEIN GP 43; GLYCOPROTEIN GP 59; HOLOENZYME; REPLISOME; UNCLASSIFIED DRUG;

ARTICLE; CROSS LINKING; DNA REPLICATION; DNA SYNTHESIS; ENZYME ACTIVITY; FLUORESCENCE MICROSCOPY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR INTERACTION; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION;

BACTERIOPHAGE T4; CROSS-LINKING REAGENTS; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA HELICASES; DNA PRIMERS; DNA REPLICATION; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; EXONUCLEASES; FLUORESCENCE RESONANCE ENERGY TRANSFER; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HETERODUPLEXES; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN PROCESSING, POST-TRANSLATIONAL; REPLICON; SUBSTRATE SPECIFICITY; TEMPLATES, GENETIC; VIRAL PROTEINS;

EID: 14044254854     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0479508     Document Type: Article

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