Effects of progesterone and estrogen on endothelial dysfunction in porcine coronary arteries

Journal of Surgical Research

Volumn 124, Issue 1, 2005, Pages 104-111

  Cox, Mitchell W ^a   Fu, Weiping ^a   Chai, Hong ^a   Paladugu, Ramesh ^a   Lin, Peter H ^a   Lumsden, Alan B ^a   Yao, Qizhi ^a   Chen, Changyi ^a,b  

^a HOUSTON METHODIST HOSPITAL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Coronary arteries; Endothelial dysfunction; Estrogen; Porcine; Progesterone

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; BRADYKININ; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ESTROGEN; LUCIGENIN; PROGESTERONE;

ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY ENDOTHELIUM; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY DILATATION; ENDOTHELIUM INJURY; ESTROGEN THERAPY; FEMALE; HORMONE SUBSTITUTION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MYOGRAPHY; NONHUMAN; PRIORITY JOURNAL; SWINE; TISSUE CULTURE;

EID: 13944269954     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jss.2004.09.003     Document Type: Article

References (24)

1. D. Grady, S.M. Rubin, D.B. Petitti Hormone therapy to prevent disease and prolong life in post-menopausal women Ann. Intern. Med. 117 1992 1016
2. S. Hulley, D. Grady, T. Bush Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Reasearch Group JAMA 280 1998 605
3. Writing Group for the Women's Health Initiative Investigators Risks and benefits of estrogen plus progestin in healthy postmenopausal women JAMA 288 2002 321
4. M.E. Mendelsohn, R.H. Karas The protective effects of estrogen on the cardiovascular system N. Engl. J. Med. 340 1999 1801
5. S. Moncada, A. Higgs The larginine-nitric oxide pathway N. Engl. J. Med. 329 1993 2002
6. M. Gerhard, B.W. Walsh, A. Tawakol Estradiol therapy combined with progesterone and endothelium-dependent vasodilation in postmenopausal women Circulation 98 1998 1158
7. M.E. Mendelsohn, E. Nongenomic R-mediated activation of endothelial nitric oxide synthase How does it work? What Does it Mean? Circ. Res. 87 2000 956
8. A.M. McNeill, C. Zhang, F.Z. Stanczyk Estrogen increases endothelial nitric oxide synthase via estrogen receptors in rat cerebral blood vessels Stroke 33 2002 1685
9. H. Kawano, T. Motoyama, N. Hirai Effect of medroxyprogesterone acetate plus estradiol on endothelium-dependent vasodilation in post-menopausal women Am. J. Cardiol. 87 2001 238
10. B.S. Conklin, S.M. Surowiec, Z.G. Ren Effects of nicotine and cotanine on porcine arterial endothelial cell function J. Surg. Res. 95 2001 23
11. M.W. Radomski, S. Moncada Regulation of vascular homeostasis by nitric oxide Thromb. Haemost. 70 1993 36
12. S. Lamas, D. Perez-Sala, S. Moncada Nitric oxide From discovery to the clinic Trends Pharmacol. Sci. 19 1998 436
13. B.M. Babior The NADPH oxidase of endothelial cells IUBMB Life 50 2000 267
14. A.H. Wagner, T. Kohler, U. Ruckschloss Improvement of nitric oxide dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation Arterioscler. Thromb. Biol. 20 2000 61
15. T. Munzel, I.B. Afanasev, A.L. Kleschyov Detection of superoxide in vascular tissues Arterioscler. Thromb. Vasc. Biol. 22 2002 1761
16. M.E. Mendelsohn Genomic and non-genomic effects of estrogen in the vasculature Am. J. Cardiol. 90 2002 F3
17. T.A. Spencer, H. Chai, W. Fu Estrogen blocks the effects of homocysteine on endothelium dependent vasorelaxation in porcine coronary arteries J. Surg. Res. 118 2004 83
18. C. Chen, B.S. Conklin, Z. Ren Homocysteine decreases endothelium- dependent vasorelaxation in porcine arteries J. Surg. Res. 102 2002 22
19. R. Paladugu, W. Fu, B.S. Conklin HIV-Tat protein causes endothelial dysfunction in porcine coronary arteries J. Vasc. Surg. 38 2003 549
20. W. Fu, B.S. Conklin, P.H. Lin Red wine prevents homocysteine-induced endothelial dysfunction in porcine coronary arteries J. Surg. Res. 115 2003 82
21. H. Singer, M. Peach Calcium- and endothelial-mediated vascular smooth muscle relaxation in rabbit aorta Hypertension 3 1982 19
22. L.R. Pelc, G.J. Gross, D.C. Warltier Mechanism of coronary vasodilation produced by bradykinin Circulation 83 1991 2048
23. D. Sumi, T. Hayashi, H. Matsui-Hirai 17h-Estradiol inhibits NADPH oxidase activity through the regulation of p47phox mRNA and protein expression in THP-1 cells Biochim. Biophys. Acta 1640 2003 113
24. A.P.V. Dantas, R.C.A. Tostes, Z.B. Fortes In vivo evidence for antioxidant potential of estrogen in microvessels of female spontaneously hypertensive rats Hypertension 39 2002 405