Investigation into the interaction of the bacterial protease OmpT with outer membrane lipids and biological activity of OmpT:lipopolysaccharide complexes

European Biophysics Journal

Volumn 34, Issue 1, 2005, Pages 28-41

  Brandenburg, Klaus ^a   Garidel, Patrick ^b   Schromm, Andra B ^a   Andrä, Jörg ^a   Kramer, Arjen ^c   Egmond, Maarten ^c   Wiese, Andre ^a  

^a RESEARCH CENTER BORSTEL   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Cytokine induction; LPS; Membrane fluidity; OmpT; Outer membrane

Indexed keywords

BACTERIAL PROTEIN; CARBENE; CYTOKINE; ESTER; LIPID; LIPOPOLYSACCHARIDE; OUTER MEMBRANE PROTEASE T; OUTER MEMBRANE PROTEIN; PHOSPHATE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLGLYCEROL; PHOSPHOLIPID; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CONTAMINATION; CYTOKINE RELEASE; ENZYME RELEASE; FLUIDIZATION; GRAM NEGATIVE BACTERIUM; LIMULUS LYSATE TEST; MELTING POINT; MEMBRANE MODEL; MOLECULAR INTERACTION; MONONUCLEAR CELL; NONHUMAN; OUTER MEMBRANE; PROTEIN FUNCTION; PROTEIN INTERACTION;

ANIMALS; CELL LINE; CELL MEMBRANE; CHO CELLS; CRICETINAE; CRICETULUS; CYTOKINES; HUMANS; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MEMBRANE FLUIDITY; MEMBRANE GLYCOPROTEINS; MEMBRANE LIPIDS; PROTEIN BINDING; RECEPTORS, CELL SURFACE; SERINE ENDOPEPTIDASES; TOLL-LIKE RECEPTORS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; LIMULUS; LIMULUS AMOEBOCYTE; NEGIBACTERIA;

EID: 13744249689     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00249-004-0422-3     Document Type: Article

References (48)

