-
1
-
-
13544249718
-
-
Glycopeptide phosphonate derive. EP 1292612, US 2002022590, US 6635618, WO 0198328
-
Leadbetter, M.R., Linsell, M.S. (Theravance, Inc.). Glycopeptide phosphonate derive. EP 1292612, US 2002022590, US 6635618, WO 0198328.
-
-
-
Leadbetter, M.R.1
Linsell, M.S.2
-
2
-
-
2342604041
-
Difunctionalized vancomycin derivative
-
(Sept 27-30, San Diego) Abst F-367
-
Leadbetter, M.R., Linsell, M., Fatheree, P., Trapp, S., Lam, B., Nodwell, M., Shaw, J., Pace, J., Judice, K. Difunctionalized vancomycin derivative. 42nd Intersci Conf Antimicrob Agents Chemother (Sept 27-30, San Diego) 2002, Abst F-367.
-
(2002)
42nd Intersci Conf Antimicrob Agents Chemother
-
-
Leadbetter, M.R.1
Linsell, M.2
Fatheree, P.3
Trapp, S.4
Lam, B.5
Nodwell, M.6
Shaw, J.7
Pace, J.8
Judice, K.9
-
3
-
-
13544254390
-
-
Process for purifying glycopeptide phosphonate derive. US 2003119722, WO 0318608
-
Schmidt, D. Jr., Sganga, J.D. (Theravance, Inc.). Process for purifying glycopeptide phosphonate derive. US 2003119722, WO 0318608.
-
-
-
Schmidt Jr., D.1
Sganga, J.2
-
4
-
-
3042658714
-
Hydrophobic vancomycin derivatives with improved ADME properties: Discovery of telavancin (TD-6424)
-
Leadbetter, M.R., Adams, S.M., Bazzini, B. et al. Hydrophobic vancomycin derivatives with improved ADME properties: Discovery of telavancin (TD-6424). J Antibiot 2004, 57: 326-36.
-
(2004)
J Antibiot
, vol.57
, pp. 326-336
-
-
Leadbetter, M.R.1
Adams, S.M.2
Bazzini, B.3
-
5
-
-
13544266300
-
-
Process for preparing glycopeptide phosphonate derive. US 2003069391, WO 0329270
-
Leadbetter, M., Linsell, M., Lee, J., Liu, J. (Theravance, Inc.). Process for preparing glycopeptide phosphonate derive. US 2003069391, WO 0329270.
-
-
-
Leadbetter, M.1
Linsell, M.2
Lee, J.3
Liu, J.4
-
6
-
-
0026760182
-
The crisis in antibiotic resistance
-
Neu, H.C. The crisis in antibiotic resistance. Science 1992, 257: 1064-73.
-
(1992)
Science
, vol.257
, pp. 1064-1073
-
-
Neu, H.C.1
-
7
-
-
0033580208
-
Emergence of vancomycin resistance in Staphylococcus aureus
-
Smith, T.L., Pearson, M.L., Wilcox, K.R. et al. Emergence of vancomycin resistance in Staphylococcus aureus. New Engl J Med 1999, 340: 493-501.
-
(1999)
New Engl J Med
, vol.340
, pp. 493-501
-
-
Smith, T.L.1
Pearson, M.L.2
Wilcox, K.R.3
-
8
-
-
0037024849
-
Staphylococcus aureus resistant to vancomycin - United States, 2002
-
Sievert, D.M., Boulton, M.L., Stoltman, G. et al. Staphylococcus aureus resistant to vancomycin - United States, 2002. MMWR 2002, 51: 565-7.
-
(2002)
MMWR
, vol.51
, pp. 565-567
-
-
Sievert, D.M.1
Boulton, M.L.2
Stoltman, G.3
-
9
-
-
0037417230
-
Infection with vancomycin-resistant Staphylococcus aureus containing the vanA resistance gene
-
Chang, S., Sievert, D.M., Hageman, J.C. et al. Infection with vancomycin-resistant Staphylococcus aureus containing the vanA resistance gene. New Engl J Med 2003, 348: 1342-7.
