Expression profiling of human hepatoma cells reveals global repression of genes involved in cell proliferation, growth, and apoptosis upon infection with parvovirus H-1

Journal of Virology

Volumn 79, Issue 4, 2005, Pages 2274-2286

  Li, Jianhong ^a,b   Werner, Ekkehard ^b   Hergenhahn, Manfred ^b   Poirey, Rémy ^b   Luo, Zuyu ^a   Rommelaere, Jean ^b   Jauniaux, Jean Claude ^b  

^a FUDAN UNIVERSITY   (China)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; TRANSCRIPTION FACTOR;

APOPTOSIS; ARTICLE; BACTERIOPHAGE; CELL CULTURE; CELL CYCLE S PHASE; CELL GROWTH; CELL PROLIFERATION; CELL SYNCHRONIZATION; CYTOPATHOGENIC EFFECT; DNA MICROARRAY; DOWN REGULATION; GENE EXPRESSION; GENE REPRESSION; GENE SEQUENCE; GENETIC TRANSCRIPTION; HEPATOMA CELL; HOST CELL; IMMUNE RESPONSE; IMMUNOFLUORESCENCE; NUCLEOTIDE SEQUENCE; ONCOGENE MYC; PARVOVIRUS; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR CELL; VIRUS INFECTION; VIRUS TRANSCRIPTION; WESTERN BLOTTING;

APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; PARVOVIRUS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, VIRAL; TIME FACTORS;

DNA VIRUSES; H 1 VIRUS; PARVOVIRUS; PARVOVIRUS H1;

EID: 13444270802     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.4.2274-2286.2005     Document Type: Article

References (73)