1. Alurkar V, Kamat R (1997) Immunomodulatory properties of porins of some members of the family Enterobacteriaceae. Infect Immun 65:2382-2388
2. Arrondo IL, Goni FM (1999) Structure and dynamics of membrane proteins as studied by infrared spectroscopy. Prog Biophys Mol Biol 72:367-405
3. Beutler B (2000) Endotoxin, Toll-like receptor 4, and the afferent limb of innate immunity. Curr Opin Microbiol 3:23-28
4. Bieback K, Lien E, Klagge IM, Avota E, Schneider-Schaulies J, Duprex WP, Wagner H, Kirschning CI, ter Meulen V, Schneider-Schaulies S (2002) Hemagglutinin protein of wild-type measles virus activates Toll-like receptor 2 signaling. J Virol 76:8729-8736
5. Blume A, Garidel P (1999) Lipid model membranes and biomembranes. In: Gallagher PK, Kemp RB (eds) The handbook of thermal analysis and calorimetry. Elsevier, Amsterdam, pp 109-173
6. Brandenburg K (1993) Fourier transform infrared spectroscopy characterization of the lamellar and nonlamellar structures of free lipid A and Re lipopolysaccharides from Salmonella minnesota and Escherichia coli. Biophys J 64:1215-1231
7. Brandenburg K, Blume A (1987) Investigations into the thermotropic phase behaviour of natural membranes extracted from Gram-negative bacteria and artificial membrane systems made from lipopolysaccharides and free lipid A. Thermochim Acta 119:127-142
8. Brandenburg K, Koch MHJ, Seydel U (1998) Biophysical characterisation of lysozyme binding to LPS Re and lipid A. Eur J Biochem 258:686-695
9. Brandenburg K, Jürgens G, Müller M, Fukuoka S, Koch MHJ (2001) Biophysical characterization of lipopolysaccharide and lipid A inactivation by lactoferrin. Biol Chem 382:1215-1225
10. Brandenburg K, Jürgens G, Andrä J, Lindner B, Koch MHJ, Blume A, Garidel P (2002) Biophysical characterization of the interaction of high-density lipoprotein (HDL) with endotoxins. Eur J Biochem 269:5972-5981
11. Brandenburg K, Moriyon I, Arraiza MD, Lehwark-Yvetot G, Koch MHJ, Seydel U (2002) Biophysical investigations into the interaction of lipopolysaccharide with polymyxins. Thermochim Acta 382:189-198
12. Buschner S. (1999) Bestimmung der kritischen Aggregatkonzentration von Lipiden: Implikationen für die biologische Wirksamkeit von Endotoxinen. PhD Thesis, Universität Kiel
13. Dekker N, Cox RC, Kramer RA, Egmond MR (2001) Substrate specificity of the integral membrane protease OmpT determined by spatially addressed peptide libraries. Biochemistry 40:1694-1701
14. Delude RL, Yoshimura A, Ingalls RR, Golenbock DT (1998) Construction of a lipopolysaccharide receptor cell line and its use in identifying mutants defective in endotoxin but not TNFα, signal transduction. J Immunol 161:3001-3009
15. Friberger P, Sörskog L, Nilsson K, Knös M (1987) The use of a quantitative assay in endotoxin testing. In: Watson SW, Levin J, Novitzky TJ (eds) Detection of bacterial endotoxin with the limulus amebocyte lysate test. Alan Liss, New York, pp 149-169
16. Fringeli UP, Günthard HH (1981) Infrared membrane spectroscopy. In: Grell E (ed) Membrane spectroscopy. Springer, Berlin New York, pp 270-332
17. Galanos C, Lüderitz O, Westphal O (1969) A new method for the extraction of R lipopolysaccharides. Eur J Biochem 9:245-249
18. Galdiero F, Cipollardo de L'Ero G, Benedetto N, Galdiero M, Tufano MA (1993) Release of cytokines induced by Salmonella lyphimurium porins. Infect Immun 61:155-161
19. Galdiero M, D'Isanto M, Vitiello M, Finamore E, Peluso L (2001) Porins from Salmonella enterica serovar Typhimurium induce TNF-alpha, IL-6 and IL-8 release by CD14-independent and CD11a/CD18-dependent mechanisms. Microbiology 147:2697-2704
20. Galdiero M, Vitiello M, Sanzari E, D'Isanto M, Tortora A, Longanella A, Galdiero S (2002) Porins from Salmonella enterica Serovar Typhimurium activate the transcription factors activating protein 1 and NF-kappaB through the Raf-1 mitogen activated protein kinase cascade. Infect Immun 70:558-568
21. Gallati H (1982) Interferon: Wesentlich vereinfachte, enzym-immunologische Bestimmung mit zwei monoklonalen Antikörpern. J Clin Chem Clin Biochem 20:907-914
22. Garidel P, Blume A, Hübner W (2000) A Fourier transform infrared spectroscopic study of the interaction of alkaline earth cations with the negatively charged phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphoglycerol. Biochim Biophys Acta 1466:245-259
23. Gutsmann T, Schromm AB, Koch MHJ, Kusumoto S, Fukase K, Oikawa M, Seydel U, Brandenburg K (2000) Lipopolysaccharide-binding protein-mediated interaction of lipid A from different origin with phospholipid membranes. Phys Chem Chem Phys 2:4521-4528
24. Heine H, Kirschning CJ, Lien E, Monks BG, Rothe M, Golenbock DT (1999) Cutting edge: cells that carry a null allele for Toll-like receptor 2 are capable of responding to endotoxin. J Immunol 162:6971-6975