-
(2003)
New Engl J Med
, vol.348
, pp. 1342-1347
-
-
Chang, S.1
Sievert, D.M.2
Hageman, J.C.3
-
10
-
-
0032851549
-
Safety and tolerability of quinupristin/dalfopristin: Administration guidelines
-
Rubenstein, E., Prokocimer, P., Talbot, G.H. Safety and tolerability of quinupristin/dalfopristin: Administration guidelines. J Antimicrob Chemother 1999, 44(Suppl. A): 37-46.
-
(1999)
J Antimicrob Chemother
, vol.44
, Issue.SUPPL. A
, pp. 37-46
-
-
Rubenstein, E.1
Prokocimer, P.2
Talbot, G.H.3
-
11
-
-
0035857967
-
Infections due to vancomycin-resistant Enterococcus faecium resistant to linezolid
-
Gonzales, R.D., Schreckenberger, P.C., Graham, M.B., Kelkar, S., DenBesten, K., Quinn, J.P. Infections due to vancomycin-resistant Enterococcus faecium resistant to linezolid. Lancet 2001, 357: 1179.
-
(2001)
Lancet
, vol.357
, pp. 1179
-
-
Gonzales, R.D.1
Schreckenberger, P.C.2
Graham, M.B.3
Kelkar, S.4
Denbesten, K.5
Quinn, J.P.6
-
12
-
-
0033833040
-
Quinupristin/dalfopristin and linezolid: Where, when, which and whether to use?
-
Livermore, D.M. Quinupristin/dalfopristin and linezolid: Where, when, which and whether to use? J Antimicrob Chemother 2000, 46: 347-50.
-
(2000)
J Antimicrob Chemother
, vol.46
, pp. 347-350
-
-
Livermore, D.M.1
-
13
-
-
0027177994
-
Structure-activity relationships of vancomycin-type glycopeptide antibiotics
-
Nagarajan, R. Structure-activity relationships of vancomycin-type glycopeptide antibiotics. J Antibiot 1993, 46: 1181-95.
-
(1993)
J Antibiot
, vol.46
, pp. 1181-1195
-
-
Nagarajan, R.1
-
14
-
-
22444452673
-
Chemical modification of glycopeptide antibiotics [VC1]
-
Pavlov, A.Y., Preobrazhenskaya, M.N. Chemical modification of glycopeptide antibiotics [VC1]. Russ J Bioorg Chem 1998, 24: 570-87.
-
(1998)
Russ J Bioorg Chem
, vol.24
, pp. 570-587
-
-
Pavlov, A.Y.1
Preobrazhenskaya, M.N.2
-
15
-
-
0030875625
-
A new type of chemical modification of glycopeptides antibiotics: Aminomethylated derivatives of eremomycin and their antibacterial activity
-
Pavlov, A.Y., Lazhko, E.I., Preobrazhenskaya, M.N. A new type of chemical modification of glycopeptides antibiotics: Aminomethylated derivatives of eremomycin and their antibacterial activity. J Antibiot 1997, 50: 509-13.
-
(1997)
J Antibiot
, vol.50
, pp. 509-513
-
-
Pavlov, A.Y.1
Lazhko, E.I.2
Preobrazhenskaya, M.N.3
-
16
-
-
0242653645
-
Semi-synthetic glycopeptide antibacterials
-
Judice, U.K., Pace, J.L. Semi-synthetic glycopeptide antibacterials. Bioorg Med Chem Lett 2003, 13: 4165-8.
