The use of recombinant factor VIIa in a patient with essential thrombocythaemia with uncontrolled surgical bleeding

Thrombosis and Haemostasis

Volumn 93, Issue 2, 2005, Pages 383-384

  Cervera, José Sanchis ^a,c   Mena Durán, Armando V ^b   Piqueras, Cristina Sanchis ^a  

^a HOSPITAL DE LA PLANA   (Spain)

^b BURNHAM INSTITUTE   (United States)

^c NONE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; AMINOCAPROIC ACID; COLLAGEN; FIBRINOGEN; HYDROXYUREA; RECOMBINANT BLOOD CLOTTING FACTOR 7A;

AGED; ARTICLE; BLEEDING; BLEEDING TIME; BLOOD CLOTTING TIME; BLOOD PRESSURE; BLOOD TRANSFUSION; CASE REPORT; DRUG WITHDRAWAL; FEMALE; FIBRINOGEN BLOOD LEVEL; HEMOGLOBIN DETERMINATION; HUMAN; HYPERTENSION; HYSTERECTOMY; INTENSIVE CARE UNIT; LEUKOCYTE COUNT; PALLOR; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTHROMBIN TIME; PULSE RATE; RETREATMENT; THROMBOCYTE COUNT; THROMBOCYTHEMIA; URINARY TRACT INFECTION; UTERUS PROLAPSE;

EID: 13844267678     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1616256     Document Type: Article

References (10)

1. Barbui T, Finazzi G. Management of essential thrombocythemia. Crit Rev Oncol Hematol 1999; 29: 257-66.
2. el Kassar N, Hetet G, Li Y, et al. Clonal analysis of haemopoietic cells in essential thrombocythaemia. Br J Haematol 1995; 90, 131-7.
3. Fialkow PJ, Faguet GB, Jacobson RJ, et al. Evidence that essential thrombocythemia is a clonal disorder with origin in a multipotent stem cell. Blood 1981; 58: 916-9.
4. Lisman T, Adelmeijer J, Heijnen HF, et al. Recombinant factor VIIa restores aggregation of alphaIIb-beta3-deficient platelets via tissue factor independent fibrin generation. Blood 2004; 103: 1720-7.
5. Lisman T, Moschatsis S, Adelmeijer J, et al. Recombinant factor VIIa enhances deposition of platelets with congenital or acquired alpha IIb beta 3 deficiency to endothelial cell matrix and collagen under conditions of flow via tissue factor-independent thrombin generation. Blood 2003; 101: 1864-70.
6. Peters M, Heijboer H. Treatment of a patient with Bernard-Soulier syndrome and recurrent nosebleeds with recombinant factor VIIa. Thromb Haemost 1998; 80: 352.
7. Poon MC, Demers C, Jobin F, et al. Recombinant factor VIIa is effective for bleeding and surgery in patients with Glanzmann thrombasthenia. Blood 1999; 94: 3951-3.
8. Revesz T, Arets B, Bierings M, et al. Recombinant factor VIIa in severe uremic bleeding. Thromb Haemost 1998; 80: 353.
9. Roberts HR. Recombinant factor VIIa: a general hemostatic agent? Yes. J Thromb Haemost 2004; 2: 1691-4.
10. van Genderen PJ, Budde U, Michiels JJ, et al. The reduction of large von Willebrand factor multimers in plasma in essential thrombocythaemia is related to the platelet count. Br J Haematol 1996; 93: 962-5.