1. Anouja, F., R. Wattiez, S. Mousset, and P. Caillet-Fauquet. 1997. The cytotoxicity of the parvovirus minute virus of mice nonstructural protein NS1 is related to changes in the synthesis and phosphorylation of cell proteins. J. Virol. 71:4671-4678.
2. Bashir, T., R. Hörlein, J. Rommelaere, and K. Willwand. 2000. Cyclin A activates the DNA polymerase δ-dependent elongation machinery in vitro: a parvovirus DNA replication model. Proc. Natl. Acad. Sci. USA 97:5522-5527.
3. Bodendorf, U., C. Cziepluch, J. C. Jauniaux, J. Rommelaere, and N. Salomé. 1999. Nuclear export factor CRM1 interacts with nonstructural proteins NS2 from parvovirus minute virus of mice. J. Virol. 73:7769-7779.
4. Brandenburger, A., D. Legendre, B. Avalosse, and J. Rommelaere. 1990. NS-1 and NS-2 proteins may act synergistically in the cytopathogenicity of parvovirus MVMp. Virology 174:576-584.
5. Brockhaus K., S. Plaza, D. J. Pintel, J. Rommelaere, and N. Salomé. 1996. Nonstructural proteins NS2 of minute virus of mice associate in vivo with 14-3-3 protein family members. J. Virol. 70:7527-7534.
6. Caillet-Fauquet, P., M. Perros, A. Brandenburger, P. Spegelaere, and J. Rommelaere. 1990. Programmed killing of human cells by means of an inducible clone of parvoviral genes encoding non-structural proteins. EMBO J. 9:2989-2995.
7. Chakravarti, D., V. Ogryzko, H. Y. Kao, A. Nash, H. Chen, Y. Nakatani, and R. M. Evans. 1999. A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity. Cell 96:393-403.
8. Christensen, J., S. F. Cotmore, and P. Tattersall. 1997. Parvoviras initiation factor PIF: a novel human DNA-binding factor which coordinately recognizes two ACGT motifs. J. Virol. 71:5733-5741.
9. Cornelis, J. J., N. Salomé, C. Dinsart, and J. Rommelaere. 2004. Vectors based on autonomous parvoviruses: novel tools to treat cancer? J. Gene Med. 6(Suppl. 1):S193-S202.
10. Cotmore, S. F., J. Christensen, J. P. Nuesch, and P. Tattersall. 1995. The NS1 polypeptide of the murine parvoviras minute virus of mice binds to DNA sequences containing the motif [ACCA]2-3. J. Virol. 69:1652-1660.
11. Cotmore, S. F., A. M. D'Abramo, Jr., L. F. Carbonell, J. Bratton, and P. Tattersall. 1997. The NS2 polypeptide of parvovirus MVM is required for capsid assembly in murine cells. Virology 231:267-280.
12. Cotmore, S. F., and P. Tattersall. 1987. The autonomously replicating parvoviruses of vertebrates. Adv. Virus Res. 33:91-174.
13. Cziepluch, C., E. Kordes, R. Poirey, A. Grewenig, J. Rommelaere, and J. C. Jauniaux. 1998. Identification of a novel cellular TPR-containing protein, SGT, that interacts with the nonstructural protein NS1 of parvovirus H-1. J. Virol. 72:4149-4156.
14. Dai, Y., B. Gold, J. K. Vishwanatha, and S. L. Rhode. 1994. Mimosine inhibits viral DNA synthesis through ribonucleotide reductase. Virology 205:210-216.
15. KIP-overexpressing cells versus serum-starved or growing cells. Mol. Cell. Biol. 18:409-419.
16. Eichwald, V., L. Daeffler, M. Klein, J. Rommelaere, and N. Salomé. 2002. The NS2 proteins of parvovirus minute virus of mice are required for efficient nuclear egress of progeny virions in mouse cells. J. Virol. 76:10307-10319.
17. Everett, H., and G. McFadden. 1999. Apoptosis: an innate immune response to virus infection. Trends Microbiol. 7:160-165.
18. Faisst, S. R., S. Faisst, C. Grangette, J. R. Schlehofer, and J. Rommelaere. 1993. NFκB upstream regulatory sequences of the HIV-1 LTR are involved in the inhibition of HIV-1 promoter activity by the NS proteins of autonomous parvoviruses H-1 and MVMp. Virology 197:770-773.
19. Fuks, F., L. Deleu, C. Dinsart, J. Rommelaere, and S. Faisst. 1996. ras oncogene-dependent activation of the P4 promoter of minute virus of mice through a proximal P4 element interacting with the Ets family of transcription factors. J. Virol. 70:1331-1339.
