Microwave-assisted synthesis of 1-aryl-3-acetyl-1,4,5,6- tetrahydrobenzimidazo[1,2-d][1,2,4]triazine: First example of a novel ring system

Tetrahedron Letters

Volumn 46, Issue 10, 2005, Pages 1725-1726

  Abdel Jalil, Raid J ^a,b   Voelter, Wolfgang ^b   Stoll, Raphael ^c  

^a HASHEMITE UNIVERSITY   (Jordan)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Benzimidazoles; Microwave assisted synthesis; Triazines

Indexed keywords

BENZIMIDAZOLE DERIVATIVE;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; MICROWAVE IRRADIATION; RING CLOSING METATHESIS; STRUCTURE ANALYSIS;

EID: 13744258873     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.01.050     Document Type: Article

References (14)

1. M. Larhed, C. Moberg, and A. Hallberg Acc. Chem. Res. 35 2002 717 727
2. S. Caddick Tetrahedron 51 1995 10403 104032
3. C. Gabriel, S. Gabriel, H. Grant, B.S.J. Halsstead, and D.M.P. Mingos Chem. Soc. Rev. 27 1998 213 224
4. C.R. Strauss, and R.W. Trainor Aust. J. Chem. 48 1995 1665 1692
5. N.-F.K. Kaiser, U. Bremberg, M. Larhed, C. Moberg, and A. Hallberg J. Organomet. Chem. 603 2000 2 5
6. R.S. Varma, and R. Dahiya Tetrahedron 54 1998 6293 6298
7. R. Zou, K.R. Ayres, J.C. Drach, and L.B.J. Townsend Med. Chem. 39 1996 3477 3482
8. L. Labanauskas, A. Brukstus, E. Undrenaite, P. Gaidelis, V. Bucinskaite, and V. Dauksas Pharmazie 2000 429 431
9. A. Brukstus, D. Melamedaite, and S. Tumkevicius Synth. Commun. 30 2000 3719 3730
10. M. Saeed, R.J. Abdel-Jalil, W. Voelter, and M.M. El-Abadelah Chem. Lett. 2001 660 661
11. Y. Njoya, N. Boufatah, A. Gellis, P. Rathelot, M.P. Crozet, and P. Vanelle Heterocycles 57 2002 1423 1432
12. M.M. El-Abadelah, A.Q. Hussein, and B.A. Thaher Heterocycles 32 1991 1879 1888
13. E. Breitmaier, and W. Voelter Carbon-13 NMR Spectroscopy. High-Resolution Methods and Applications in Organic Chemistry and Biochemistry 1987 VCH Verlagsgesellschaft Weinheim, Fed. Rep. Germany
14. 3) δ: 25.9 (C-11), 44.8 (C-6), 151.2 (CN), 115.2, 115.9, 119.8, 124.1, 124.2, 124.3, 129.6, 144.7, 144. 8, 144.9 (phenyl, C-7, C-8, C-9, C-10), 189.9 (CO)