Molecular cloning and transmembrane structure of hCLCA2 from human lung, trachea, and mammary gland

American Journal of Physiology - Cell Physiology

Volumn 276, Issue 6 45-6, 1999, Pages

  Gruber, Achim D ^a   Schreur, Kevin D ^b   Ji, Hong Long ^b   Fuller, Catherine M ^b   Pauli, Bendicht U ^a  

^a Animal Health Diagnostic Center   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Calcium activated chloride channel; Cystic fibrosis

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; CALCIUM ION; CHLORIDE CHANNEL; DITHIOTHREITOL; IONOMYCIN; MEMBRANE PROTEIN; MEMBRANE PROTEIN HCLCA2; NIFLUMIC ACID; TAMOXIFEN; UNCLASSIFIED DRUG;

BREAST; CYSTIC FIBROSIS; DNA LIBRARY; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG; MOLECULAR CLONING; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; TRACHEA;

EID: 0032996624     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1999.276.6.c1261     Document Type: Review

References (10)

1. Anderson, M. P., and M. J. Welsh, Calcium and cyclic AMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia. Proc. Natl. Acad. Sci. USA 88: 6003-6007, 1991.
2. - channels from secretory epithelial cells by low internal pH. J. Membr. Biol. 147: 95-104, 1995.
3. Clarke, L. L., B. R. Grubb, S. E. Gabriel, O. Smithies, B. H. Koller, and R. C. Boucher. Defective epithelial chloride transport in a gene-targeted mouse model of cystic fibrosis. Science 257: 1125-1128, 1992.
4. Clarke, L. L., B. R. Grubb, J. R. Yankaskas, C. U. Cotton, A. McKenzie, and R. C. Boucher. Relationship of a non-cystic fibrosis transmembrane conductance regulator-mediated chloride conductance to organ-level disease in Cftr (-/-) mice. Proc. Natl. Acad. Sci. USA 91: 479-483, 1994.
5. Cravchik, A., and A. A. Matus. A novel strategy for the immunological tagging of cDNA constructs. Gene 137: 139-143, 1993.
6. Cunningham, S. A., M. S. Awayda, J. K. Bubien, I. I. Ismailov, M. P. Arrate, B. K. Berdiev, D. J. Benos, and C. M. Fuller. Cloning of an epithelial chloride channel from bovine trachea. J. Biol. Chem. 270: 31016-31026, 1995.
7. Devi, L. Consensus sequence for processing of polypeptide precursors at monobasic sites, FEBS Lett. 280: 189-194, 1991.
8. Elble, R., J. Widom, A. D. Gruber, M. Abdel-Ghany, R. Levine, A. Goodwin, H.-C. Cheng, and B. U. Pauli. Cloning and characterization of lung-endothelial cell adhesion molecule-1 suggest it is an endothelial chloride channel. J. Biol. Chem. 272: 27853-27861, 1997.
9. Gandhi, R., R. C. Elble, A. D. Gruber, H.-L. Ji, S. M. Copeland, C. M. Fuller, and B. U. Pauli. Molecular and functional characterization of a calcium-sensitive chloride channel from mouse lung. J. Biol. Chem. 273: 32096-32101, 1998.
10. - secretion in nasal epithelia of CF mice. Am. J. Physiol. 266 (Cell Physiol. 35): C1479-C1483, 1994.