20. Granville, D. J., C. M. Carthy, D. Yang, D. W. Hunt, and B. M. McManus. 1998. Interaction of viral proteins with host cell death machinery. Cell Death Differ. 5:653-659.
21. Guo, L., G. Li, H. Xu, W. Lin, H. Huang, Z. Luo, and Z. Su. 1999. p53 gene expression of human hepatoma cell lines and their sensitivities to parvovirus H-1. Shi Yan Sheng Wu Xue Bao 32:23-29.
22. Hardt, N., C. Dinsart, S. Spadari, G. Pedrali-Noy, and J. Rommelaere. 1983. Interrelation between viral and cellular DNA synthesis in mouse cells infected with the parvovirus minute virus of mice. J. Gen. Virol. 64:1991-1998.
23. Harris, A. L. 2002. Hypoxia-a key regulatory factor in tumour growth. Nat. Rev. Cancer 2:38-47.
24. Jain, M., C. Arvanitis, K. Chu, W. Dewey, E. Leonhardt, M. Trinh, C. D. Sundberg, J. M. Bishop, and D. W. Felsher. 2002. Sustained loss of a neoplastic phenotype by brief inactivation of MYC. Science 297:102-104.
25. Jenkins, H. L., and C. A. Spencer. 2001. RNA polymerase II holoenzyme modifications accompany transcription reprogramming in herpes simplex virus type 1-infected cells. J. Virol. 75:9872-9884.
26. Kestler, J., B. Neeb, S. Struyf, J. Van Damme, S. F. Cotmore, A. D'Abramo, P. Tattersall, J. Rommelaere, C. Dinsart, and J. J. Cornelis. 1999. cis requirements for the efficient production of recombinant DNA vectors based on autonomous parvoviruses. Hum. Gene Ther. 10:1619-1632.
27. Krady, J. K., and D. C. Ward. 1995. Transcriptional activation by the parvoviral nonstructural protein NS-1 is mediated via a direct interaction with Sp1. Mol. Cell. Biol. 15:524-533.
28. Lachmann, S., J. Rommeleare, and J. P. F. Nüesch. 2003. Novel PKCη is required to activate replicative functions of the major nonstructural protein NS1 of minute virus of mice. J. Virol. 77:8048-8060.
29. 1 phase of the mammalian cell cycle. Exp. Cell Res. 186:332-339.
30. Lang, S. 2003. Ph.D. thesis. Universität Heidelberg, Heidelberg, Germany. [Online.] http://www.ub.uni-heidelberg.de/archiv/3380.
31. Legendre, D., and J. Rommelaere. 1992. Terminal regions of the NS-1 protein of the parvovirus minute virus of mice are involved in cytotoxicity and promoter trans inhibition. J. Virol. 66:5705-5713.
32. Legrand, C., J. Rommelaere, and P. Caillet-Fauquet. 1993. MVM(p) NS-2 protein expression is required with NS-1 for maximal cytotoxicity in human transformed cells. Virology 195:149-155.
33. Le May, N., S. Dubaele, L. P. De Santis, A. Billecocq, M. Bouloy, and J. M. Egly. 2004. TFIIH transcription factor, a target for the Rift Valley hemorrhagic fever virus. Cell 116:541-550.
34. Leung, D. W., G. Cachianes, W. J. Kuang, D. V. Goeddel, and N. Ferrara. 1989. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246:1306-1309.
35. Lopez-Guerrero, J. A., B. Rayet, M. Tuynder, J. Rommelaere, and C. Dinsart. 1997. Constitutive activation of U937 promonocytic cell clones selected for their resistance to parvovirus H-1 infection. Blood 89:1642-1653.
36. Lorson, C., J. Pearson, L. Burger, and D. J. Pintel. 1998. An Sp1-binding site and TATA element are sufficient to support full transactivation by proximally bound NS1 protein of minute virus of mice. Virology 240:326-337.
37. Mechta-Grigoriou, F., D. Gerald, and M. Yaniv. 2001. The mammalian Jun proteins: redundancy and specificity. Oncogene 20:2378-2389.
38. Merola, M., B. Blanchard, and M. G. Tovey. 1996. The kappa B enhancer of the human interleukin-6 promoter is necessary and sufficient to confer an IL-1 beta and TNF-alpha response in transfected human cell lines: requirement for members of the C/EBP family for activity. J. Interferon Cytokine Res. 16:783-798.
