DNA degradation by the mixture of copper and catechol is caused by DNA-copper-hydroperoxo complexes, probably DNA-Cu(I)OOH

Environmental and Molecular Mutagenesis

Volumn 36, Issue 1, 2000, Pages 5-12

  Schweigert, Nina ^a   Acero, Juan L ^b   Von Gunten, Urs ^a   Canonica, Silvio ^a   Zehnder, Alexander J B ^a   Eggen, Rik I L ^a  

^a SWISS FEDERAL INSTITUTE OF AQUATIC SCIENCE AND TECHNOLOGY   (Switzerland)

^b UNIVERSITY OF EXTREMADURA   (Spain)

Author keywords

Catechol; DNA degradation; DNA copper hydroperoxo complex; Free hydroxyl radicals; Reactive oxygen species; Singlet oxygen

Indexed keywords

4 CHLOROBENZOIC ACID; CATECHOL; COPPER CHLORIDE; COPPER COMPLEX; GUANINE; HYDROXYL RADICAL; METHYLENE BLUE; PIPERIDINE DERIVATIVE; PLASMID DNA; REACTIVE OXYGEN METABOLITE; SCAVENGER; SINGLET OXYGEN;

ARTICLE; COMPLEX FORMATION; CONCENTRATION RESPONSE; DNA BINDING; DNA DEGRADATION; INHIBITION KINETICS; IONIC STRENGTH; NONHUMAN; REACTION ANALYSIS;

CATECHOLS; COPPER; DNA; DNA DAMAGE; FREE RADICAL SCAVENGERS; GUANINE; HYDROXYL RADICAL; OSMOLAR CONCENTRATION; PIPERIDINES; REACTIVE OXYGEN SPECIES;

EID: 0033859747     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/1098-2280(2000)36:1<5::AID-EM2>3.0.CO;2-4     Document Type: Article

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