-
(2003)
Bioorg Med Chem Lett
, vol.13
, pp. 4165-4168
-
-
Judice, U.K.1
Pace, J.L.2
-
17
-
-
10744223657
-
In vitro activity of TD-6424 against Staphylococcus aureus
-
Pace, J.L., Krause, K., Johnston, D. et al. In vitro activity of TD-6424 against Staphylococcus aureus. Antimicrob Agents Chemother 2003, 47: 3602-4.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 3602-3604
-
-
Pace, J.L.1
Krause, K.2
Johnston, D.3
-
18
-
-
2442674119
-
Comparative in vitro activity of telavancin (TD-6424), a rapidly bactericidal, concentration dependent anti-infective with multiple mechanisms of action against Gram-positive bacteria
-
King, A., Phillips, I., Kaniga, K. Comparative in vitro activity of telavancin (TD-6424), a rapidly bactericidal, concentration dependent anti-infective with multiple mechanisms of action against Gram-positive bacteria. J Antimicrob Chemother 2004, 53: 797-803.
-
(2004)
J Antimicrob Chemother
, vol.53
, pp. 797-803
-
-
King, A.1
Phillips, I.2
Kaniga, K.3
-
19
-
-
2542485522
-
In vitro activities of the new semi-synthetic glycopeptide telavancin (TD-6424), vancomycin, daptomycin, linezolid, and four comparator agents against anaerobic Gram-positive species and Corynebacterium spp
-
Goldstein, E.J., Citron, D.M., Merriam, C.V., Warren, Y.A., Tyrrell, K.L., Fernandez, H.T. In vitro activities of the new semi-synthetic glycopeptide telavancin (TD-6424), vancomycin, daptomycin, linezolid, and four comparator agents against anaerobic Gram-positive species and Corynebacterium spp. Antimicrob Agents Chemother 2004, 48: 2149-52.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 2149-2152
-
-
Goldstein, E.J.1
Citron, D.M.2
Merriam, C.V.3
Warren, Y.A.4
Tyrrell, K.L.5
Fernandez, H.T.6
-
20
-
-
13544249714
-
In vitro activity of telavancin (TD-6424) against Bacillus anthracis
-
(Oct 30-Nov 2, Washington DC) Abst E-2010
-
Kaniga, K., Blosser, R.S., Karlowsky, J.A., Sahm, D.F. In vitro activity of telavancin (TD-6424) against Bacillus anthracis. 44th Intersci Conf Antimicrob Agents Chemother (Oct 30-Nov 2, Washington DC) 2004, Abst E-2010.
-
(2004)
44th Intersci Conf Antimicrob Agents Chemother
-
-
Kaniga, K.1
Blosser, R.S.2
Karlowsky, J.A.3
Sahm, D.F.4
-
21
-
-
12744282079
-
Telavancin bactericidal activity against Staphylococcus aureus is mediated by multiple mechanisms
-
(Oct 30-Nov 2, Washington DC) AbSt C1-953
-
Higgins, D.L., Chand, R., Debabov, D.V. et al. Telavancin bactericidal activity against Staphylococcus aureus is mediated by multiple mechanisms. 44th Intersci Conf Antimicrob Agents Chemother (Oct 30-Nov 2, Washington DC) 2004, AbSt C1-953.
-
(2004)
44th Intersci Conf Antimicrob Agents Chemother
-
-
Higgins, D.L.1
Chand, R.2
Debabov, D.V.3
-
22
-
-
13544264523
-
The role of membrane permeabilization in the mode of action of telavancin against vancomycin-sens/tive and -resistant enterococci
-
(Oct 30-Nov 2, Washington DC) Abst C1-952
-
Debabov, D.V., Higgins, D.L., Chang, R. et al. The role of membrane permeabilization in the mode of action of telavancin against vancomycin-sens/tive and -resistant enterococci. 44th Intersci Conf Antimicrob Agents Chemother (Oct 30-Nov 2, Washington DC) 2004, Abst C1-952.
