Acute insulin responses to intravenous glucose and CLP-1 are independent of preceding high-freguency insulin pulse-defects induced by glucose entrainment in healthy humans

Hormone and Metabolic Research

Volumn 37, Issue 1, 2005, Pages 40-44

  Juhl, C B ^a,b   Sturis, J ^c   Hollingdal, M ^a   Schmitz, O ^a,b  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c NOVO NORDISK A S   (Denmark)

Author keywords

Entrainment; Human; Insulin secretion; Pulsatility

Indexed keywords

GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INSULIN;

ADULT; ARTICLE; BLOOD SAMPLING; CELL FUNCTION; CONCENTRATION RESPONSE; FEMALE; HIGH FREQUENCY OSCILLATION; HUMAN; INSULIN RELEASE; INSULIN RESPONSE; MALE; NORMAL HUMAN; OSCILLATION; PRIORITY JOURNAL; PULSE RATE; STIMULUS;

ADAPTATION, PHYSIOLOGICAL; ADULT; BLOOD GLUCOSE; FEMALE; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE; HUMANS; INFUSIONS, INTRAVENOUS; INSULIN; MALE; PEPTIDE FRAGMENTS; PERIODICITY; PROTEIN PRECURSORS; REFERENCE VALUES;

EID: 13944284126     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-861035     Document Type: Article

References (24)

1. Goodner CJ, Walike BC, Koerker DJ, Ensinck JW, Brown AC, Chideckel EW, Palmer J, Kalnasy L. Insulin, glucagon and glucose exhibit synchronous, sustained oscillations in fasting monkeys. Science 1977; 195: 177-179
2. Lang DA, Matthews DR, Peto J, Turner RC. Cyclic oscillations of basal plasma glucose and insulin concentrations in human beings. N Engl J Med 1979; 301: 1023-1027
3. Juhl CB, Porksen N, Sturis J, Prange A, Veldhuis JD, Pincus SM, Fineman MS, Schmitz O. High frequency oscillations in circulating amylin concentrations in healthy humans. Am J Physiol 2000; 278: E484-490
4. Lang DA, Matthews DR, Burnett M, Turner RC. Brief, irregular oscillations of basal plasma insulin and glucose concentrations in diabetic man. Diabetes 1981; 30: 435-439
5. Polonsky KS, Given BD, Hirsch LJ, Tillil H, Shapiro ET, Beebe C, Frank BH, Galloway JA, van Cauter E. Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus. N Engl J Med 1988; 318: 1231-1239
6. O'Rahilly S, Turner RC, Matthews DR. Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes. N Engl J Med 1988; 318: 1225-1230
7. Schmitz O, Porksen N, Nyholm B, Skjaerbaek C, Butler PC, Veldhuis JD, Pincus SM. Disorderly and nonstationary insulin secretion in relatives of patients with NIDDM. Am J Physiol 1997; 272: E218-26
8. Bratusch MarrainPR, Komjati M, Waldhausl WK. Efficacy of pulsatile vs. continuous insulin administration on hepatic glucose production and glucose utilization in type I diabetic humans. Diabetes 1986; 35: 922-926
9. Paolisso G, Scheen AJ, Albert A, Lefebvre PJ. Effects of pulsatile delivery of insulin and glucagon in humans. Am J Physiol 1989; 257: E686-E696
10. Matthews DR, Naylor BA, Jones RG, Ward GM, Turner RC. Pulsatile insulin has greater hypoglycemic effect than continuous delivery. Diabetes 1983; 32: 617-621
11. Courtney CH, Atkinson AB, Ennis CN, Sheridan B, Bell PM. Comparison of the priming effects of pulsatile and continuous insulin delivery on insulin action in man. Metabolism 2003; 52: 1050-1055
12. Chou HF, Berman N, Ipp E. Evidence for pancreatic pacemaker for insulin oscillations in low-frequency range. Am J Physiol 1994; 266: R1786-R1791
13. Porksen NK, Juhl CB, Grøfte T, Hollingdal M, Sturis J, Veldhuis JD, Schmitz O. Induction of rapid insulin secretion in healthy humans by periodic glucose insfusion. Diabetes 1998; suppl (1), abstract nr992
14. Vilsboll T, Toft-Nielsen MB, Krarup T, Madsbad S, Dinesen B, Holst JJ. Evaluation of beta-cell secretory capacity using glucagon-like peptide 1. Diabetes Care 2000; 23(6): 807-812
15. Andersen L, Dinesen B, Jorgensen PN, Poulsen F, Roder ME. Enzyme immunoassay for intact human insulin in serum or plasma. Clin Chem 1993; 39: 578-582
16. Polonsky KS, Licinio-Paixao J, Given BD, Pugh W, Rue P, Galloway J, Karrison T, Frank B. Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type I diabetic patients. J Clin Invest 1986; 77(1): 98-105
17. Van Cauter E, Mestrez F, Sturis J, Polonsky KS. Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance. Diabetes 1992; 41: 368-377
18. Eaton RP, Allen RC, Schade DS, Erickson KM, Standefer J. Prehepatic insulin production in man: kinetic analysis using peripheral connecting peptide behavior. J Clin Endocrinol Metab 1980; 51: 520-528
19. Chatfield C. The analysis of time series. An introduction. 5th ed. London: Chapman and Hall, 1996
20. Smith CP, Tarn AC, Thomas JM, Overkamp D, Corakci A, Savage MO, Gale EA. Between and within subject variation of the first phase insulin response to intravenous glucose. Diabetologia 1988; 31: 123-125
21. Daniel S, Noda M, Straub SG, Sharp GW. Identification of the docked granule pool responsible for the first phase of glucose-stimulated insulin secretion. Diabetes 1999; 48: 1686-1690
22. Bratanova-Tochkova TK, Cheng H, Daniel S, Gunawardana S, Liu YJ, Mulvaney-Musa J, Schermerhorn T, Straub SG, Yajima H, Sharp GW. Triggering and augmentation mechanisms, granule pools, and biphasic insulin secretion. Diabetes 2002; 51 Suppl 1: S83-S90
23. Fichaux F, Bonnafous R. Responsiveness and memory of the pancreatic B-cells to the insulin secretagogues D-glucose and L-arginine in pre-diabetic and diabetic rabbits. Pancreas 1992; 7: 585-594
24. Porksen N, Juhl CB, Hollingdal M, Pincus SM, Sturis J, Veldhuis JD, Schmitz O. Concordant induction of rapid in vivo pulsatile insulin secretion by recurrent punctuated glucose infusions. Am J Physiol 2000; 278: E162-170