39. Miao, L., P. Yi, Y. Wang, and M. Wu. 2003. Etoposide upregulates Bax-enhancing tumour necrosis factor-related apoptosis inducing ligand-mediated apoptosis in the human hepatocellular carcinoma cell line QGY-7703. Eur. J. Biochem. 270:2721-2731.
40. Moehler, M., B. Blechacz, N. Weiskopf, M. Zeidler, W. Stremmel, J. Rommelaere, P. R. Galle, and J. J. Cornelis. 2001. Effective infection, apoptotic cell killing and gene transfer of human hepatoma cells but not primary hepatocytes by parvovirus H1 and derived vectors. Cancer Gene Ther. 8:158-167.
41. Moehler, M., M. Zeidler, J. Schede, J. Rommelaere, P. R. Galle, J. J. Cornelis, and M. Heike. 2003. Oncolytic parvovirus H1 induces release of heat-shock protein HSP72 in susceptible human tumor cells but may not affect primary immune cells. Cancer Gene Ther. 10:477-480.
42. Mousset, S., Y. Ouadrhiri, P. Caillet-Fauquet, and J. Rommelaere. 1994. The cytotoxicity of the autonomous parvovirus minute virus of mice non-structural proteins in FR3T3 rat cells depends on oncogene expression. J. Virol. 68:6446-6453.
43. Norton, J. D., and G. T. Atherton. 1998. Coupling of cell growth control and apoptosis functions of Id proteins. Mol. Cell. Biol. 18:2371-2381.
44. Nüesch, J. P., S. F. Cotmore, and P. Tattersall. 1995. Sequence motifs in the replicator protein of parvovirus MVM essential for nicking and covalent attachment to the viral origin: identification of the linking tyrosine. Virology 209:122-135.
45. Nüesch, J. P., S. Lachmann, R. Corbau, and J. Rommelaere. 2003. Regulation of minute virus of mice NS1 replicative functions by atypical PKCλ in vivo. J. Virol. 77:433-442.
46. Oehler, M. K., C. Norbury, S. Hague, M. C. Rees, and R. Bicknell. 2001. Adrenomedullin inhibits hypoxic cell death by upregulation of Bcl-2 in endometrial cancer cells: a possible promotion mechanism for tumour growth. Oncogene 20:2937-2945.
47. Ohshima, T., E. Yoshida, T. Nakajima, K. I. Yagami, and A. Fukamizu. 2001. Effects of interaction between parvovirus minute virus of mice NS1 and coactivator CBP on NS1- and p53-transactivation. Int. J. Mol. Med. 7:49-54.
48. cip1. J. Virol. 75:11071-11078.
49. Pelengaris, S., M. Khan, and G. Evan. 2002. c-MYC: more than just a matter of life and death. Nat. Rev. Cancer 2:764-776.
50. Perros, M., L. Deleu, J.-M. Vanacker, Z. Kherrouche, N. Spruyt, S. Faisst, and J. Rommelaere. 1995. Upstream CREs participate in the basal activity of minute virus of mice promoter P4 and in its stimulation in ras-transformed cells. J. Virol. 69:5506-5515.
51. Pitti, R. M., S. A. Marsters, D. A. Lawrence, M. Roy, F. C. Kischkel, P. Dowd, A. Huang, C. J. Donahue, S. W. Sherwood, D. T. Baldwin, P. J. Godowski, W. I. Wood, A. L. Gurney, K. J. Hillan, R. L. Cohen, A. D. Goddard, D. Botstein, and A. Ashkenazi. 1998. Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer. Nature 396:699-703.
52. Rayet, B., J.-A. Lopez-Guerrero, J. Rommelaere, and C. Dinsart. 1998. Induction of programmed cell death by parvovirus H-1 in U937 cells: connection with the tumor necrosis factor alpha signalling pathway. J. Virol. 72:8893-8903.
53. Rhode, S. L., III. 1973. Replication process of the parvovirus H-1. I. Kinetics in a parasynchronous cell system. J. Virol. 11:856-861.
54. Rhode, S. L., III, and S. M. Richard. 1987. Characterization of the transactivation-responsive element of the parvovirus H-1 P38 promoter. J. Virol. 61:2807-2815.
55. Rommelaere, J., and J. J. Cornelis. 1991. Antineoplastic activity of parvoviruses. J. Virol. Methods 33:233-251.
56. Salomé, N., B. van Hille, N. Duponchel, G. Meneguzzi, F. Cuzin, J. Rommelaere, and J. J. Cornelis. 1990. Sensitization of transformed rat cells to parvovirus MVMp is restricted to specific oncogenes. Oncogene 5:123-130.
