Chloramphenicol and expression of multidrug efflux pump in Enterobacter aerogenes

Biochemical and Biophysical Research Communications

Volumn 328, Issue 4, 2005, Pages 1113-1118

  Ghisalberti, Didier ^a   Masi, Muriel ^a   Pagès, Jean Marie ^a   Chevalier, Jacqueline ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Chloramphenicol; Efflux pump; Efflux pump inhibitor; Enterobacter aerogenes; Multidrug resistance

Indexed keywords

ACRA PROTEIN; ACRR PROTEIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; BACTERIAL PROTEIN; BETA LACTAM ANTIBIOTIC; CEFEPIME; CEFTAZIDIME; CHLORAMPHENICOL; FLORFENICOL; GENTAMICIN; IMIPENEM; MAR PROTEIN; NALIDIXIC ACID; NORFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TETRACYCLINE; TOLC PROTEIN; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; ENTEROBACTER AEROGENES; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

EID: 13744256306     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.01.069     Document Type: Article

References (31)

1. C. Arpin, C. Coze, A.M. Rogues, J.P. Gachie, C. Bebear, and C. Quentin Epidemiological study of an outbreak due to multidrug-resistant Enterobacter aerogenes in a medical intensive care unit J. Clin. Microbiol. 34 1996 2163 2169
2. C. Bornet, A. Davin-Regli, C. Bosi, J.-M. Pagès, and C. Bollet Imipenem resistance of Enterobacter aerogenes mediated by outer membrane permeability J. Clin. Microbiol. 38 2000 1048 1052
3. R. Canton, A. Oliver, T.M. Coque, M. del Carmen Varela, J.C. Perez-Diaz, and F. Baquero Epidemiology of extended-spectrum β-lactamase-producing Enterobacter isolates in a spanish hospital during a 12-year period J. Clin. Microbiol. 40 2002 1237 1243
4. Y. De Gheldre, M.J. Struelens, Y. Glupczynski, P. De Mol, N. Maes, C. Nonhoff, H. Chetoui, C. Sion, O. Ronveaux, and M. Vaneechoutte National epidemiologic surveys of Enterobacter aerogenes in belgian hospitals J. Clin. Microbiol. 39 2001 889 896
5. C. Bosi, A. Davin-Regli, C. Bornet, M. Malléa, J.-M. Pagès, and C. Bollet Most Enterobacter aerogenes strains in France belong to a prevalent clone J. Clin. Microbiol. 37 1999 2165 2169
6. R.N. Charrel, J.-M. Pagès, P. DeMicco, and M. Malléa Prevalence of outer membrane porin alteration in β-lactam-antibiotic- resistant Enterobacter aerogenes Antimicrob. Agents Chemother. 40 1996 2854 2858
7. J.M. Hopkins, and K.J. Towner Enhanced resistance to cefotaxime and imipenem associated with outer membrane protein alterations in Enterobacter aerogenes J. Antimicrob. Chemother. 25 1990 49 55
8. H. Leying, W. Cullmann, and W. Dick Carbapenem resistance in Enterobacter aerogenes is due to lipopolysaccharide alterations Chemotherapy 37 1991 106 113
9. C. Bornet, R. Chollet, M. Malléa, J. Chevalier, A. Davin-Regli, J.-M. Pagès, and C. Bollet Imipenem and expression of multidrug efflux pump in Enterobacter aerogenes Biochem. Biophys. Res. Commun. 301 2003 985 990
10. S.P. Cohen, L.M. McMurry, D.C. Hooper, J.S. Wolfson, and S.B. Levy Cross-resistance to fluoroquinolones in multiple-antibiotic-resistant (Mar) Escherichia coli selected by tetracycline or chloramphenicol: Decreased drug accumulation associated with membrane changes in addition to OmpF reduction Antimicrob. Agents Chemother. 33 1989 1318 1325
11. L.M. McMurry, A.M. George, and S.B. Levy Active efflux of chloramphenicol in susceptible Escherichia coli strains and in multiple-antibiotic-resistant (Mar) mutants Antimicrob. Agents Chemother. 38 1994 542 546
12. E. Pradel, and J.-M. Pagès The AcrAB-TolC efflux pump contributes to multidrug resistance in the nosocomial pathogen E. aerogenes Antimicrob. Agents Chemother. 46 2002 2640 2643
