The comparative efficacy of stabilized stannous fluoride/sodium hexametaphosphate dentifrice and sodium fluoride/triclosan/copolymer dentifrice for the control of gingivitis: A 6-month randomized clinical study

Journal of Periodontology

Volumn 75, Issue 12, 2004, Pages 1592-1599

  Archila, Luis ^a   Bartizek, Robert D ^b   Winston, J Leslie ^b   Biesbrock, Aaron R ^b   McClanahan, Stephen F ^b   He, Tao ^b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

Bleeding, therapy; Clinical trials, randomized; Comparison studies; Dentifrices therapeutic use; Fluorides therapeutic use; Gingivitis therapy; Triclosan therapeutic use

Indexed keywords

FLUORIDE SODIUM; GANTREZ COPOLYMER; HEXAMETAPHOSPHATE SODIUM; STANNOUS FLUORIDE; TOOTHPASTE; TRICLOSAN;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL EXAMINATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; GINGIVA BLEEDING; GINGIVITIS; HEALTH CARE ORGANIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PREVENTIVE DENTISTRY; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; TIME; TOOTH BRUSHING; TREATMENT OUTCOME; UNITED STATES;

ADOLESCENT; ADULT; AGED; ANALYSIS OF VARIANCE; ANTI-INFECTIVE AGENTS, LOCAL; DENTIFRICES; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; FEMALE; GINGIVITIS; HUMANS; MALE; MALEATES; MIDDLE AGED; PERIODONTAL INDEX; PHOSPHATES; POLYVINYLS; SODIUM FLUORIDE; TIN FLUORIDES; TRICLOSAN;

EID: 13844316608     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2004.75.12.1592     Document Type: Article

References (39)