57. Schlehofer, J. R., M. Rentrop, and D. N. Mannel. 1992. Parvoviruses are inefficient in inducing interferon-beta, tumor necrosis factor-alpha, or interleukin-6 in mammalian cells. Med. Microbiol. Immunol. 181:153-164.
58. Shi, Z. Y., C. W. Ma, J. Huang, W. M. Lin, R. C. Dong, and Z. Y. Luo. 1997. Inhibition of parvovirus H-1 on transplantable human hepatoma and its histological and histobiochemical studies. Shi Yan Sheng Wu Xue Bao 30:247-259.
59. Shoshani, T., A. Faerman, I. Mett, E. Zelin, T. Tenne, S. Gorodin, Y. Moshel, S. Elbaz, A. Budanov, A. Chajut, H. Kalinski, I. Kamer, A. Rozen, O. Mor, E. Keshet, D. Leshkowitz, P. Einat, R. Skaliter, and E. Feinstein. 2002. Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis. Mol. Cell. Biol. 22:2283-2293.
60. Siegl, G., and M. Gautschi. 1973. The multiplication of parvovirus Lu3 in a synchronized culture system. II. Biochemical characteristics of virus replication. Arch. Gesamte Virusforsch. 40:119-127.
61. Soldani, C., and A. I. Scovassi. 2002. Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update. Apoptosis 7:321-328.
62. Song, L., A. Mercado, N. Vazquez, Q. Xie, R. Desai, A. L. George, Jr., G. Gamba, and D. B. Mount. 2002. Molecular, functional, and genomic characterization of human KCC2, the neuronal K-Cl cotransporter. Brain Res. Mol. Brain Res. 103:91-105.
63. Staller, P., J. Sulitkova, J. Lisztwan, H. Moch, E. J. Oakeley, and W. Krek. 2003. Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL. Nature 425:307-311.
64. Stilwell, J. L., and R. J. Samulski. 2004. Role of viral vectors and virion shells in cellular gene expression. Mol. Ther. 9:337-346.
65. Su, Z. Z., Z. Y. Luo, L. P. Guo, J. Z. Li, and Y. L. Liu. 1988. Inhibitory effect of parvovirus H-1 on cultured human tumour cells or transformed cells. Sci. Sin. Ser. B 31:69-80.
66. Tattersall, P., and J. Bratton. 1983. Reciprocal productive and restrictive virus-cell interactions of immunosuppressive and prototype strains of minute virus of mice. J. Virol. 46:944-955.
67. Vanacker, J.-M., R. Corbau, G. Adelmant, M. Perros, V. Laudet, and J. Rommelaere. 1996. Transactivation of a cellular promoter by the NS1 protein of the parvovirus minute virus of mice through a putative hormone-responsive element. J. Virol. 70:2369-2377.
68. Volpert, O. V., R. Pili, H. A. Sikder, T. Nelius, T. Zaichuk, C. Morris, C. B. Shiflett, M. K. Devlin, K. Conant, and R. M. Alani. 2002. Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1. Cancer Cell. 2:473-483.
69. Wilson, G. M., H. K. Jindal, D. E. Yeung, W. Chen, and C. R. Astell. 1991. Expression of minute virus of mice major nonstractural protein in insect cells: purification and identification of ATPase and helicase activities. Virology 185:90-98.
70. Wrzesinski, C., L. Tesfay, N. Salomé, J. C. Jauniaux, J. Rommelaere, J. Cornelis, and C. Dinsart. 2003. Chimeric and pseudotyped parvoviruses minimize the contamination of recombinant stocks with replication-competent viruses and identify a DNA sequence that restricts parvovirus H-1 in mouse cells. J. Virol. 77:3851-3858.
71. Yan, S., C. Ma, X. Chen, S. Wan, and Z. Luo. 1994. Inhibitory effect of parvovirus H-1 on the formation of colonies of human hepatoma cell line in vitro and its tumours in nude mice. Cell Res. 4:47-56.
72. Young, P. J., K. T. Jensen, L. R. Burger, D. J. Pintel, and C. L. Lorson. 2002. Minute virus of mice NS1 interacts with the SMN protein, and they colocalize in novel nuclear bodies induced by parvovirus infection. J. Virol. 76:3892-3904.
73. Zhang, H., Y. Ramanathan, P. Soteropoulos, M. L. Recce, and P. P. Tolias. 2002. EZ-Retrieve: a web-server for batch retrieval of coordinate-specified human DNA sequences and underscoring putative transcription factor-binding sites. Nucleic Acids Res. 30:E121.