-
(2004)
44th Intersci Conf Antimicrob Agents Chemother
-
-
Debabov, D.V.1
Higgins, D.L.2
Chang, R.3
-
23
-
-
13544260599
-
Effect of human serum on time-kill curves, minimum inhibitory and bactericidal concentrations of TD-6424 against staphylococci and enterococci
-
(Sept 14-17, Chicago) Abst C1-1632
-
Kaniga, K., Johnston, D., Wu, T., Debabov, D., Krause, K., Pace, J.L., Higgins, D., Christensen, B., Judice, K. Effect of human serum on time-kill curves, minimum inhibitory and bactericidal concentrations of TD-6424 against staphylococci and enterococci. 43rd Intersci Conf Antimicrob Agents Chemother (Sept 14-17, Chicago) 2003, Abst C1-1632.
-
(2003)
43rd Intersci Conf Antimicrob Agents Chemother
-
-
Kaniga, K.1
Johnston, D.2
Wu, T.3
Debabov, D.4
Krause, K.5
Pace, J.L.6
Higgins, D.7
Christensen, B.8
Judice, K.9
-
24
-
-
30444448441
-
Effect of pH, media and inoculum size on telavancin (TD-6424) in vitro activity
-
Abst P1762
-
Kaniga, K., Krause, K., Johnston, D., Lane, C., White, L., Wu, T., Debabov, D.V., Pace, J.L., Higgins, D.L. Effect of pH, media and inoculum size on telavancin (TD-6424) in vitro activity. Clin Microbiol Infect 2004, 10(Suppl. 3): Abst P1762.
-
(2004)
Clin Microbiol Infect
, vol.10
, Issue.SUPPL. 3
-
-
Kaniga, K.1
Krause, K.2
Johnston, D.3
Lane, C.4
White, L.5
Wu, T.6
Debabov, D.V.7
Pace, J.L.8
Higgins, D.L.9
-
25
-
-
3342877329
-
Pharmacodynamics of telavancin (TD-6424), a novel bactericidal agent, against Gram-positive bacteria
-
Hegde, S.S., Reyes, N., Wiens, T. et al. Pharmacodynamics of telavancin (TD-6424), a novel bactericidal agent, against Gram-positive bacteria. Antimicrob Agents Chemother 2004, 48: 3043-50.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 3043-3050
-
-
Hegde, S.S.1
Reyes, N.2
Wiens, T.3
-
26
-
-
13544260598
-
Efficacy of telavancin (TD-6424), a rapidly bactericidal agent with multiple mechanisms of action, in a murine model of MRSA pneumonia
-
Abst P1029
-
Hegde, S., Reyes, N., Skinner, R., Kaniga, K. Efficacy of telavancin (TD-6424), a rapidly bactericidal agent with multiple mechanisms of action, in a murine model of MRSA pneumonia. Clin Microbiol Infect 2004, 10(Suppl. 3): Abst P1029.
-
(2004)
Clin Microbiol Infect
, vol.10
, Issue.SUPPL. 3
-
-
Hegde, S.1
Reyes, N.2
Skinner, R.3
Kaniga, K.4
-
27
-
-
13544273288
-
Evaluation of TD-6424 in the rabbit model of aortic valve endocarditis (AVE) due to methicillin-resistant Staphylococcus aureus (MRSA) or vancomycin-intermediate Staphylococcus aureus (VISA)
-
(Sept 14-17, Chicago) Abst F-2111
-
Basuino, L., Madrigal, A.G., Chambers, H.F. Evaluation of TD-6424 in the rabbit model of aortic valve endocarditis (AVE) due to methicillin-resistant Staphylococcus aureus (MRSA) or vancomycin-intermediate Staphylococcus aureus (VISA). 43rd Intersci Conf Antimicrob Agents Chemother (Sept 14-17, Chicago) 2003, Abst F-2111.
-
(2003)
43rd Intersci Conf Antimicrob Agents Chemother
-
-
Basuino, L.1
Madrigal, A.G.2
Chambers, H.F.3
-
28
-
-
2442691016
-
Pharmacokinetic disposition and serum bactericidal activity following IV infusion of single and multiple ascending doses of TD-6424 in healthy male subjects
-
Abst P1214
-
Barriere, S., Shaw, J., Seroogy, J., Kaniga, K., Pace, J., Judice, K., Mant, T. Pharmacokinetic disposition and serum bactericidal activity following IV infusion of single and multiple ascending doses of TD-6424 in healthy male subjects. Clin Microbiol Infect 2003, 9(Suppl. 1): Abst P1214.
