The quantification of hCLCA2 and colocalisation with integrin β4 in stratified human epithelia

Acta Histochemica

Volumn 106, Issue 6, 2005, Pages 421-425

  Connon, Che J ^a,b   Kawasaki, Satoshi ^a   Yamasaki, Kenta ^a   Quantock, Andrew J ^b   Kinoshita, Shigeru ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Calcium activated chloride channel; Cell adhesion; Epithelium; Human; Immunohistochemistry; Integrin 4; PCR

Indexed keywords

ADHESION; AMINO ACIDS; ANTIBODIES; CALCIUM; CELLS; CHLORINE; GENETIC ENGINEERING; HYDROCHLORIC ACID; IMMUNOLOGY; MOLECULES; TISSUE;

BASAL CELL; COLOCALISATION; EPITHELIAL TISSUE; FLUORESCENCE MICROSCOPY; IMMUNOLABELLING; MULTIFUNCTIONAL PROTEINS; STRATIFIED;

BIOTECHNOLOGY;

BETA4 INTEGRIN; CALCIUM ACTIVATED CHLORIDE CHANNEL 2 PROTEIN; COLLAGEN TYPE 7; PROTEIN; UNCLASSIFIED DRUG;

ANTIBODY LABELING; ARTICLE; BASAL CELL; CELL ADHESION; CONTROLLED STUDY; EPITHELIUM; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; REAL TIME POLYMERASE CHAIN REACTION;

EID: 13544256488     PISSN: 00651281     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.acthis.2004.08.003     Document Type: Article

References (15)

1. M. Abdel-Ghany, H.-C. Cheng, R.C. Elble, H. Lin, J. DiBiasio, and B.U. Pauli The interacting binding domains of the beta 4 integrin and calcium-activated chloride channels (CLCAs) in metastasis J Biol Chem 278 2003 49406 49416
2. M. Abdel-Ghany, H.C. Cheng, R.C. Elble, and B.U. Pauli The breast cancer beta 4 integrin and endothelial human CLCA2 mediate lung metastasis J Biol Chem 276 2001 25438 25446
3. R.E. Burgeson, G.P. Lunstrum, B. Rokosova, C.S. Rimberg, L.M. Rosenbaum, and D.R. Keene The structure and function of type VII collagen Ann NY Acad Sci 580 1990 32 43
4. W.G. Carter, P. Kaur, S.G. Gil, P.J. Gahr, and E.A. Wayner Distinct functions for integrins alpha 3 beta 1 in focal adhesions and alpha 6 beta 4/bullous pemphigoid antigen in a new stable anchoring contact (SAC) of keratinocytes relation to hemidesmosomes J Cell Biol 111 1990 3141 3154
5. C.J. Connon, K. Yamasaki, S. Kawasaki, A.J. Quantock, N. Koizumi, and S. Kinoshita Calcium-activated chloride channel-2 in human epithelia J Histochem Cytochem 52 2004 415 418
6. J. Cuppoletti, and D.H. Malinowska Ca2+-activated Cl-channels focus on "Molecular cloning and transmembrane structure of hCLCA2 from human lung, trachea, and mammary gland" Am J Physiol 276 1999 C1259 C1260
7. M. De Luca, R.N. Tamara, S. Kajiji, S. Bondanza, P. Rossino, R. Cancedda, P.C. Marchisio, and V. Quaranta Polarized integrin mediates human keratinocyte adhesion to basal lamina Proc Natl Acad Sci USA 87 1990 6888 6892
8. C.M. Fuller, H.L. Ji, A. Tousson, R.C. Elble, B.U. Pauli, and D.J. Benos Ca(2+)-activated Cl(-) channels a newly emerging anion transport family Pflugers Arch 443 Suppl. 1 2001 S107 10
9. A.D. Gruber, and B.U. Pauli Tumorigenicity of human breast cancer is associated with loss of the Ca2+-activated chloride channel CLCA2 Cancer Res 59 1999 5488 5491
10. A.D. Gruber, R.C. Elble, H.L. Ji, K.D. Schreur, C.M. Fuller, and B.U. Pauli Genomic cloning, molecular characterization, and functional analysis of human CLCA1, the first human member of the family of Ca2+-activated Cl- channel proteins Genomics 54 1998 200 214
11. A.D. Gruber, K.D. Schreur, L. Ji H-, C.M. Fuller, and B.U. Pauli Molecular cloning and transmembrane s tructure of hCLCA2 from human lung, trachea, and mammary gland Am J Physiol 276 1999 C1261 C1270
12. R. Itoh, S. Kawamoto, Y. Miyamoto, S. Kinoshita, and K. Okubo Isolation and characterization of a Ca(2+)-activated chloride channel from human corneal epithelium Curr Eye Res 21 2000 918 925
13. T.J. Jentsch, V. Stein, F. Weinreich, and A.A. Zdebik Molecular structure and physiological function of chloride channels Physiol Rev 82 2002 503 568
14. P. Rousselle, D.R. Keene, F. Ruggiero, M.F. Champliaud, M. Rest, and R.E. Burgeson Laminin 5 binds the NC-1 domain of type VII collagen J Cell Biol 138 1997 719 728
15. M.A. Stepp, S. Spurr-Michaud, A. Tisdale, J. Elwell, and I.K. Gipson Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes Proc Natl Acad Sci USA 87 1990 8970 8974