Fumonisin B1-induced neurodegeneration in mice after intracerebroventricular infusion is concurrent with disruption of sphingolipid metabolism and activation of proinflammatory signaling

NeuroToxicology

Volumn 26, Issue 2, 2005, Pages 211-221

  Osuchowski, Marcin F ^a   Edwards, Gaylen L ^a   Sharma, Raghubir P ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

Brain; Cytokines; Fumonisin; Intracerebroventricular infusion; Neurotoxicity; Sphingolipids

Indexed keywords

CERAMIDE; CYTOKINE; FLUORESCENT DYE; FUMONISIN B1; GAMMA INTERFERON; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 1; INTERLEUKIN 6; PROTEIN ANTIBODY; SODIUM CHLORIDE; SPHINGANINE; SPHINGOLIPID; SPHINGOMYELIN; SPHINGOSINE; TUMOR NECROSIS FACTOR ALPHA; FUMONISIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN; BRAIN CORTEX; BRAIN REGION; BRAIN VENTRICLE; CANNULATION; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISSECTION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; LIPID METABOLISM; MOUSE; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; OSMOTIC PUMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; STAINING; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DEGENERATIVE DISEASE; DRUG EFFECT; INFLAMMATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN; FEMALE; FUMONISINS; INFLAMMATION; INJECTIONS, INTRAVENTRICULAR; MICE; MICE, INBRED BALB C; NEURODEGENERATIVE DISEASES; SIGNAL TRANSDUCTION; SPHINGOLIPIDS;

EID: 13844265750     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2004.10.001     Document Type: Article

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