Radiosensitivity of peripheral blood lymphocytes obtained from patients with cancers of the breast, head and neck or cervix as determined with a micronucleus assay

Journal of Radiation Research

Volumn 45, Issue 4, 2004, Pages 535-541

  Ban, Sadayuki ^a   Konomi, Chika ^a   Iwakawa, Mayumi ^a   Yamada, Shigeru ^b   Ohno, Tatsuya ^b   Tsuji, Hiroshi ^b   Noda, Syuhei ^a   Matui, Yoshifumi ^a   Harada, Yoshinobu ^a   Cologne, John B ^c   Imai, Takashi ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^c RADIATION EFFECTS RESEARCH FOUNDATION   (Japan)

Author keywords

Cancer patients; Chemotherapy; Micronucleus assay; Radiation sensitivity; Radiotherapy

Indexed keywords

BLOOD; DISEASES; LYMPHOCYTES; RADIATION; RADIOTHERAPY;

BLOCKINGS; CANCER PATIENTS; CERVICAL CANCERS; HEAD AND NECK; HEALTHY CONTROLS; IN-VITRO; MICRONUCLEUS ASSAY; MICRONUCLEUS FREQUENCIES; PERIPHERAL BLOOD LYMPHOCYTES; RADIATION SENSITIVITY;

CHEMOTHERAPY;

ARTICLE; BREAST CARCINOMA; CANCER CLASSIFICATION; CONTROLLED STUDY; CYTOKINE RELEASE; EVALUATION; FEMALE; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MICRONUCLEUS TEST; PAPILLOMA VIRUS; PERIPHERAL LYMPHOCYTE; RADIOSENSITIZATION; UTERINE CERVIX CARCINOMA;

PAPILLOMAVIRUS;

EID: 13844267443     PISSN: 04493060     EISSN: None     Source Type: Journal    
DOI: 10.1269/jrr.45.535     Document Type: Article

References (26)

