ABL-MYC retroviral infection elicits bone marrow plasma cell tumors in Bcl-XL transgenic mice

Leukemia Research

Volumn 29, Issue 4, 2005, Pages 435-444

  Linden, Michael ^a,b   Kirchhof, Nicole ^b   Kvitrud, Mary ^b   Ness, Brian Van ^b  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

ABL MYC; Bcl XL; Multiple Myeloma

Indexed keywords

ABELSON KINASE; MYC PROTEIN; PROTEIN BCL XL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE LESION; BONE MARROW; CELL POPULATION; CONTROLLED STUDY; GRANULOCYTIC SARCOMA; HUMAN; IMMUNOGLOBULIN GENE; LATENT PERIOD; MOLECULAR CLONING; MOUSE; NONHUMAN; PLASMACYTOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETROVIRUS INFECTION; SOMATIC HYPERMUTATION; SURVIVAL TIME; TRANSGENIC MOUSE; VIRUS CARCINOGENESIS;

EID: 13844281190     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2004.09.007     Document Type: Article

References (21)

1. W.S. Dalton, P.L. Bergsagel, W.M. Kuehl, K.C. Anderson, and J.L. Harousseau Multiple myeloma Hematology (Am Soc Hematol Educ Program) 2001 157 177
2. H. Kubagawa, L.B. Vogler, J.D. Capra, M.E. Conrad, A.R. Lawton, and M.D. Cooper Studies on the clonal origin of multiple myeloma. Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point of expression in B-cell differentiation J Exp Med 150 1979 792 807
3. D. Largaespada, D. Kaehler, E. Weissinger, H. Mischak, F. Mushinski, and R. Risser The activity of an ABL-MYC retrovirus in fibroblast cell lines and in lymphocytes Curr Top Microbiol Immunol 166 1990 91 96
4. D.A. Largaespada, D.A. Kaehler, H. Mishak, E. Weissinger, M. Potter, and J.F. Mushinski A retrovirus that expresses v-abl and c-myc oncogenes rapidly induces plasmacytomas Oncogene 7 1992 811 819
5. E.M. Weissinger, D. Largaespada, S.J. Smith-Gill, R. Risser, J.F. Mushinski, and H. Mischak A retrovirus expressing v-abl and c-myc induces plasmacytomas in 100% of adult pristane-primed BALB/c mice Curr Top Microbiol Immunol 166 1990 121 127
6. M.A. Linden, N. Kirchhof, C.S. Carlson, and B.G. Van Ness Targeted overexpression of Bcl-XL in B-lymphoid cells results in lymphoproliferative disease and plasma cell malignancies Blood 103 2004 2779 2786
7. P.L. Green, W.W. Lamph, J. Dudley, A. Arfsten, R. Risser, and L.L. Lanier Phenotypic variation in clonal Abelson virus lymphoma cells J Immunol 134 1985 1268 1275
8. C.J. Jolly, N. Klix, and M.S. Neuberger Rapid methods for the analysis of immunoglobulin gene hypermutation: application to transgenic and gene targeted mice Nucleic Acids Res 25 1997 1913 1919
9. J.P. McDonald, E.G. Frank, B.S. Plosky, I.B. Rogozin, C. Masutani, and F. Hanaoka 129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation J Exp Med 198 2003 635 643
10. E.M. Weissinger, H. Mischak, D.A. Largaespada, D.A. Kaehler, T. Mitchell, and S.J. Smith-Gill Induction of plasmacytomas secreting antigen-specific monoclonal antibodies with a retrovirus expressing v-abl and c-myc Proc Natl Acad Sci U S A 88 1991 8735 8739
11. J. Bachl, C. Carlson, V. Gray-Schopfer, M. Dessing, and C. Olsson Increased transcription levels induce higher mutation rates in a hypermutating cell line J Immunol 166 2001 5051 5057
12. C.J. Paige, P.W. Kincade, P. Ralph, and Murine B cell leukemia line with inducible surface immunoglobulin expression J Immunol 121 1978 641 647
13. Q. Chen, J. Turner, A.J. Watson, and C. Dive v-Abl protein tyrosine kinase (PTK) mediated suppression of apoptosis is associated with the up-regulation of Bcl-XL Oncogene 15 1997 2249 2254
14. E.J. Noronha, K.H. Sterling, and K.L. Calame Increased expression of Bcl-xL and c-Myc is associated with transformation by Abelson murine leukemia virus J Biol Chem 278 2003 50915 50922
15. F. Li, F. Jin, A. Freitas, P. Szabo, and M.E. Weksler Impaired regeneration of the peripheral B cell repertoire from bone marrow following lymphopenia in old mice Eur J Immunol 31 2001 500 505
16. W.C. Cheung, J.S. Kim, M.A. Linden, L. Peng, B.G. Van Ness, R. Polakiewicz, and S. Janz Novel targeted deregulation of c-Myc cooperates with Bcl-X(L) to cause plasma cell neoplasms in mice J Clin Invest 113 2004 1763 1773
17. P.N. Anderson, and M. Potter Induction of plasma cell tumours in BALB-c mice with 2,6,10,14-tetramethylpentadecane (pristane) Nature 222 1969 994 995
18. M. Potter Plasmacytomas in mice Semin Oncol 13 1986 275 281
19. M. Potter, and F. Wiener Plasmacytomagenesis in mice: model of neoplastic development dependent upon chromosomal translocations Carcinogenesis 13 1992 1681 1697
20. H. Rosenbaum, A.W. Harris, M.L. Bath, J. McNeall, E. Webb, and J.M. Adams An E mu-v-abl transgene elicits plasmacytomas in concert with an activated myc gene EMBO J 9 1990 897 905
21. A.L. Kovalchuk, J.S. Kim, S.S. Park, A.E. Coleman, J.M. Ward, and H.C. Morse 3rd. IL-6 transgenic mouse model for extraosseous plasmacytoma Proc Natl Acad Sci U S A 99 2002 1509 1514