25. Jürgens G, Müller M, Koch MH J, Brandenburg K (2001) Interaction of hemoglobin with enterobacterial lipopolysaccharide and lipid A. Physicochemical characterization and biological activity. Eur J Biochem 268:4233-4242
26. Jürgens G, Müller M, Garidel P, Koch MHJ, Nakakubo H, Blume A, Brandenburg K (2002) Investigation into the interaction of recombinant human serum albumin with Re-lipopolysaccharide and lipid A. J Endotoxin Res 8:115-126
27. Kauppinen JK, Moffat DJ, Mantsch HH, Cameron DG (1981) Fourier self-deconvolution: a method for resolving intrinsically overlapped bands. Appl Spectrosc 35:271-276
28. Kramer RA, Zandwijken D, Egmond MR, Dekker N (2000) In vitro folding, purification and characterization of Escherichia coli outer membrane protease OmpT. Eur J Biochem 267:885-893
29. Kramer RA, Vandeputte-Rutten L, de Roon GJ, Gros P, Dekker N, Egmond MR (2001) Identification of essential acidic residues of outer membrane protease OmpT supports a novel active site. FEBS Lett 505:426-430
30. Kramer RA, Brandenburg K, Vandeputte-Rutten L, Werkhoven M, Gros P, Dekker N, Egmond MR (2002) Lipopolysaccharide regions involved in the activation of Escherichia coli outer membrane protease OmpT. Eur J Biochem 269:1746-1752
31. Kröner EE, Peskar BA, Fischer H, Ferber E (1981) Control of arachidonic acid accumulation in bone marrow-derived macrophages by acyltransferases. J Biol Chem 256:3690-3697
32. Labischinski H, Barnickel G, Bradaczek H, Naumann D, Rietschel ET, Giesbrecht P (1985) High state of order of isolated bacterial lipopolysaccharide and its possible contribution to the permeation barrier of the outer membrane. J Bacteriol 162:9-20
33. Lindner B, Seydel U (1984) Laser Mikrosonden Massenanalyse (LAMMA) in der Mikrobiologie. Forum Mikrobiol 7:332-338
34. Massari P, Henneke P, Ho Y, Latz E, Golenbock DT, Wetzler LM (2002) Cutting edge: immune stimulation by neisserial porins is Toll-like receptor 2 and MyD88 dependent. J Immunol 168:1533-1537
35. Morr M, Takeuchi O, Akira S, Simon MM, Mühlradt PF (2002) Differential recognition of structural details of bacterial lipopeptides by Toll-like receptors. Eur J Immunol 32:3337-3347
36. Nikaido H (1993) Transport across the bacterial outer membrane. J Bioenerg Biomembr 25:581-589
37. Nikaido H, Vaara,M (1985) Molecular basis of bacterial outer membrane permeability. Microbial Rev 49:1-32
38. Schromm AB, Brandenburg K, Rietschel ET, Flad H-D, Carroll SF, Seydel U (1996) Lipopolysaccharide binding protein (LBP) mediates CD14-independent intercalation of lipopolysaccharide into phospholipid membranes. FEBS Lett 399:267-271
39. Seydel U, Ulmer AJ, Uhlig S, Rietschel ET (1999) Lipopolysaccharide, a membrane-forming and inflammation-inducing bacterial macromolecule. In: Zimmer G (ed) Membrane structure in disease and drug therapy. Marcel Dekker, New York, pp 217-254
40. Seydel U, Oikawa M, Fukase K, Kusumoto S, Brandenburg K (2000) Intrinsic conformation of lipid A is responsible for agonistic and antagonistic activity. Eur J Biochem 267:3032-3039
41. Snyder DS, McIntosh TJ (2000) The lipopolysaccharide barrier: correlation of antibiotic susceptibility with antibiotic permeability and fluorescent probe binding kinetics. Biochemistry 39:11777-11787
42. Stumpe S, Schmid R, Stephens DL, Georgiou G, Bakker EP (1998) Identification of OmpT as the protease that hydrolyses the antimicrobial peptide protamine before it enters growing cells of Escherichia coli. J Bacteriol 180:4002-4006
43. Sugimura K, Nishihara T (1988) Purification, characterization, and primary structure of Escherichia coli protease VII with specificity for paired basic residues: identity of protease V11 and OmpT. J Bacteriol 170:5625-5632
44. Urbanova M, Dukor RK, Pancoska P, Gupta VP, Keiderling TA (1991) Comparison of α-lactalbumin and lysozyme using vibrational circular dichroism. Evidence for a difference in crystal and solution structures. Biochemistry 30:10479-10485
45. Vandeputte-Rutten L, Kramer RA, Kroon J, Dekker N, Egmond MR, Gros P (2001) Crystal structure of the outer membrane protease OmpT from Escherichia coli suggests a novel catalytic site. EMBO J 20:5033-5039
46. Webb RM, Lundrigan MD (1996) OmpT in Escherichia coli correlates with severity of disease in urinary tract infection. Med Microbiol Lett 5:8-14
47. Wiese A, Schröder G, Brandenburg K, Hirsch A, Weite W, Seydel U (1994) Influence of the lipid matrix on incorporation and function of LPS-free porin from Paracoccus denitrificans. Biochim Biophys Acta 1190:231-242
48. Yoshimura A, Lien E, Ingalls RR, Tuomanen E, Dziarski R, Golenbock D (1999) Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. J Immunol 163:1-5