Secretion of prostatic specific antigen, proliferative activity and androgen response in epithelial-stromal co-cultures from human prostate carcinoma

International Journal of Andrology

Volumn 28, Issue 1, 2005, Pages 39-46

  Castellón, Enrique A ^a   Venegas, Karina ^a   Sáenz, Leonardo ^a   Contreras, Héctor ^a   Huidobro, Christian ^b  

^a UNIVERSITY OF CHILE   (Chile)

^b HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE   (Chile)

Author keywords

Paracrine regulation; Primary cell culture; Prostate cancer; PSA secretion

Indexed keywords

ANDROGEN; FORMAZAN; PROSTATE CARCINOMA TUMOR ANTIGEN 1; PROSTATE SPECIFIC ANTIGEN; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL STRUCTURE; COCULTURE; CONTROLLED STUDY; ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MICROPARTICLE ENZYME IMMUNOASSAY; PARACRINE SIGNALING; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; STATISTICAL ANALYSIS; STROMA CELL;

COCULTURE TECHNIQUES; EPITHELIAL CELLS; HUMANS; MALE; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; STROMAL CELLS;

EID: 13444265179     PISSN: 01056263     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2605.2004.00509.x     Document Type: Article

References (33)

1. Bayne, C. W., Donnelly, F., Chapman, K., Bollina, P., Buck, C. & Habib, F. K. (1998a) A novel coculture model for benign prostatic hyperplasia expressing both isoforms of 5 alpha-reductase. Journal of Clinical Endocrinology and Metabolism 83, 206-213.
2. Bayne, C. W., Ross, M., Donnelly, F., Chapman, K., Buck, C., Bollina, P. & Habib, F. K. (1998b) Selective interactions between prostate fibroblast and epithelial cells in co-culture maintain the BPH phenotype. Urologia International 61, 1-7.
3. Carmichael, J., DeGraff, W. G., Gazdar, A. F., Minna, J. D. & Mitchell, J. B. (1987) Evaluation of a tetrazolium-based semi-automated colorimetric assay: assessment of radiosensitivity. Cancer Research 47, 943-946.
4. Cunha, G. R., Hayward, S. W., Wang, Y. Z. & Ricke, W. A. (2003) Role of the stromal microenvironment in carcinogenesis of the prostate. International Journal of Cancer 107, 1-10.
5. Davies, P. & Eaton, C. L. (1991) Regulation of prostate growth. Journal of Endocrinology 131, 5-17.
6. Dondi, D., Limonta, P., Moretti, R., Marelli, M., Garattini, E. & Motta, M. (1994) Antiproliferative effects of luteinizing hormone-releasing hormone (LHRH) agonists on human androgen-independent prostate cancer cell line DU 145: evidence for an autocrine-inhibitory LHRH loop. Cancer Research 54, 4091-4095.
7. Fekete, M., Redding, T., Comaru-Scahlly, A., Pontes, J., Connelly, R., Srkalovic, G. & Schally, A. (1989) Receptors for luteinizing hormone-releasing hormone, somatostatin, prolactin, and epidermal growth factor in rat and human prostate cancers and in benign prostate hyperplasia. Prostate 14, 191-208.
8. Garnick, M. B. (1993) Prostate cancer: screening, diagnosis, and management. Annals of Internal Medicine 118, 804-818.
9. Gittes, R. F. (1991) Carcinoma of the prostate. New England Journal of Medicine 324, 236-245.
10. Gleason, D. F. & Mellinger, G. T. (1974) Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging. Journal of Urology 111, 58-64.
11. Gleave, M., Hsieh, J. T., Gao, C. A., von Eschenbach, A. C. & Chung, L. W. (1991) Acceleration of human prostate cancer growth in vivo by factors produced by prostate and bone fibroblasts. Cancer Research 51, 3753-3761.
12. Gleave, M. E., Hsieh, J. T., von Eschenbach, A. C. & Chung, L. W. (1992) Prostate and bone fibroblasts induce human prostate cancer growth in vivo: implications for bidirectional tumor-stromal cell interaction in prostate carcinoma growth and metastasis. Journal of Urology 147, 1151-1159.
13. Greiff, A. H., Fischer, W. M. & Sehgal, I. (2002) Paracrine communication between malignant and non-malignant prostate epithelial cells in culture alters growth rate, matrix protease secretion and in vitro invasion. Clinical and Experimental Metastasis 19, 727-733.
14. Habib, F. K., Ross, M. & Bayne, C. W. (2000) Development of a new in vitro model for the study of benign prostatic hyperplasia. Prostate (Supplement) 9, 15-20.