-
(2003)
Clin Microbiol Infect
, vol.9
, Issue.SUPPL. 1
-
-
Barriere, S.1
Shaw, J.2
Seroogy, J.3
Kaniga, K.4
Pace, J.5
Judice, K.6
Mant, T.7
-
29
-
-
13544272685
-
Pharmacokinetics (PK) & safety of a new antibacterial, TD-6424 (TD), in healthy subjects
-
(Sept 14-17, Chicago) Abst A-20
-
Barriere, S., Shaw, J.P., Seroogy, J., Spencer, E., Kitt, M. Pharmacokinetics (PK) & safety of a new antibacterial, TD-6424 (TD), in healthy subjects. 43rd Intersci Conf Antimicrob Agents Chemother (Sept 14-17, Chicago) 2003, Abst A-20.
-
(2003)
43rd Intersci Conf Antimicrob Agents Chemother
-
-
Barriere, S.1
Shaw, J.P.2
Seroogy, J.3
Spencer, E.4
Kitt, M.5
-
30
-
-
13544259682
-
Single dose pharmacokinetics (PK) of telavancin (TLV) in healthy elderly subjects
-
Abst P1027
-
Duchin, K., Shaw, J., Spencer, E., Seroogy, J., Barriere, S., Wilbraham, D. Single dose pharmacokinetics (PK) of telavancin (TLV) in healthy elderly subjects. Clin Microbiol Infect 2004, 10(Suppl. 3): Abst P1027.
-
(2004)
Clin Microbiol Infect
, vol.10
, Issue.SUPPL. 3
-
-
Duchin, K.1
Shaw, J.2
Spencer, E.3
Seroogy, J.4
Barriere, S.5
Wilbraham, D.6
-
31
-
-
13544259682
-
Single dose pharmacokinetics (PK) of telavancin (TLV) in subjects with renal dysfunction
-
Abst P1028
-
Duchin, K., Shaw, J., Spencer, E., Seroogy, J., Barriere, S., Wilbraham, D. Single dose pharmacokinetics (PK) of telavancin (TLV) in subjects with renal dysfunction. Clin Microbiol Infect 2004, 10(Suppl. 3): Abst P1028.
-
(2004)
Clin Microbiol Infect
, vol.10
, Issue.SUPPL. 3
-
-
Duchin, K.1
Shaw, J.2
Spencer, E.3
Seroogy, J.4
Barriere, S.5
Wilbraham, D.6
-
32
-
-
2942657731
-
Effects of a new antibacterial, telavancin, on cardiac repolarization (QTc interval duration) in healthy subjects
-
Barriere, S., Genter, F., Spencer, E., Kitt, M., Hoelscher, D., Morganroth, J. Effects of a new antibacterial, telavancin, on cardiac repolarization (QTc interval duration) in healthy subjects. J Clin Pharmacol 2004, 44: 689-95.
-
(2004)
J Clin Pharmacol
, vol.44
, pp. 689-695
-
-
Barriere, S.1
Genter, F.2
Spencer, E.3
Kitt, M.4
Hoelscher, D.5
Morganroth, J.6
-
33
-
-
33750537908
-
Telavancin (TLV) vs standard therapy (ST) for treatment of complicated Gram-positive skin and soft tissue infections (cSSTI)
-
(Sept 30-Oct 3, Boston) Abst 517
-
Stryjewski, M., O'Riordan, W., Lau, W., Pien, F., Fowler, V., Vallee, M., Chu, V., Barriere, S., Kitt, M., Corey, G. Telavancin (TLV) vs standard therapy (ST) for treatment of complicated Gram-positive skin and soft tissue infections (cSSTI). 42nd Annu Meet Infect Dis Soc Am (Sept 30-Oct 3, Boston) 2004, Abst 517.
