Aglycon specificity profiling of α-glucosidases using synthetic probes

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 5, 2005, Pages 1489-1492

  Hakamata, Wataru ^a,d   Muroi, Makoto ^a   Kadokura, Kazunari ^a   Nishio, Toshiyuki ^b   Oku, Tadatake ^b   Kimura, Atsuo ^c   Chiba, Seiya ^c   Takatsuki, Akira ^a  

^a INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^b NIHON UNIVERSITY   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Aglycon specificity; ER processing glucosidase; Inhibitor; Glucosidase

Indexed keywords

2,6 ANHYDRO 1 DEOXY 1 [(1 OXOPENTYL 5 HYDROXY)AMINO] DEXTRO GLYCERO DEXTRO IDOHEPTITOL; ALPHA GLUCOSIDASE; ALPHA GLUCOSIDASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME INHIBITION; HYDROGEN BOND; IC 50; MOLECULAR PROBE; NONHUMAN; REACTION ANALYSIS; SACCHAROMYCES CEREVISIAE; SYNTHESIS;

EID: 13944284104     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.12.086     Document Type: Article

References (30)

1. S. Chiba Handbook of amylases and related enzymes Amylase Research Society of Japan, Ed. 1988 Pergamon Oxford pp 104-116
2. T.P. Frandesn, and B. Svensson Plant Mol. Biol. 37 1998 1
3. B. Henrissat Biochem. J. 280 1991 309
4. B. Henrissat, and A. Bairoch Biochem. J. 293 1993 781
5. B. Henrissat, and A. Bairoch Biochem. J. 316 1996 695
6. S. Chiba Biosci. Biotechnol. Biochem. 61 1997 1233
7. A. Kimura, M. Takata, Y. Fukushi, H. Mori, H. Matsui, and S. Chiba Biosci. Biotechnol. Biochem. 61 1997 1091
8. A. Kimura Trends Glycosci. Glycotechnol. 12 2000 373
9. M. Okuyama, A. Okuno, N. Shimizu, H. Mori, A. Kimura, and S. Chiba Eur. J. Biochem. 268 2001 2270
10. A. Mehta, N. Zitzmann, P.M. Rudd, T.M. Block, and R.A. Dwek FEBS Lett. 430 1998 17
11. A. Herscovics Biochim. Biophys. Acta 1426 1999 275
12. C.M. De Praeter, G.J. Gerwig, E. Bause, L.K. Nuytinck, J.F.G. Vliegenthart, W. Breuer, J.P. Kamerling, M.F. Espeel, J.J.R. Martin, A.M. De Paepe, N.W.C. Chan, G.A. Dacremont, and R.N. Van Coster Am. J. Human Genet. 66 2000 1744
13. C. Braun, G.D. Brayer, and S.G. Withers J. Biol. Chem. 270 1995 26778
14. R.A. Dwek, T.D. Butters, F.M. Platt, and N. Zitzmann Nat. Rev. Drug Discovery 1 2002 65
15. W. Hakamata, T. Nishio, and T. Oku J. Appl. Glycosci. 46 1999 459
16. W. Hakamata, T. Nishio, R. Sato, T. Mochizuki, K. Tsuchiya, M. Yasuda, and T. Oku J. Carbohydr. Chem. 19 2000 359
17. T. Nishio, W. Hakamata, A. Kimura, S. Chiba, A. Takatsuki, R. Kawachi, and T. Oku Carbohydr. Res. 337 2002 629
18. W. Hakamata, T. Nishio, and T. Oku Carbohydr. Res. 324 2000 107
19. T. Nishio, Y. Miyake, H. Tsujii, W. Hakamata, K. Kadokura, and T. Oku Biosci. Biotechnol. Biochem. 60 1996 1233
20. W. Hakamata, M. Muroi, T. Nishio, T. Oku, and A. Takatsuki J. Carbohydr. Chem. 23 2004 27
21. 8 were assayed as described previously
22. S. Takewaki, S. Chiba, A. Kimura, H. Matsui, and Y. Koike Agric. Biol. Chem. 44 1980 731
23. A. Kimura, H. Matsui, M. Honma, and S. Chiba J. Biochem. 112 1992 127
24. Honeybee isozyme III is the recombinant enzyme (unpublished data)
25. S. Chiba, S. Inomata, H. Matsui, and T. Shimomura Agric. Biol. Chem. 42 1978 241
26. S. Chiba, and T. Shimomura Agric. Biol. Chem. 39 1975 1033
27. A. Kita, H. Matsui, A. Kimura, M. Takata, and S. Chiba Agric. Biol. Chem. 55 1991 2327
28. E. Tsujii, M. Muroi, N. Shiragami, and A. Takatsuki Biophys. Biophys. Res. Commun. 220 1996 459
29. G. Legler Adv. Carbohydr. Chem. Biochem. 48 1990 319
30. R. Hoos, A. Vasella, Rupitz, and S.G. Withers Carbohydr. Res. 298 1997 291