1. Fenech, M. and Morley, A. A. (1985) Measurements of micronuclei in lymphocytes, Mutation Res. 149: 475-483.
2. 2 phase X-irradiation of cells from cancer prone individuals implicates deficiency in DNA repair, Proc. Natl. Acad. Sci. USA 80: 5612-5616.
3. Ban, B., Cologne, J. B., Fujita, S. and Awa, A. A. (1993) Radiosensitivity of atomic bomb survivors as determined with a micronucleus assay, Radiat. Res. 134: 170-178.
4. 2 phase X irradiation in relation to DNA repair and radiosensitivity in a cancer-prone family with Li-Fraumeni syndrome, Radiat. Res. 136: 236-240.
5. 2 phase X-irradiation of cells from retinoblastoma patients, Cancer Genet. Cytogenet. 88: 43-48.
6. Scott, D., Barber, J. B. P., Levine, E. L., Burrill, W. and Roberts, S. A. (1998) Radiation-induced micronucleus induction in lymphocytes identifies a high frequency of radiosensitive cases among breast cancer patients: a test for predisposision? (1998) Brit. J. Cancer 77: 614-620.
7. Scott, D., Barber, J. B. P., Spreadborough, A. R., Burrill, W. and Roberts, S. A. (1999) Increased chromosomal radiosensitivity in breast cancer patients: a comparison of two assays, Int. J. Radiat. Bio. 75: 1-10.
8. Scott,, D., Barber, J., Papworth, R., Burrill, W., Slevin, N. and Roberts, S. (2001)The use of the micronucleus assay in predicting cancer risk and response to radiotherapy, Mutation Res. 483 (Supple. 1): S52.
9. 2-phase assays for human blood lymphocytes as biomarkers of individual sensitivity to ionizing radiation: limitations imposed by intraindividual variability, Radiat. Res. 157: 472-477.
10. Bondy, M. L., Wang, L.-E., El-Zein, R., de Andrade, M., Selvan, M. S., Bruner, J. M. Levin, V. A., Yung, W. K. A., Adatto, P. and Wei, Q. (2001) γ-radiation sensitivity and risk of glioma, J. Nat. Cancer Inst. 93: 1553-1557.
11. Lee, T.-K., Allison, R. R., O'Brien, K. F., Naves, J. L., Karlsson, U. L. and Wiley, Jr., A. L. (2002) Persistence of micronuclei in lymphocytes of cancer patients after radiotherapy, Radiat. Res. 157: 678-684.
12. Fitzek, M. M., Dahlberg, W. K., Nagasawa, H., Mukai, S., Munzenrider, J. E. and Little, J. B. (2002) Unexpected sensitivity to radiation of fibroblasts from unaffected parents of children with hereditary retinoblastoma, Int. J. Cancer 99: 764-768.
13. Ban, S., Shinohara, T., Hirai, H., Moritaku, Y., Cologne, J. B. and MacPhee, D. J. (2001) Chromosomal instability in BRCA1- or BRCA2-defective human cancer cells detected by spontaneous micronucleus assay, Mutation Res. 474: 15-23.
14. Bonassi,S., Fenech, M., Lando, C., Lin, Y.-P., Ceppi, M., Chang, W. P., Holland, N., Kirsh-Volders, M., Zeiger, E., Ban, S., Barale, R., Bigatti, M. P., Bolognesi, C., Jia, C., Giorgio, M. D., Ferguson, L. R., Fucic, A., Lima, O. G., Hrelia, O., Krishnaja, A. P., Lee, T.-K., Migliore, L., Mikhalevich, L., Mirkova, E., Mosesso, P., Muller, W.-U., Odagiri, Y., Scarfi, M. R., Szabova, E., Vorobtsova, I., Vral, A. and Zijno, A. (2001) Human MicroNucleus Project: International database comparison for results with the cytokinesis-block micronucleus assay in human lymphocytes: I: Effect of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei, Environ. Mol. Mutagen. 37: 31-45.
15. Tindle, R. W. (2002) Immune evasion in human papillomavirus-associated cervical cancer, Nature Reviews 2: 59-65.
16. Butz, K., Geisen, C., Ullmann, A., Spitkovsky, D. and Hoppe-Seyler, F. (1996) Cellular responses of HPV-positive cancer cells to genotoxic anti-cancer agents: repression of E6/E7-oncogene expression and induction of apoptosis, Int. J. Cancer 68: 506-513.
17. Harima, Y., Sawada, S., Nagata, K., Sougawa, M. and Onishi, T. (2002) Human papilloma virus (HPV) DNA associated with prognosis of cervical cancer after radiotherapy, Int. J. Radiat. Oncol. Biol. Phys. 52: 1345-1351.
18. Olivieri, G., Bodycote, J. and Wolff, S. (1984) Adaptive response of human lymphocytes to low concentrations of radioactive thymidine, Science 223: 594-597.
19. Vijayalaxmi, Leal,, B. Z., Deahl, T. S., and Meltz, M. L. (1995) Variability in adoptive response to low dose radiation in human blood lymphocytes: consistent results from chromosome aberrations and micronuclei, Mutation. Res. 348: 45-50.
20. Gil, O. M., Oliveira, N. G., Rodrigues, A. S., Laires, A., Ferreira, T. C., Limbert, E. and Rueff, J. (2002) Possible transient adaptive response to mitomycin C in peripheral lymphocytes from thyroid cancer patients after iodine-131 therapy, Int. J. Cancer 102: 556-561.
21. Goode, E. L., Ulrich, C. M. and Potter, J. D. (2002) Polymorphisms in DNA repair genes and associations with cancer risk, Cancer Epidemiology Biomarkers & Prevention 11: 1513-1530.
22. Kuschel, B., Auranen, A., McBride, S., Novik, K. L., Antoniou, A., Lipscombe, J. M., Day, N. E., Easton, D. F., Ponder, B. A. J., Pharoah, P. D. P. and Dunning, A. (2002) Variants in DNA double-strand break repair genes and breast cancer susceptibility, Human Mol. Genet. 11: 1399-1407.
23. Winsey, S. L., Haldar, N. A., Marsh, H. P., Bunce, M., Marshall, S. E., Harris, A. L., Wojnarowska, F. and Welsh, K. I. (2000) A variant within the DNA repair gene XRCC3 is associated with the development of melanoma skin cancer, Cancer Res. 60: 5612-5616.
24. Shen, H., Sturgis, E. M., Dahlstrom, K. R., Zheng, Y., Spitz, M. R. and Wei, Q. (2002) A variant of the DNA repair gene XRCC3 and risk of squamous cell carcinoma of the head and neck: a case-control analysis, Int. J. Cancer 99: 869-872.
25. Rafii,, S., O'Regan, P., Xinarianos, G., Azmy, I., Stephenson, T., Reed, M., Meuth, M., Thacker, J. and Cox, A. (2002) A potential role for the XRCC2 R188H polymorphic site in DNA-damage repair and breast cancer, Human Mol. Genet. 11: 1433-1438.
26. Rodriguez-Lopez, R., Osorio, A., Sanchez-Pulido, L., Hoya, de la M., Barroso, A., Caldes, T. and Benitez, J. (2003) No mutations in the XRCC2 gene in BRCA1/2-negative high-risk breast cancer families, Int. J. Cancer 103: 136-137.