15. Hayward, S. W., DelBuono, R., Deshpande, N. & Hall, P. A. (1992) A functional model of adult human prostate epithelium. The role of androgens and stroma in architectural organization and the maintenance of differentiated secretory function. Journal of Cell Science 102, 361-372.
16. Janecki, A. & Steinberger, A. (1987) Bipolar secretion of androgen-binding protein and transferrin by Sertoli cells cultured in a two-compartment culture chamber. Endocrinology 120, 291-298.
17. Jungwirth, A., Schally, A. V., Pinski, J., Halmos, G., Groot, K., Armatis, P. & Vadillo-Buenfil, M. (1997) Inhibition of in vivo proliferation of androgen-independent prostate cancers by an antagonist of growth hormone-releasing hormone. British Journal of Cancer 75, 1585-1592.
18. Kadar, T., Ben-David, M., Pontes, J., Fekete, M. & Schally, A. (1988) Prolactin and luteinizing hormone-releasing hormone receptors in human benign prostatic hyperplasia and prostate cancer. Prostate 12, 299-307.
19. Lamharzi, N., Halmos, G., Armatis, P. & Schally, A. (1998) Expression of mRNA for luteinizing hormone-releasing hormone receptors and epidermal growth factor receptors in human cancer cell lines. International Journal of Oncology 12, 671-675.
20. Lang, S. H., Stower, M. & Maitland, N. J. (2000) In vitro modelling of epithelial and stromal interactions in non-malignant and malignant prostates. British Journal of Cancer 82, 990-997.
21. Limonta, P., Dondi, D., Moretti, R., Maggi, R. & Motta, M. (1992) Antiproliferative effects of luteinizing hormone-releasing hormone agonists on the human prostatic cancer cell line LNCaP. Journal of Clinical Endocrinology and Metabolism 75, 207-212.
22. Lubrano, C., Toscano, V., Petrangeli, E., Spera, G., Trotta, M., Rombola, N., Frati, L., Di Silverio, F. & Sciarra, F. (1993) Relationship between epidermal growth factor and its receptor in human benign prostatic hyperplasia. Journal of Steroid Biochemistry and Molecular Biology 46, 463-468.
23. Moretti, R., Marelli, M., Dondi, D., Poletti, A., Martini, L., Motta, M. & Limonta, P. (1996) Luteinizing hormone-releasing hormone agonists interfere with the stimulatory actions of epidermal growth factor in human prostatic cancer cell lines, LNCaP and DU 145. Journal of Clinical Endocrinology and Metabolism 81, 3930-3937.
24. Peehl, D. M. (1996) Cellular biology of prostatic growth factors. Prostate (Supplement) 6, 74-78.
25. Redding, T., Schally, A., Radulovic, S., Milovanovic, S., Szapeshazi, K. & Isaacs, J. (1992) Sustained release formulations of luteinizing hormone-releasing hormone antagonist SB-75 inhibit proliferation and enhance apoptotic cell death of human prostate carcinoma (PC-82) in male nude mice. Cancer Research 52, 2538-2544.
26. Rui, H. & Purvis, K. (1988) Hormonal control of prostate function. Scandinavian Journal of Urololgy and Nephrology 107, 32-38.
27. Ruijter, E., Van de Kaa, C., Miller, G., Ruiter, D., Debruyne, F. & Schalken, J. (1999) Molecular genetics and epidemiology of prostate carcinoma. Endocrine Reviews 20, 22-45.
28. Sanchez de la Muela, P., Povo Castilla, J., Bobillo de Lamo, M., Rosales, F. & Perez-Piqueras, J. L. (1995) Microparticle immunoenzymatic assay for detection of prostate specific antigen: characterization of the technique and comparative analysis with a monoclonal immunoradiometric assay. Military Medicine 160, 416-419.
29. Scott, L. J., Clarke, N. W., Sharrard, M. S., George, N. J. & Lang, S. H. (2000) Invasive phenotype of primary human prostatic epithelial cells. Prostate Cancer and Prostatic Diseases 3 (S1), S8.
30. Su, Z. Z., Lin, J., Shen, R., Fisher, P. E., Goldstein, N. I. & Fisher, P. B. (1996) Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family. Proceeding of the National Academy of Science USA 93, 7252-7257.
31. Sung, S. Y. & Chung, L. W. (2002) Prostate tumor-stroma interaction: molecular mechanisms and opportunities for therapeutic targeting. Differentiation 70, 506-521.
32. Wilding, G. (1992) The importance of steroid hormones in prostate cancer. Cancer Surveys 14, 113-130.
33. Wong, Y. C. & Wang, Y. Z. (2000) Growth factors and epithelial-stromal interactions in prostate cancer development. International Review of Cytology 199, 65-116.