-
(2004)
42nd Annu Meet Infect Dis Soc Am
-
-
Stryjewski, M.1
O'Riordan, W.2
Lau, W.3
Pien, F.4
Fowler, V.5
Vallee, M.6
Chu, V.7
Barriere, S.8
Kitt, M.9
Corey, G.10
-
34
-
-
13544250580
-
Final phase II results confirm the efficacy of telavancin in cSSSI
-
December 13
-
Final phase II results confirm the efficacy of telavancin in cSSSI. DailyDrugNews.com (Daily Essentials) December 13, 2004.
-
(2004)
DailyDrugNews.com (Daily Essentials)
-
-
-
35
-
-
13544260597
-
Comparative in vitro susceptibility and bactericidal activity of TD-6424 against Streptococcus pneumoniae and non-pneumococcal streptococci from the United States and Europe
-
(Sept 14-17, Chicago) Abst C1-1634
-
Krause, K., Johnston, D., Wu, T., Pace, J., Debabov, D., Judice, K., Higgins, D., Christensen, B., Kaniga, K. Comparative in vitro susceptibility and bactericidal activity of TD-6424 against Streptococcus pneumoniae and non-pneumococcal streptococci from the United States and Europe. 43rdIntersci Conf Antimicrob Agents Chemother (Sept 14-17, Chicago) 2003, Abst C1-1634.
-
(2003)
43rdIntersci Conf Antimicrob Agents Chemother
-
-
Krause, K.1
Johnston, D.2
Wu, T.3
Pace, J.4
Debabov, D.5
Judice, K.6
Higgins, D.7
Christensen, B.8
Kaniga, K.9
-
36
-
-
8544246865
-
The effect of the novel glycopeptide, TD-6424, on biofilms of susceptible and resistant staphylococci
-
(Sept 14-17, Chicago) Abst F-2110
-
Gander, S., Kinnaird, A., Baklavadaki, L., Finch, R. The effect of the novel glycopeptide, TD-6424, on biofilms of susceptible and resistant staphylococci. 43rd Intersci Conf Antimicrob Agents Chemother (Sept 14-17, Chicago) 2003, Abst F-2110.
-
(2003)
43rd Intersci Conf Antimicrob Agents Chemother
-
-
Gander, S.1
Kinnaird, A.2
Baklavadaki, L.3
Finch, R.4
-
37
-
-
13544269987
-
In vivo pharmacodynamics of TD-6424, a novel rapidly bactericidal antibiotic against Gram-positive bacteria
-
(Sept 14-17, Chicago) Abst F-2108
-
Hegde, S.S., Reyes, N., Wiens, T., Skinner, R., McCullough, J., Vanasse, N., Judice, K. In vivo pharmacodynamics of TD-6424, a novel rapidly bactericidal antibiotic against Gram-positive bacteria. 43rd Intersci Conf Antimicrob Agents Chemother (Sept 14-17, Chicago) 2003, Abst F-2108.
-
(2003)
43rd Intersci Conf Antimicrob Agents Chemother
-
-
Hegde, S.S.1
Reyes, N.2
Wiens, T.3
Skinner, R.4
McCullough, J.5
Vanasse, N.6
Judice, K.7
-
38
-
-
33644503929
-
TD-6424, a novel rapidly bactericidal concentration-dependent antibiotic, acts through a unique dual mode of action
-
(Sept 14-17, Chicago) Abst C1-1809
-
Debabov, D.V., Pace, J., Nodwell, M. et al. TD-6424, a novel rapidly bactericidal concentration-dependent antibiotic, acts through a unique dual mode of action. 43rd Intersci Conf Antimicrob Agents Chemother (Sept 14-17, Chicago) 2003, Abst C1-1809.