13. R. Chollet, C. Bollet, J. Chevalier, M. Malléa, J.-M. Pagès, and A. Davin-Regli mar operon involved in multidrug resistance of Enterobacter aerogenes Antimicrob. Agents Chemother. 46 2002 1093 1097
14. M. Malléa, J. Chevalier, C. Bornet, A. Eyraud, A. Davin-Regli, C. Bollet, and J.-M. Pagès Porin alteration and active efflux: Two in vivo drug resistance strategies used by Enterobacter aerogenes Microbiology 144 1998 3003 3009
15. O. Lomovskaya, M.S. Warren, A. Lee, J. Galazzo, R. Fronko, M. Lee, J. Blais, D. Cho, S. Chamberland, T. Renau, R. Leger, S. Hecker, W. Watkins, K. Hoshino, H. Ishida, and V.J. Lee Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: Novel agents for combination therapy Antimicrob. Agents Chemother. 45 2001 105 116
16. M. Malléa, J. Chevalier, A. Eyraud, and J.-M. Pagès Inhibitors of antibiotic efflux pump in resistant Enterobacter aerogenes strains Biochem. Biophys. Res. Commun. 293 2002 1370 1373
17. J. Miller Experiments in molecular genetics 1972 Cold Spring Harbor Laboratory Cold Spring Harbor, NY
18. C.W. Walker, and D.J.F. Brown The reliability of methods for detecting chloramphenicol resistance in Haemophilus influenzae J. Antimicrob. Chemother. 22 1988 905 910
19. S. Gayet, R. Chollet, G. Molle, J.-M. Pagès, and J. Chevalier Modification of outer membrane protein profile and evidence suggesting an active drug pump in Enterobacter aerogenes clinical strains Antimicrob. Agents Chemother. 47 2003 1555 1559
20. S. Schwarz, C. Kehrenberg, B. Doublet, and A. Cloeckaert Molecular basis of bacterial resistance to chloramphenicol and florfenicol FEMS Microbiol. Rev. 28 2004 519 542
21. M.N. Alekshun, and S.B. Levy Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon Antimicrob. Agents Chemother. 41 1997 2067 2075
22. K. Maneewannakul, and S.B. Levy Identification for mar mutants among quinolone-resistant clinical isolates of Escherichia coli Antimicrob. Agents Chemother. 40 1996 1695 1698
23. M.A. Webber, and L.J. Piddock Absence of mutations in marRAB or soxRS in acrB-overexpressing fluoroquinolone-resistant clinical and veterinary isolates of Escherichia coli Antimicrob. Agents Chemother. 45 2001 1550 1552
24. S. Grkovic, M.H. Brown, and R.A. Skurray Regulation of bacterial drug export systems Microbiol. Mol. Biol. Rev. 66 2002 671 701
25. X.Z. Li, and H. Nikaido Efflux-mediated drug resistance in bacteria Drugs 64 2004 159 204
26. U.O. Hasdemir, J. Chevalier, P. Nordmann, and J.-M. Pagès Detection and prevalence of active drug efflux mechanism in various multidrug resistant Klebsiella pneumoniae strains from Turkey J. Clin. Microbiol. 42 2004 2701 2706
27. L. Martinéz-Martinéz, A. Pascual, M.C. Conejo, I. García, P. Joyanes, A. Doménech-Sánchez, and V.J. Benedí Energy-dependent accumulation of norfloxacin and porin expression in clinical isolates of Klebsiella pneumoniae and relationship to extended-spectrum-lactamase production Antimicrob. Agents Chemother. 46 2002 3926 3932
28. A.M. Prouty, I.E. Brodsky, S. Falkow, and J.S. Gunn Bile-salt-mediated induction of antimicrobial and bile resistance in Salmonella typhimurium Microbiology 150 2004 775 783
29. A.M. George Multidrug resistance in enteric and other Gram-negative bacteria FEMS Microbiol. Lett. 139 1996 1 10
30. M.L. Oethinger, I. Podglajen, W. Kern, and S.B. Levy Overexpression of the marA or soxS regulatory gene in clinical topoisomerase mutants of Escherichia coli Antimicrob. Agents Chemother. 42 1998 2089 2094
31. R. Chollet, J. Chevalier, C. Bollet, J.-M. Pagès, and A. Davin-Regli RamA is an alternate activator of the multidrug resistance cascade in Enterobacter aerogenes Antimicrob. Agents Chemother. 48 2004 2518 2523