FRET-FCS as a tool to evaluate the stability of oligonucleotide drugs after intracellular delivery

Journal of Controlled Release

Volumn 103, Issue 1, 2005, Pages 259-271

  Remaut, K ^a   Lucas, B ^a   Braeckmans, K ^a   Sanders, N N ^a   De Smedt, S C ^a   Demeester, J ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Antisense oligonucleotides; Fluorescence Correlation Spectroscopy (FCS); FRET; Intracellular degradation

Indexed keywords

CELLS; DEGRADATION; DETECTORS; DRUG PRODUCTS; ENERGY TRANSFER; FLUORESCENCE; RESONANCE; SPECTROSCOPIC ANALYSIS;

FLUORESCENCE CORRELATION SPECTROSCOPY (FCS); FLUORESCENCE RESONANCE ENERGY TRANSFER (FRET); INTRACELLULAR DEGRADATION; INTRACELLULAR FLUORESCENCE;

CONTROLLED DRUG DELIVERY;

ANTISENSE OLIGONUCLEOTIDE; FLUORESCENT DYE; RHODAMINE;

ACCURACY; ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG DEGRADATION; FLUORESCENCE ANALYSIS; FLUORESCENCE CORRELATION SPECTROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; INTRACELLULAR SPACE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CERCOPITHECUS AETHIOPS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE TRANSFER TECHNIQUES; INTRACELLULAR FLUID; OLIGONUCLEOTIDES; VERO CELLS;

EID: 13844274900     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.11.019     Document Type: Article

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