-
(2003)
43rd Intersci Conf Antimicrob Agents Chemother
-
-
Debabov, D.V.1
Pace, J.2
Nodwell, M.3
-
39
-
-
13544269363
-
Low frequency of spontaneous resistance to TD-6424 and delayed resistance selection in vitro among staphylococci and enterococci
-
(Sept 14-17, Chicago) Abst C1-1810
-
Krause, K., Debabov, D., Pace, J., Kaniga, K. Low frequency of spontaneous resistance to TD-6424 and delayed resistance selection in vitro among staphylococci and enterococci. 43rd Intersci Conf Antimicrob Agents Chemother (Sept 14-17, Chicago) 2003, Abst C1-1810.
-
(2003)
43rd Intersci Conf Antimicrob Agents Chemother
-
-
Krause, K.1
Debabov, D.2
Pace, J.3
Kaniga, K.4
-
40
-
-
34250690945
-
Comparative in vitro activity of TD-6424 against clinical isolates of Enterococcus faecalis and Enterococcus faecium
-
(Sept 14-17, Chicago) Abst C1-1633
-
Wu, T., Pace, J., Farrington, L., Debabov, D., Krause, K., Johnston, D., Judice, K., Higgins, D., Christensen, B., Kaniga, K. Comparative in vitro activity of TD-6424 against clinical isolates of Enterococcus faecalis and Enterococcus faecium. 43rd Intersci Conf Antimicrob Agents Chemother (Sept 14-17, Chicago) 2003, Abst C1-1633.
-
(2003)
43rd Intersci Conf Antimicrob Agents Chemother
-
-
Wu, T.1
Pace, J.2
Farrington, L.3
Debabov, D.4
Krause, K.5
Johnston, D.6
Judice, K.7
Higgins, D.8
Christensen, B.9
Kaniga, K.10
-
41
-
-
30444443668
-
In vitro activities of TD-6424, a novel antiinfective with multiple mechanisms of action, vancomycin (V), daptomycin (D), linezolid (L), and four other agents against anaerobic Gram-positive organisms and Corynebacterium spp
-
(Sept 14-17, Chicago) Abst C1-1639
-
Citron, D.M., Goldstein, E.J.C. In vitro activities of TD-6424, a novel antiinfective with multiple mechanisms of action, vancomycin (V), daptomycin (D), linezolid (L), and four other agents against anaerobic Gram-positive organisms and Corynebacterium spp. 43rd Intersci Conf Antimicrob Agents Chemother (Sept 14-17, Chicago) 2003, Abst C1-1639.
-
(2003)
43rd Intersci Conf Antimicrob Agents Chemother
-
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Citron, D.M.1
Goldstein, E.J.C.2
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42
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30444449725
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Pharmacokinetics of TD-6424, a novel rapidly bactericidal concentration-dependent antibiotic, in preclinical species
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(Sept 14-17, Chicago) Abst F-2109
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Shaw, J., Adams, S., Li, D., Seroogy, J., Jaw-Tsai, S. Pharmacokinetics of TD-6424, a novel rapidly bactericidal concentration-dependent antibiotic, in preclinical species. 43rd Intersci Conf Antimicrob Agents Chemother (Sept 14-17, Chicago) 2003, Abst F-2109.
-
(2003)
43rd Intersci Conf Antimicrob Agents Chemother
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Shaw, J.1
Adams, S.2
Li, D.3
Seroogy, J.4
Jaw-Tsai, S.5
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43
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13544257225
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A randomized, double-blind, placebo- and positive-controlled study of the effects of a new antibacterial, TD-6424 on cardiac repolarization (the QTc interval) in healthy subjects
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Abst O144
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Barriere, S., Genter, F., Spencer, E., Kitt, M., Hoelscher, D., Morganroth, J. A randomized, double-blind, placebo- and positive-controlled study of the effects of a new antibacterial, TD-6424 on cardiac repolarization (the QTc interval) in healthy subjects. Clin Microbiol Infect 2003, 9(Suppl. 1): Abst O144.