1. Page RC. The etiology and pathogenesis of periodontitis. Compend Contin Educ Dent 2002;23(5 Suppl.):11-14.
2. He T, Nishihara T, Demuth DR, Ishikawa I. A novel insertion sequence increases the expression of leukotoxicity in Actinobacillus actinomycetemcomitans clinical isolates. J Periodontol 1999;70:1261-1268.
3. He T, Hayashi J, Yamamoto M, Ishikawa I. Genotypic characterization of Actinobacillus actinomycetemcomitans isolated from periodontitis patients by arbitrarily primed pollymerase chain reaction. J Periodontol 1998;69:69-75.
4. Kinane DF, Hodge PJ. Periodontal disease in children and adolescents: Introduction and classification. Periodontol 2000 2001;26:7-15.
5. Kornman KS, Löe H. The role of local factors in the etiology of periodontal disease. Periodontol 2000 1993;2:83-97.
6. Drisko CH. Nonsurgical periodontal therapy. Periodontol 2000 2001;25:77-88.
7. Jeffcoat MK. Prevention of periodontal diseases in adults: Strategies for the future. Prev Med 1994;23:704-708.
8. Oral Health of United States Adults. The National Survey of Oral Health in U.S. Employed Adults and Seniors. 1985-86. Washington, DC: Public Health Service; 1987. NIH publication no. 87-2868.
9. American Academy of Periodontology. Epidemiology of periodontal diseases (position paper). J Periodontol 1996; 67:935-945.
10. Stamm JW. Epidemiology of gingivitis. J Clin Periodontol 1986;13:360-370.
11. Brown LJ, Löe H. Prevalence, extent, severity and progression of periodontal disease. Periodontol 2000 1993; 2:57-71.
12. Ravussin E, Bouchard C. Human genomics and obesity: Finding appropriate drug targets. Eur J Pharmacol 2000; 410:131-145.
13. Ainamo J. Control of plaque by chemical agents. J Clin Periodontol 1977;4:23-35.
14. Scheie AAA. Modes of action of currently known chemical antiplaque agents other than chlorhexidine. J Dent Res 1989;68(Spec. Issue):1609-1616.
15. Beiswanger BB, McClanahan SF, Bartizek RD, Lanzalaco AC, Bacca LA, White DJ. The comparative efficacy of stabilized stannous fluoride dentifrice, peroxide/baking soda dentifrice and essential oil mouthrinse for the prevention of gingivitis. J Clin Dent 1997;8(2 Spec. No.): 46-53.
16. McClanahan SF, Beiswanger BB, Bartizek RD, Lanzalaco AC, Bacca L, White DJ. A comparison of stabilized stannous fluoride dentifrice and triclosan/copolymer dentifrice for efficacy in the reduction of gingivitis and gingival bleeding: Six-month clinical results. J Clin Dent 1997;8(2 Spec. No.):39-45.
17. Saxton CA, Lane RM, van der Ouderaa F. The effects of a dentifrice containing a zinc salt and a non-cationic antimicrobial agent on plaque and gingivitis. J Clin Periodontol 1987;14:144-148.
18. Palomo F, Wantland L, Sanchez A, Volpe AR, McCool J, DeVizio W. The effect of three commercially available dentifrices containing triclosan on supragingival plaque formation and gingivitis: A six month clinical study. Int Dent J 1994;44(1 Suppl. 1):75-81.
19. Mankodi S, Walker C, Conforti N, DeVizio W, McCool JJ, Volpe AR. Clinical effect of a triclosan-containing dentifrice on plaque and gingivitis: A six-month study. Clin Prev Dent 1992;14:4-10.
20. Tinanoff N. Review of the antimicrobial action of stannous fluoride. J Clin Dent 1990;2:22-27.
21. Tinanoff N, Manwell MA, Zameck RL, Grasso JE. Clinical and microbiological effects of daily brushing with either NaF or SnF2 gels in subjects with fixed or removable dental prostheses. J Clin Periodontol 1989;16:284-290.
22. Tinanoff N. Progress regarding the use of stannous fluoride in clinical dentistry. J Clin Dent 1995;6(Spec. No.)37-40.
23. White DJ, Gerlach RW. Anticalculus effects of a novel, dual-phase polypyrophosphate dentifrice: Chemical basis, mechanism, and clinical response. J Contemp Dent Pract 2000;1:1-19.
24. Baig AA, Kozak KM, Cox ER, Zoladz JR, Mahony L, White DJ. Laboratory studies on the chemical whitening effects of a sodium hexametaphosphate dentifrice. J Clin Dent 2002;13:19-24.
25. Liu H, Segreto VA, Baker RA, Vastola KA, Ramsey LL, Gerlach RW. Anticalculus efficacy and safety of a novel whitening dentifrice containing sodium hexametaphosphate: A controlled six-month clinical trial. J Clin Dent 2002;13:25-28.
26. Gerlach RW, Liu H, Prater ME, Ramsey LL, White DJ. Removal of extrinsic stain using a 7.0% sodium hexametaphosphate dentifrice: A randomized clinical trial. J Clin Dent 2002;13:6-9.
27. Council of Scientific Affairs. Acceptance Program Guidelines: Chemotherapeutic Products for Control of Gingivitis. Chicago: American Dental Association; July 1997.
28. Löe H, Silness J. Periodontal disease in pregnancy. I. Prevalence and Severity. Acta Odontol Scand 1963;21: 533-551.
29. Lehnhoff RW, Grainger RM. Use of analysis of covariance in periodontal clinical trials. J Periodontal Res 1974; 14(Suppl.):143-159.
30. Johnson PO, Neyman J. Tests of certain linear hypotheses and their applications to some educational problems. Stat Res Memoirs 1936;1:57-93.
31. Perlich MA, Bacca LA, Bollmer BW, et al. The clinical effect of a stabilized stannous fluoride dentifrice on plaque formation, gingivitis and gingival bleeding: A six-month study. J Clin Dent 1995;6(Spec. No.):54-58.
32. Boyd RL, Chun YS. Eighteen-month evaluation of the effects of a 0.4% stannous fluoride gel on gingivitis in orthodontic patients. Am J Orthod Dentofacial Orthop 1994;105:35-41.
33. Chikte UM, Pochee E, Rudolph MJ, Reinach SG. Evaluation of stannous fluoride and chlorhexidine sprays on plaque and gingivitis in handicapped children. J Clin Periodontol 1991;18:281-286.
34. Wolff LF, Pihlstrom BL, Bakdash MB, Aeppli DM, Bandt CL. Effect of toothbrushing with 0.4% stannous fluoride and 0.22% sodium fluoride gel on gingivitis for 18 months. J Am Dent Assoc 1989;119:283-289.
35. Williams C, McBride S, Bolden TE, et al. Clinical efficacy of an optimized stannous fluoride dentifrice, Part 3: A 6-month plaque/gingivitis clinical study, southeast USA. Compend Contin Educ Dent 1997;18(Spec. No.):16-20.
36. Mankodi S, Petrone DM, Battista G, et al. Clinical efficacy of an optimized stannous fluoride dentifrice, Part 2: A 6-month plaque/gingivitis clinical study, northeast USA. Compend Contin Educ Dent 1997;18(Spec. No.): 10-15.
37. Beiswanger BB, Doyle PM, Jackson RD, et al. The clinical effect of dentifrices containing stabilized stannous fluoride on plaque formation and gingivitis - a six-month study with ad libitum brushing. J Clin Dent 1995;6(Spec. No.):46-53.
38. Lang NP. Epidemiology of periodontal disease. Arch Oral Biol 1990;35:(Suppl.):9S-14S.
39. Lindhe J, Koch G. The effect of supervised oral hygiene on the gingiva of children. Progression and inhibition of gingivitis. J Periodontal Res 1966;1:260-267.