-
(2003)
Clin Microbiol Infect
, vol.9
, Issue.SUPPL. 1
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-
Barriere, S.1
Genter, F.2
Spencer, E.3
Kitt, M.4
Hoelscher, D.5
Morganroth, J.6
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44
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11244346464
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Comparative in vitro activity of TD-6424, a rapidly bactericidal, concentration-dependent antibiotic with multiple mechanisms of action against Gram-positive bacteria
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Abst P799
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King, A., Phillips, I., Farrington, L., Pace, J., Kaniga, K. Comparative in vitro activity of TD-6424, a rapidly bactericidal, concentration-dependent antibiotic with multiple mechanisms of action against Gram-positive bacteria. Clin Microbiol Infect 2003, 9(Suppl. 1): Abst P799.
-
(2003)
Clin Microbiol Infect
, vol.9
, Issue.SUPPL. 1
-
-
King, A.1
Phillips, I.2
Farrington, L.3
Pace, J.4
Kaniga, K.5
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45
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9144264415
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Vancomycin-resistant Staphylococcus aureus isolate from a patient in Pennsylvania
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Tenover, F.C., Weigel, L.M., Appelbaum, P.C. et al. Vancomycin-resistant Staphylococcus aureus isolate from a patient in Pennsylvania. Antimicrob Agents Chemother 2004, 48: 275-80.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 275-280
-
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Tenover, F.C.1
Weigel, L.M.2
Appelbaum, P.C.3
-
46
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30444434498
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Telavancin (TLV) is highly efficacious against a penicillin-resistant pneumococcal strain in the rabbit meningitis model
-
(Oct 30-Nov 2, Washington DC) Abst B-938
-
Cottagnoud, P., Cottagnoud, M., Acosta, F., Kühn, F., Pfister, M., Platz, L., Stucki, A. Telavancin (TLV) is highly efficacious against a penicillin-resistant pneumococcal strain in the rabbit meningitis model. 44th Intersci Conf Antimicrob Agents Chemother (Oct 30-Nov 2, Washington DC) 2004, Abst B-938.
-
(2004)
44th Intersci Conf Antimicrob Agents Chemother
-
-
Cottagnoud, P.1
Cottagnoud, M.2
Acosta, F.3
Kühn, F.4
Pfister, M.5
Platz, L.6
Stucki, A.7
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47
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30444445147
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Comparison of telavancin versus daptomycin, linezolid and quinupristin/dalfopristin against 49 glycopeptide non-susceptible Staphylococcus species (GISS) including hetero-resistant (hGISS) and vancomycin resistant S.aureus (VRSA)
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(Oct 30-Nov 2, Washington DC) Abst E-2007
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Leuthner, K.D., Cheung, C., Rybak, M.J. Comparison of telavancin versus daptomycin, linezolid and quinupristin/dalfopristin against 49 glycopeptide non-susceptible Staphylococcus species (GISS) including hetero-resistant (hGISS) and vancomycin resistant S.aureus (VRSA). 44th Intersci Conf Antimicrob Agents Chemother (Oct 30-Nov 2, Washington DC) 2004, Abst E-2007.
-
(2004)
44th Intersci Conf Antimicrob Agents Chemother
-
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Leuthner, K.D.1
Cheung, C.2
Rybak, M.J.3
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48
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13544256383
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In vitro bactericidal activity of telavancin (TLV) against S. aureus with relative tolerance to vancomycin (VAN)
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(Oct 30-Nov 2, Washington DC) Abst E-2011
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Eliopoulos, G.M., Wennersten, C.B., Sakoulas, G., Moellering, R.C. Jr. In vitro bactericidal activity of telavancin (TLV) against S. aureus with relative tolerance to vancomycin (VAN). 44th Intersci Conf Antimicrob Agents Chemother (Oct 30-Nov 2, Washington DC) 2004, Abst E-2011.
-
(2004)
44th Intersci Conf Antimicrob Agents Chemother
-
-
Eliopoulos, G.M.1
Wennersten, C.B.2
Sakoulas, G.3
Moellering Jr., R.C.4
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